Hayley M. Knollman, M.D.
Assistant Professor of Clinical Medicine (Hematology-Oncology)
Attending, Hospital of the University of Pennsylvania
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
10th Floor, South Pavilion
Philadelphia, PA 19104
3400 Civic Center Blvd
10th Floor, South Pavilion
Philadelphia, PA 19104
Education:
BS (Chemistry )
Purdue University , 2006.
MD
Indiana University School of Medicine, 2010.
Permanent linkBS (Chemistry )
Purdue University , 2006.
MD
Indiana University School of Medicine, 2010.
Selected Publications
Jung W, Hubbard RA, Smith AM, Ko K, Huang A, Wang J, Isaacs JM, Zhang L, Liu PP, Chen Z, Shah PD, Mintzer D, Bhattacharya S, Knollman HM, Clark AS, Koropeckyj-Cox D, Messinger M, Wilcox NS, Xia C, Narayan V, Upshaw JN, Armenian SH, Ky B.: Risk-guided cardioprotection with carvedilol in patients with breast cancer (CCT guide): a phase 1 randomized clinical trial. Breast Cancer Res Treat June 2025.Berlin E, Ko K, Ma L, Messing I, Hollawell C, Smith AM, Taunk NK, Narayan V, Upshaw JN, Clark AS, Shah PD, Knollman H, Bhattacharya S, Koropeckyj-Cox D, Wang J, Yegya-Raman N, Han IS, Lefebvre B, Li T, Wilcox NS, Jung W, Chen J, Freedman GM, Ky B.: Cardiac Effects of Modern Breast Radiation Therapy in Patients Receiving Systemic Cancer Therapy. JACC CardioOncol April 2025.
Julia Tchou, Amy Clark, Neil Taunk, Gary Freedman, Nucleus Xu, Andy Minn, Angela Bradbury, Angela Demichele Gross, Susan Domchek, Hayley Knollman, Rachel Jankowitz, Payal Shah, Oluwadamilola Fayanju, Anupma Nayak, Joseph Fraietta and Alexander Huang: Major pathologic response after a single radiotherapy fraction + a single pembrolizumab dose given preoperatively in patients with cT1N0 triple negative breast cancer (TNBC) – preliminary results of a phase 1b/2 study (NCT04454528). Journal for ImmunoTherapy of Cancer, Society for Immunotherapy of Cancer, Denver, CO 10: A674-A674, March 2023 Notes: "Poster Presentation"
Alexandra Torres; Carey Kokkonen; Mary Oladeji; Kurt D'Andrea; Rosemarie Mick; Vivek Narayan; Michael Mallamaci; Gayle Ewing; Hayley Knollman; Nadine M. Tung; Mark Robson; Katherine L. Nathanson; Susan Domchek; Payal D. Shah: Harnessing olaparib, palbociclib, and endocrine therapy (HOPE): Phase I/II trial of olaparib, palbociclib and fulvestrant in patients with BRCA1/2-associated, hormone receptor-positive, HER2-negative metastatic breast cancer San Antonio Breast Cancer Symposium, San Antonio, TX. 82, February 2022 Notes: "Poster Presentation"
Lauren Bayne; Isoris Nivar; Brooke Goodspeed; Shannon Deluca; E. Paul Wileyto; Natalie Shih; Anupma Nayak; Michael D Feldman; Joshua Edwards; Kevin Fox; Jennifer M. Matro; Susan Domchek; Hayley Knollman; Rachel Jankowitz; Angela Bradbury; Payal D. Shah; Jewell Graves; George Woodfield; Elizabeth Chislock; Jianping Wang; George Belka; Lewis A. Chodosh; Amy S. Clark; Angela DeMichele: Identifying breast cancer survivors with dormant disseminated tumor cells: The PENN-SURMOUNT screening study. Cancer Research, San Antonio Breast Cancer Symposium, San Antonio, TX. 81, December 2021 Notes: "Poster Presentation"
Igor Makhlin; Amy S Clark; Paul Wileyto; Noah Goodman; John Ndicu; Shannon DeLuca; Candace Clark; S. William Stavropoulos; Natalie Shih; Michael D Feldman; Susan M Domchek; Jennifer M Matro; Payal D Shah; Hayley M Knollman; Kevin R Fox; Kara N Maxwell; Lewis A Chodosh; Angela DeMichele: Investigating the clinical utility of tumor mutational burden in predicting rapid progression and death in patients with metastatic breast cancer. Cancer Research/San Antonio Breast Cancer Symposium, San Antonio, TX. 81, December 2021 Notes: "Poster Presentation"
Biniyam G.Demissei, Srinath Adusumalli, Rebecca A.Hubbard, Srinivas Denduluri, Vivek Narayan, Amy S. Clark, Payal Shah, Hayley Knollman, Kelly D. Getz, Richard Aplenc, Joseph R. Carver, Bonnie Ky: Cardiology Involvement in Patients With Breast Cancer Treated With Trastuzumab. JACC CardioOncology 2(2): 179-189, June 2020.
Biniyam G. Demissei, Rebecca A. Hubbard, Liyong Zhang, Amanda M. Smith, Karyn Sheline, Caitlin McDonald, Vivek Narayan, Susan M. Domchek, Angela DeMichele, Payal Shah, Amy S. Clark, Kevin Fox, Jennifer Matro, Angela R. Bradbury, Hayley Knollman, Kelly D. Getz, Saro H. Armenian, James L. Januzzi, W. H. Wilson Tang, Peter Liu, and Bonnie Ky: Changes in Cardiovascular Biomarkers with Breast Cancer Therapy and Associations with Cardiac Dysfunction. Journal of the American Heart Association 9(2): e014708. January 2020.
West AH1,2, Knollman H3, Dugan J4, Hedeker D5, Handorf EA6, Nielsen SM1,2, Bealin LC3, Goldblatt LG3, Willems H4, Daly MB3, Afghahi A4, Olopade OI1,2, Hulick PJ7, Shagisultanova E4, Huo D1,5, Obeid E3, Churpek JE1,2.: Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study. Cancer Medicine 8(12): 5609-5618, September 2019.
ES McDonald; S Carlin; KN Maxwell; A Nayak; RK Doot; AR Pantel; MD Farwell; DA Pryma; AS Clark; P Shah; AM DeMichele; A Ziober; EK Schubert; K Palmer; HS Lee; J Matro; L de la Cruz; J Tchou; DN Anderson; MD Feldman; RE Sheffer; H Knollman; MD Schnall; M Makvandi; S Domchek; RA Hubbard; RH Mach; DA Mankoff: PET imaging of PARP-1 expression in breast cancer. Cancer Research 79, February 2019.