Nicholas K. Brown, PhD, F(ACHI)

faculty photo
Associate Professor of Clinical Pathology and Laboratory Medicine
Associate Director, Histocompatibility Testing Laboratory, Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine

Contact information
Founders 7019
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-7789
BA (Biology)
Kalamazoo College, Kalamazoo, MI, 2000.
PhD (Immunology and Microbiology (incl. Research Assistant role))
Wayne State University School of Medicine, Detroit, MI, 2007.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Dasariraju S, Gragert L, Wager GL, McCullough K, Brown NK, Kamoun M, Urbanowicz RJ: HLA Amino Acid Mismatch-Based Risk Stratification of Kidney Allograft Failure Using a Novel Machine Learning Algorithm. J Biomed Inform 142: 104374, June 2023.

Brown NK, Peyster EG, Bui T: R for HLA Data: A Suite of Tools for Managing and Analyzing Data from Clinical HLA Laboratory Information Systems. American Journal of Transplantation 23(6, supplement 1): S756, June 2023.

Potluri V, Naqvi F, Goldberg DS, Shah M, Loupy A, Abt P, Blumberg E, Trofe-Clark J, Bloom R, Sawinski D, Chattergoon M, Segev DL, Bair-Marcantoni N, Durand CM, Reddy R, Levine M, Brown N, Mapchan S, Aubert O, Desai N, Reese PP: Longer-Term Clinical Outcomes From the THINKER and EXPANDERTrials of Transplantation of HCV-RNA+ Donor Kidneys Into Hepatitis C Virus-Negative Recipients. Kidney International Reports April 2023.

Brown, NK: Carving your path through ASHI: An interview with Dr. Nicholas Brown. Coffee & Compatibility Podcast April 2023.

Nicholas Brown, Thanh-Mai Bui: An open-source program to gather relevant data for virtual crossmatch. Human Immunology 83(S1): P145, November 2022.

F. Brad Johnson, Sandra Mateu, Edward Vo, Jane Kearns, Thanh-Mai Bui, Nicholas Brown, Malek Kamoun: An unusually well HLA-matched pairing between a homozygous HLA-A*03:02 deceased donor kidney and a highly sensitized patient carrying HLA-A*03:02 and having antibodies to HLA-A*03:01. Human Immunology 83(S1): P33, November 2022.

Nicholas Brown: Applying modern data science tools to aid virtual crossmatch. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q3 2022: 32-35, September 2022 Notes: No issue.

Wang X, Liu M, Zhang J, Brown NK, Zhang P, Zhang Y, Liu H, Du X, Wu W, Devenport M, Tao W, Mao-Draayer Y, Chen GY, Chen YE, Zheng P, Liu Y.: CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. Cell Metab 34(8): 1088-1103, Aug 2022.

Kamoun M, Askar M, Kearns JD, Bui TM, Nguyen M, Brown NK, Duquesnoy RJ.: Immunogenetics of heteroclitic recognition of HLA-DQB1 55R eplet specificity by human alloantibody. Human Immunology 83(2): 99-106, Feb 2022.

Nicholas Brown, David Porter, Alison Loren, Malek Kamoun, F.Brad Johnson: An HLA-identical child as a donor for hematopoietic cell transplantation: is this a haploidentical or matched-“sibling” transplant? Human Immunology 82(S1): P05, September 2021.

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Last updated: 07/31/2023
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