Jonathan Schug

faculty photo
Adjunct Assistant Professor of Genetics
Department: Genetics

Contact information
12-156 Smilow Center for Translational Research
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: 215 898 0773
Lab: 215 898 0772
BA (Mathematics)
University of Pennsylvania, 1980.
MSE (Computer and Information Science)
University of Pennsylvania, 1995.
PhD (Computer and Information Science)
University of Pennsylvania, 2005.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Wang YJ, Traum D, Schug J, Gao L, Liu C; HPAP Consortium, Atkinson MA, Powers AC, Feldman MD, Naji A, Chang KM, Kaestner KH.: Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes. Cell Metabolism. Cell Press, 29: 1-5, January 2019.

Condon, D. E., Tran, P. V., Lien, Y. C., Schug, J., Georgieff, M. K., Simmons, R. A., Won, K. J.: Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus. BMC Bioinformatics 19(1): 31, 2018.

Serr, I., Scherm, M. G., Zahm, A. M., Schug, J., Flynn, V. K., Hippich, M., Kalin, S., Becker, M., Achenbach, P., Nikolaev, A., Gerlach, K., Liebsch, N., Loretz, B., Lehr, C. M., Kirchner, B., Spornraft, M., Haase, B., Segars, J., Kuper, C., Palmisano, R., Waisman, A., Willis, R. A., Kim, W. U., Weigmann, B., Kaestner, K. H., Ziegler, A. G., Daniel, C.: A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes. Sci Transl Med 10(422), 2018.

Nam, K. N., Wolfe, C. M., Fitz, N. F., Letronne, F., Castranio, E. L., Mounier, A., Schug, J., Lefterov, I., Koldamova, R.: Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice. Biochim Biophys Acta 1864(1): 152-161, 2018.

Gazala, S. A., Horwitz, E., Ben-Haroush Schyr, R., Bardugo, A., Israeli, H., Hija, A., Schug, J., Shin, S., Dor, Y., Kaestner, K. H., Ben-Zvi, D.: Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity. Diabetes 2018.

Castranio, E. L., Mounier, A., Wolfe, C. M., Nam, K. N., Fitz, N. F., Letronne, F., Schug, J., Koldamova, R., Lefterov, I.: Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury. Neurobiol Dis 105: 1-14, 2017.

Nam, K. N., Mounier, A., Wolfe, C. M., Fitz, N. F., Carter, A. Y., Castranio, E. L., Kamboh, H. I., Reeves, V. L., Wang, J., Han, X., Schug, J., Lefterov, I., Koldamova, R.: Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer''s model mice. Sci Rep 7(1): 4307, 2017.

Li, C., Ackermann, A. M., Boodhansingh, K. E., Bhatti, T. R., Liu, C., Schug, J., Doliba, N., Han, B., Cosgrove, K. E., Banerjee, I., Matschinsky, F. M., Nissim, I., Kaestner, K. H., Naji, A., Adzick, N. S., Dunne, M. J., Stanley, C. A., De Leon, D. D.: Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets. Diabetes 66(7): 1901-1913, 2017.

Lahens, N. F., Ricciotti, E., Smirnova, O., Toorens, E., Kim, E. J., Baruzzo, G., Hayer, K. E., Ganguly, T., Schug, J., Grant, G. R.: A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression. BMC Genomics 18(1): 602, 2017.

Galivo, F., Benedetti, E., Wang, Y., Pelz, C., Schug, J., Kaestner, K. H., Grompe, M.: Reprogramming human gallbladder cells into insulin-producing beta-like cells. PLoS One 12(8): e0181812, 2017.

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Last updated: 03/01/2019
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