Description of Clinical Expertise

Dr. Roshkovan has expertise in thoracic radiology and abdominal imaging with special clinical focus on lung cancer and pleural malignancy.

Description of Other Expertise

Selected Research Publications:

Berger I, Cengel KA, Simone CB 2nd, Alley EW, Roshkovan L, Haas AR, Patel AM, Khalid U, Culligan MJ, McNulty S, Singhal S, Friedberg JS, Katz SI.: Lymphangitic carcinomatosis: A common radiographic manifestation of local failure following extended pleurectomy/decortication in patients with malignant pleural mesothelioma. Lung Cancer 132: 94-98, Jun 2019.

Roshkovan L, Thompson JC, Katz SI, Deshpande C, Jenkins T, Nowak AK, Francis R, Dennie C, Fabre D, Singhal S, Galperin-Aizenberg M.: Alveolar adenoma of the lung: multidisciplinary case discussion and review of the literature. J Thorac Dis 12: 6847-6853, Nov 2020. PMCID: PMC7711389

Berger I, Simpson S, Friedberg JS, Culligan MJ, Wileyto EP, Alley EW, Sterman D, Patel AM, Khalid U, Simone CB 2nd, Cengel KA, Katz SI, Roshkovan L.: CT for detection of malignant posterior intercostal lymph nodes in patients undergoing pre-operative staging for malignant pleural mesothelioma. Lung Cancer 152: 34-38, Dec 2020.

Patel A, Roshkovan L, McNulty S, Alley E, Torigian DA, Nachiappan AC, Galperin-Aizenberg M, Barbosa EM Jr, DiRienzi J, Berger I, Khalid U, Haas AR, Singhal S, Wileyto EP, Cengel KA, Katz SI.: Delayed-Phase Enhancement for Evaluation of Malignant Pleural Mesothelioma on Computed Tomography: A Prospective Cohort Study. Clin Lung Cancer lin Lung Cancer, 2020.

Roshkovan L, Katz, SI, Berger, I, Friedberg, J, Alley, E, Simone, CB, Haas, A, Cengal, K, Albelda. SM. : "Serum soluble mesothelin-related protein (SMRP) and fibulin-3 levels correlate with malignant pleural mesothelioma (MPM) tumor volumes." Lung Cancer(under review) 2020.

Roshkovan, L, Singhal, S, Katz, SI, and Galperin-Aizenberg, M. : "Clinical Perspectives: Surgicel, an important multimodality imaging mimic of post-operative complication." British Journal of Radiology (under review) 2020.

Roshkovan, L, Thompson, JC, Galperin-Aizenberg, M, Katz, SI. : "Clinical Pearls: A 53 year-old male presents to the emergency department with shortness of breath, cough and fever." Chest (in press) 2020.

Roshkovan, L, Thompson, JC, Galperin-Aizenberg, M, Katz, SI. : "Clinical Pearls: A 53 year-old male presents to the emergency department with shortness of breath, cough and fever." Chest (under review) 2020.

Yousefi, B., Katz, SI, Roshkovan, L. : Invited commentary "Radiomics-AI: A path forward to predicting immunotherapy response for NSCLC" Radiology: Artificial Intelligence(in press) 2020.

Roshkovan L, Litt H.: State-of-the-Art Imaging for the Evaluation of Pulmonary Embolism. Curr Treat Options Cardiovasc Med 20: 71, Aug 2018.

Roshkovan L, Chatterjee N, Galperin-Aizenberg M, Gupta N, Shah R, Barbosa EM Jr, Simpson S, Cook T, Nachiappan A, Knollmann F, Litt H, Desjardins B, Jha S, Panebianco N, Baston C, Thompson JC, Katz SI.: The Role of Imaging in the Management of Suspected or Known COVID-19 Pneumonia: A Multidisciplinary Perspective. Ann Am Thorac Soc nn Am Thorac Soc, 2020.

Description of Research Expertise

Dr. Roshkovan completed a Thoracic Radiology fellowship and Abdominal Imaging fellowship at the University of Pennsylvania Perelman School of Medicine. His primary research focus in developing improved measures of cancer detection and therapy response assessment in thoracic oncology. His work centers on functioning as an active member of an interdisciplinary research team dedicated to advances in thoracic oncology including therapeutic clinical trials and development of novel radiomic signatures for non-small cell therapy response prediction and improving therapy response assessment in NSCLC and mesothelioma.

In addition, Dr. Roshkovan is actively engaged in research efforts at the institutional level at Penn as well as the national level where he is an integral part of teams tasked to procure and curate COVID-19 imaging and clinical data so as to accelerate innovation and discovery in improved ways of detecting and characterizing COVID-19 pneumonia. He is also lead in a research project at Penn evaluating utilization of computed tomography (CT) in patients suspected of COVID-19 pneumonia.

He is a member of the Penn Thoracic Oncology Radiomics Working Group, the iMig Pleural Expert Panel and the ACR COVID-19 Registry Steering Committee