Nicholas K. Brown, PhD, F(ACHI)
Associate Professor of Clinical Pathology and Laboratory Medicine
Associate Director, Histocompatibility Testing Laboratory, Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine
Contact information
Founders 7019
3400 Spruce Street
Philadelphia, PA 19104
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-7789
Publications
Education:
BA (Biology)
Kalamazoo College, Kalamazoo, MI, 2000.
PhD (Immunology and Microbiology (incl. Research Assistant role))
Wayne State University School of Medicine, Detroit, MI, 2007.
Permanent linkBA (Biology)
Kalamazoo College, Kalamazoo, MI, 2000.
PhD (Immunology and Microbiology (incl. Research Assistant role))
Wayne State University School of Medicine, Detroit, MI, 2007.
Selected Publications
N.K. Brown, L. Gragert, A.N. Paynter, K. McCullough, ... M. Kamoun: Donor specific antibodies to DQ antigens are rare in DR antigen matched kidney transplants. Human Immunology 85(Supplement), September 2024 Notes: Article 110940.A.N. Paynter, M. Kamoun, N.K. Brown, R.J. Urbanowicz, ... L. Gragert: Profiling performance of high-resolution HLA imputation with complementary metrics and visualizations using an open-source validation framework. Human Immunology 85(supplement), September 2024 Notes: Article 110922.
N.K. Brown, R. Bray, G. Morris, L. Gragert: Reporting HLA antigens for the DRB3/4/5 Locus at the first field in UNet would decrease rates of deceased donor offer refusal. Human Immunology 85(Supplement), September 2024 Notes: Article 110919.
Olga A. Timofeeva and Nicholas K. Brown: The ASHI Standards for Accredited Laboratories: How and Why They Change. ASHI Quarterly. American Society of Histocompatibility and Immunogenetics. Q3: 26-32, September 2024.
McCullough K., Gragert L., Urbanowicz R., Brown N., Kamoun M.: Interaction between HLA-DRB1 and DQB1 Antigen Mismatches as Predictors of Kidney Allograft Failure. American Journal of Transplantation 24(6, Supplement 1): A115, June 2024.
Nicholas K. Brown and Chang Liu: HLA-DQ Associated Autoimmunity. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q2 2024: 10-14, June 2024.
Nicholas K. Brown: The Data Standards Hackathons (DaSH) for Next Generation Sequencing. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q1 2024: 8-12, March 2024.
Misra MK, Brown NK, Marino SG.: Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA 103(2), Feb 2024 Notes: doi: 10.1111/tan.15368.
D. Bell, M. Personius, V. McCarro, T. Bui, N. Brown: The DRB4*03:01N allele confounds NGS typing software. Human Immunology 84(Supplement): P109, September 2023.
E. Kamieniecki, N. Brown: An R program for automatic quality control of single antigen bead assays via Levey-Jennings charts. Human Immunology 84(Supplement): P116, September 2023.