Rebecca Lee Linn, M.D.

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Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
The Children's Hospital of Philadelphia
3401 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-590-1728
Fax: 215-590-1736
Education:
BS (Biological Chemistry, Cum Laude)
Tulane University, New Orleans, Louisiana, 2007.
MD
St. Louis University School of Medicine, St. Louis, Missouri, 2012.
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Description of Clinical Expertise

Placental pathology
Perinatal pathology

Description of Research Expertise

Placental pathology
Perinatal pathology

Selected Publications

Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kaufman BA, Strauss JF, Parry S, Simmons RA: Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID-19. Journal of Extracellular Vesicles 14(4): e70051, April 2025.

Burrill N, Schindewolf E, Pilchman L, Wright R, Crane H, Gebb J, Khalek N, Soni S, Paidas Teefey C, Oliver ER, Linn R, Moldenhauer JS.: Whole Exome Sequencing in a Population of Fetuses With Structural Anomalies. Prenat Diagn 45(3): 310-317, March 2025.

Coorens THH, Guillaumet-Adkins A, Kovner R, Linn RL, Roberts VHJ, Sule A, Van Hoose PM; dGTEx Consortium. : The human and non-human primate developmental GTEx projects. Nature 637(8046): 557-564, January 2025 Notes: Epub 2025 Jan 15.

Josowitz R, Ho DY, Shankar S, Mondal A, Zavez A, Linn RL, Tian Z, Gaynor JW, Rychik J.: Congenital Heart Disease Fetuses Have Decreased Mid-Gestational Placental Flow, Placental Malperfusion Defects, and Impaired Growth. JACC Adv 4(2): 101559, January 2025.

Cheng K, Seita Y, Whelan EC, Yokomizo R, Hwang YS, Rotolo A, Krantz ID, Ginsberg JP, Kolon TF, Lal P, Luo X, Pierorazio PM, Linn RL, Ryeom S, Sasaki K.: Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline. Cell Reports 43(6): 114323, June 2024 Notes: Epub 2024 Jun 10.

Burrill N, Khalek N, Oliver ER, Linn R, Victoria T, Yates C, Moldenhauer JS.: Case report of fetus with Lowe syndrome: Expanding the prenatal phenotype. Prenat Diagn 44(5): 665-668, May 2024.

Gaynor JW, Moldenhauer JS, Zullo EE, Burnham NB, Gerdes M, Bernbaum JC, D'Agostino JA, Linn RL, Klepczynski B, Randazzo I, Gionet G, Choi GH, Karaj A, Russell WW, Zackai EH, Johnson MP, Gebb JS, Soni S, DeBari SE, Szwast AL, Ahrens-Nicklas RC, Drivas TG, Jacobwitz M, Licht DJ, Vossough A, Nicolson SC, Spray TL, Rychik J, Putt ME.: Progesterone for Neurodevelopment in Fetuses With Congenital Heart Defects: A Randomized Clinical Trial. JAMA Network Open 7(5): e2412291, May 2024.

Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kaufman BA, Strauss JF, Parry S, Simmons RA.: Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19. bioRxiv May 2024.

Fang Bian, Yan Feng, Julia Angel, Rebecca L Linn.: Neonatal Hemochromatosis in a Fetus with De Novo PTEN Mutation: An Autopsy Case Report and Literature Review. Society for pediatric pathology 2024 spring meeting. Baltimore, MD. March 2024.

Josowitz R, Linn R, Rychik J.: The Placenta in Congenital Heart Disease: Form, Function and Outcomes. Neoreviews 24(9): e569-e582, Sep 2023.

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Last updated: 04/30/2025
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