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Nicholas K. Brown, PhD, F(ACHI)
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Associate Professor of Clinical Pathology and Laboratory Medicine
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Associate Director, Histocompatibility Testing Laboratory, Hospital of the University of Pennsylvania
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Department: Pathology and Laboratory Medicine
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Contact information
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Founders 7019
35 3400 Spruce Street
Philadelphia, PA 19104
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35 3400 Spruce Street
Philadelphia, PA 19104
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Office: 215-615-7789
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Publications
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Links
b3 Search PubMed for articles
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b3 Search PubMed for articles
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Education:
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39 Kalamazoo College, Kalamazoo, MI, 2000.
21 8 PhD 48 (Immunology and Microbiology (incl. Research Assistant role)) c
4f Wayne State University School of Medicine, Detroit, MI, 2007.
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Permanent link21 7 BA 14 (Biology) c
39 Kalamazoo College, Kalamazoo, MI, 2000.
21 8 PhD 48 (Immunology and Microbiology (incl. Research Assistant role)) c
4f Wayne State University School of Medicine, Detroit, MI, 2007.
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1ad Ho S, Hod-Dvorai R, Bravo-Egana V, Kheradmand T, Bishop C, Brown NK, Eilrich H, O'Shields EF, Houp JA, Sanfilippo AM, Timofeeva O; American Society for Histocompatibility and Immunogenetics (ASHI) Professional Standards Division.: Practical guide to personnel competency assessment in clinical histocompatibility laboratories. Hum Immunol 86(4), July 2025.
12f N.K. Brown, L. Gragert, A.N. Paynter, K. McCullough, ... M. Kamoun: Donor specific antibodies to DQ antigens are rare in DR antigen matched kidney transplants. Human Immunology 85(Supplement), September 2024 Notes: Article 110940.
166 A.N. Paynter, M. Kamoun, N.K. Brown, R.J. Urbanowicz, ... L. Gragert: Profiling performance of high-resolution HLA imputation with complementary metrics and visualizations using an open-source validation framework. Human Immunology 85(supplement), September 2024 Notes: Article 110922.
13a N.K. Brown, R. Bray, G. Morris, L. Gragert: Reporting HLA antigens for the DRB3/4/5 Locus at the first field in UNet would decrease rates of deceased donor offer refusal. Human Immunology 85(Supplement), September 2024 Notes: Article 110919.
120 Olga A. Timofeeva and Nicholas K. Brown: The ASHI Standards for Accredited Laboratories: How and Why They Change. ASHI Quarterly. American Society of Histocompatibility and Immunogenetics. Q3: 26-32, September 2024.
135 McCullough K., Gragert L., Urbanowicz R., Brown N., Kamoun M.: Interaction between HLA-DRB1 and DQB1 Antigen Mismatches as Predictors of Kidney Allograft Failure. American Journal of Transplantation 24(6, Supplement 1): A115, June 2024.
f0 Nicholas K. Brown and Chang Liu: HLA-DQ Associated Autoimmunity. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q2 2024: 10-14, June 2024.
107 Nicholas K. Brown: The Data Standards Hackathons (DaSH) for Next Generation Sequencing. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q1 2024: 8-12, March 2024.
101 Misra MK, Brown NK, Marino SG.: Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA 103(2), Feb 2024 Notes: doi: 10.1111/tan.15368.
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Selected Publications
e2 Nicholas K. Brown: HLA Testing for Celiac Disease. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q3: 20-24, September 2025.1ad Ho S, Hod-Dvorai R, Bravo-Egana V, Kheradmand T, Bishop C, Brown NK, Eilrich H, O'Shields EF, Houp JA, Sanfilippo AM, Timofeeva O; American Society for Histocompatibility and Immunogenetics (ASHI) Professional Standards Division.: Practical guide to personnel competency assessment in clinical histocompatibility laboratories. Hum Immunol 86(4), July 2025.
12f N.K. Brown, L. Gragert, A.N. Paynter, K. McCullough, ... M. Kamoun: Donor specific antibodies to DQ antigens are rare in DR antigen matched kidney transplants. Human Immunology 85(Supplement), September 2024 Notes: Article 110940.
166 A.N. Paynter, M. Kamoun, N.K. Brown, R.J. Urbanowicz, ... L. Gragert: Profiling performance of high-resolution HLA imputation with complementary metrics and visualizations using an open-source validation framework. Human Immunology 85(supplement), September 2024 Notes: Article 110922.
13a N.K. Brown, R. Bray, G. Morris, L. Gragert: Reporting HLA antigens for the DRB3/4/5 Locus at the first field in UNet would decrease rates of deceased donor offer refusal. Human Immunology 85(Supplement), September 2024 Notes: Article 110919.
120 Olga A. Timofeeva and Nicholas K. Brown: The ASHI Standards for Accredited Laboratories: How and Why They Change. ASHI Quarterly. American Society of Histocompatibility and Immunogenetics. Q3: 26-32, September 2024.
135 McCullough K., Gragert L., Urbanowicz R., Brown N., Kamoun M.: Interaction between HLA-DRB1 and DQB1 Antigen Mismatches as Predictors of Kidney Allograft Failure. American Journal of Transplantation 24(6, Supplement 1): A115, June 2024.
f0 Nicholas K. Brown and Chang Liu: HLA-DQ Associated Autoimmunity. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q2 2024: 10-14, June 2024.
107 Nicholas K. Brown: The Data Standards Hackathons (DaSH) for Next Generation Sequencing. ASHI Quarterly. American Society for Histocompatibility and Immunogenetics, Q1 2024: 8-12, March 2024.
101 Misra MK, Brown NK, Marino SG.: Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA 103(2), Feb 2024 Notes: doi: 10.1111/tan.15368.
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