Nicholas K. Brown, PhD, F(ACHI)
Associate Professor of Clinical Pathology and Laboratory Medicine
Associate Director, Histocompatibility Testing Laboratory, Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine
Contact information
Founders 7019
3400 Spruce Street
Philadelphia, PA 19104
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-7789
Publications
Education:
BA (Biology)
Kalamazoo College, Kalamazoo, MI, 2000.
PhD (Immunology and Microbiology (incl. Research Assistant role))
Wayne State University School of Medicine, Detroit, MI, 2007.
Permanent linkBA (Biology)
Kalamazoo College, Kalamazoo, MI, 2000.
PhD (Immunology and Microbiology (incl. Research Assistant role))
Wayne State University School of Medicine, Detroit, MI, 2007.
Selected Publications
Misra MK, Brown NK, Marino SG.: Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA 103(2), Feb 2024 Notes: doi: 10.1111/tan.15368.D. Bell, M. Personius, V. McCarro, T. Bui, N. Brown: The DRB4*03:01N allele confounds NGS typing software. Human Immunology 84(Supplement): P109, September 2023.
L. Gragert, K. Lindblad, C. Jett, M. Mankowski, M. Mangiola, D. Stewart, G.P. Morris, J. Lunz, N. Brown : Estimating rates of immunologically incompatible organ offers caused by use of antigen-level deceased donor HLA typing for allocation. Human Immunology 84(Supplement): 021, September 2023.
E. Kamieniecki, N. Brown: An R program for automatic quality control of single antigen bead assays via Levey-Jennings charts. Human Immunology 84(Supplement): P116, September 2023.
Dasariraju S, Gragert L, Wager GL, McCullough K, Brown NK, Kamoun M, Urbanowicz RJ: HLA Amino Acid Mismatch-Based Risk Stratification of Kidney Allograft Failure Using a Novel Machine Learning Algorithm. J Biomed Inform 142: 104374, June 2023.
Brown NK, Peyster EG, Bui T: R for HLA Data: A Suite of Tools for Managing and Analyzing Data from Clinical HLA Laboratory Information Systems. American Journal of Transplantation 23(6, supplement 1): S756, June 2023.
Potluri V, Naqvi F, Goldberg DS, Shah M, Loupy A, Abt P, Blumberg E, Trofe-Clark J, Bloom R, Sawinski D, Chattergoon M, Segev DL, Bair-Marcantoni N, Durand CM, Reddy R, Levine M, Brown N, Mapchan S, Aubert O, Desai N, Reese PP: Longer-Term Clinical Outcomes From the THINKER and EXPANDERTrials of Transplantation of HCV-RNA+ Donor Kidneys Into Hepatitis C Virus-Negative Recipients. Kidney International Reports April 2023.
Brown, NK: Carving your path through ASHI: An interview with Dr. Nicholas Brown. Coffee & Compatibility Podcast April 2023.
Nicholas Brown, Thanh-Mai Bui: An open-source program to gather relevant data for virtual crossmatch. Human Immunology 83(S1): P145, November 2022.
F. Brad Johnson, Sandra Mateu, Edward Vo, Jane Kearns, Thanh-Mai Bui, Nicholas Brown, Malek Kamoun: An unusually well HLA-matched pairing between a homozygous HLA-A*03:02 deceased donor kidney and a highly sensitized patient carrying HLA-A*03:02 and having antibodies to HLA-A*03:01. Human Immunology 83(S1): P33, November 2022.