Leonid Roshkovan, MD
Assistant Professor of Clinical Radiology
Active , Phoenixville Hospital
Active Medical Staff, Department of Radiology, Pennsylvania Hospital
Active Medical Staff, Department of Radiology, Penn Presbyterian Medical Center
Attending, Department of Radiology, Hospital of the University of Pennsylvania
Instructor, Department of Radiology, University of Pennsylvania Perelman School of Medicine
Active Medical Staff, Department of Radiology, Chester County Hospital
Department: Radiology
Contact information
Department of Radiology
Hospital of the University of Pennsylvania
1 Silverstein Building, 3400 Spruce Street
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
1 Silverstein Building, 3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-3036
Education:
MD
University of Debrecen, Medical and Health Sciences Centre, Hungary, 2010.
Permanent linkMD
University of Debrecen, Medical and Health Sciences Centre, Hungary, 2010.
Description of Clinical Expertise
Dr. Roshkovan has expertise in thoracic radiology and abdominal imaging with special clinical focus on lung cancer and pleural malignancy.Description of Other Expertise
Selected Research Publications:Berger I, Cengel KA, Simone CB 2nd, Alley EW, Roshkovan L, Haas AR, Patel AM, Khalid U, Culligan MJ, McNulty S, Singhal S, Friedberg JS, Katz SI.: Lymphangitic carcinomatosis: A common radiographic manifestation of local failure following extended pleurectomy/decortication in patients with malignant pleural mesothelioma. Lung Cancer 132: 94-98, Jun 2019.
Roshkovan L, Thompson JC, Katz SI, Deshpande C, Jenkins T, Nowak AK, Francis R, Dennie C, Fabre D, Singhal S, Galperin-Aizenberg M.: Alveolar adenoma of the lung: multidisciplinary case discussion and review of the literature. J Thorac Dis 12: 6847-6853, Nov 2020. PMCID: PMC7711389
Berger I, Simpson S, Friedberg JS, Culligan MJ, Wileyto EP, Alley EW, Sterman D, Patel AM, Khalid U, Simone CB 2nd, Cengel KA, Katz SI, Roshkovan L.: CT for detection of malignant posterior intercostal lymph nodes in patients undergoing pre-operative staging for malignant pleural mesothelioma. Lung Cancer 152: 34-38, Dec 2020.
Patel A, Roshkovan L, McNulty S, Alley E, Torigian DA, Nachiappan AC, Galperin-Aizenberg M, Barbosa EM Jr, DiRienzi J, Berger I, Khalid U, Haas AR, Singhal S, Wileyto EP, Cengel KA, Katz SI.: Delayed-Phase Enhancement for Evaluation of Malignant Pleural Mesothelioma on Computed Tomography: A Prospective Cohort Study. Clin Lung Cancer lin Lung Cancer, 2020.
Roshkovan L, Katz, SI, Berger, I, Friedberg, J, Alley, E, Simone, CB, Haas, A, Cengal, K, Albelda. SM. : "Serum soluble mesothelin-related protein (SMRP) and fibulin-3 levels correlate with malignant pleural mesothelioma (MPM) tumor volumes." Lung Cancer(under review) 2020.
Roshkovan, L, Singhal, S, Katz, SI, and Galperin-Aizenberg, M. : "Clinical Perspectives: Surgicel, an important multimodality imaging mimic of post-operative complication." British Journal of Radiology (under review) 2020.
Roshkovan, L, Thompson, JC, Galperin-Aizenberg, M, Katz, SI. : "Clinical Pearls: A 53 year-old male presents to the emergency department with shortness of breath, cough and fever." Chest (in press) 2020.
Roshkovan, L, Thompson, JC, Galperin-Aizenberg, M, Katz, SI. : "Clinical Pearls: A 53 year-old male presents to the emergency department with shortness of breath, cough and fever." Chest (under review) 2020.
Yousefi, B., Katz, SI, Roshkovan, L. : Invited commentary "Radiomics-AI: A path forward to predicting immunotherapy response for NSCLC" Radiology: Artificial Intelligence(in press) 2020.
Roshkovan L, Litt H.: State-of-the-Art Imaging for the Evaluation of Pulmonary Embolism. Curr Treat Options Cardiovasc Med 20: 71, Aug 2018.
Roshkovan L, Chatterjee N, Galperin-Aizenberg M, Gupta N, Shah R, Barbosa EM Jr, Simpson S, Cook T, Nachiappan A, Knollmann F, Litt H, Desjardins B, Jha S, Panebianco N, Baston C, Thompson JC, Katz SI.: The Role of Imaging in the Management of Suspected or Known COVID-19 Pneumonia: A Multidisciplinary Perspective. Ann Am Thorac Soc nn Am Thorac Soc, 2020.
Description of Research Expertise
Dr. Roshkovan completed a Thoracic Radiology fellowship and Abdominal Imaging fellowship at the University of Pennsylvania Perelman School of Medicine. His primary research focus in developing improved measures of cancer detection and therapy response assessment in thoracic oncology. His work centers on functioning as an active member of an interdisciplinary research team dedicated to advances in thoracic oncology including therapeutic clinical trials and development of novel radiomic signatures for non-small cell therapy response prediction and improving therapy response assessment in NSCLC and mesothelioma.In addition, Dr. Roshkovan is actively engaged in research efforts at the institutional level at Penn as well as the national level where he is an integral part of teams tasked to procure and curate COVID-19 imaging and clinical data so as to accelerate innovation and discovery in improved ways of detecting and characterizing COVID-19 pneumonia. He is also lead in a research project at Penn evaluating utilization of computed tomography (CT) in patients suspected of COVID-19 pneumonia.
He is a member of the Penn Thoracic Oncology Radiomics Working Group, the iMig Pleural Expert Panel and the ACR COVID-19 Registry Steering Committee
Selected Publications
Im JY, Micah N, Perkins AE, Mei K, Geagan M, Roshkovan L, Noël PB.: PixelPrint4D: A 3D Printing Method of Fabricating Patient-Specific Deformable CT Phantoms for Respiratory Motion Applications. Invest Radiol Apr 2025.Iman Yazdani Nia, MD, Lauren Shreve, MD, MBA, Sharyn Katz, MD, MTR, Leonid Roshkovan MD: Advances in the Diagnosis and Management of Subsolid Pulmonary Nodules: Integrating Radiologic, Pathologic, and AI Tools for Optimal Patient Care. Society of Thoracic Radiology meeting March 2025.
Lauren Shreve, MD, MBA, Iman Yazdani Nia, MD, Sharyn Katz1, MD, MTR, Leonid Roshkovan MD: The Many Faces of Pleural Mesothelioma: Review of Radiologic Manifestations of Disease and its Correlation to Pathology, Treatment, and Treatment Response Assessment. Society of Thoracic radiology meting. March 2025.
Stalker M, Walker SL, Lebow E, Pai EL, Watts A, Hwang WT, Banihashemi A, Anderson E, Roshkovan L, Katz SI, Litzky L, Haas AR, Singhal S, Langer CJ, Cengel K, Marmarelis ME.: Incidence and Outcomes of Brain Metastasis in Pleural Mesothelioma in the Era of Immunotherapy. JTO Clin Res Rep 6: 100823, Mar 2025.
K. Mei, L. Roshkovan, S. Sharma, S. Ross, J. Woo, S. S. Halliburton, L. P. Liu, R. Thompson, Z. Yu, P. B. Noël: 3D-printed Anthropomorphic Head Phantom Featuring White and Gray Matter Structures for Evaluating CT Imaging. European Congress of Radiology February 2025.
K. Mei, S. Sharma, L. Roshkovan, S. Ross, N. Akino, L. P. Liu, Z. Yu, S. S. Halliburton, R. Thompson, P. B. Noël. : Photon-counting detector CT imaging of patients with > 95th percentile waist circumference using a 3D-printed pancreas model. European Congress of Radiology February 2025.
Kai Mei, Shobhit Sharma, Leonid Roshkovan, Steven Ross, Hiroshi Moriya, Naruomi Akino, Zhou Yu, Richard Thompson, Peter B. Noël: Characterization of Lung Lesions with Hybrid Lifelike Phantoms in Low-dose Photon-Counting Detector CT. RSNA November 2024.
Kai Mei, Shobhit Sharma, Leonid Roshkovan, Steven Ross, Naruomi Akino, Zhou Yu, Richard Thompson, Peter B. Noël.: Realistic 3D-printed high-resolution CT phantom featuring computational lung lesions for photon-counting CT. RSNA November 2024.
Singh A, Roshkovan L, Horng H, Chen A, Katz SI, Thompson JC, Kontos D.: Radiomics Analysis for the Identification of Invasive Pulmonary Subsolid Nodules From Longitudinal Presurgical CT Scans. J Thorac Imaging 40: e0800, Aug 2024.
Khalaily N, Roshkovan L, Bieber A, Mader R, Brikman S.: The Presence of Diffuse Idiopathic Skeletal Hyperostosis (DISH) among Patients with High Burden of Cardiovascular Risk Factors: A Retrospective Study. Int J Rheumatol 2024: 8877237, Jul 2024.