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Noam A. Cohen, M.D., PhD
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Ralph Butler Endowed Professor for Medical Research
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Director, Rhinology Research, University of Pennsylvania, Department of Otorhinolaryngology
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Department: Otorhinolaryngology: Head and Neck Surgery
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Graduate Group Affiliations
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- Pharmacology e
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Contact information
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UPHS, Department of ORL:HNS
44 3400 Spruce Street, 5 Ravdin
Philadelphia, PA 19104-4283
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44 3400 Spruce Street, 5 Ravdin
Philadelphia, PA 19104-4283
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Email:
cohenn@uphs.upenn.edu
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cohenn@uphs.upenn.edu
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Publications
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Education:
21 9 B.A. 14 (Biology) c
32 Johns Hopkins University , 1990.
21 a Ph.D. 19 (Neuroscience) c
32 Johns Hopkins University , 1998.
21 9 M.D. 15 (Medicine) c
32 Johns Hopkins University , 1998.
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Permanent link21 9 B.A. 14 (Biology) c
32 Johns Hopkins University , 1990.
21 a Ph.D. 19 (Neuroscience) c
32 Johns Hopkins University , 1998.
21 9 M.D. 15 (Medicine) c
32 Johns Hopkins University , 1998.
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1e Airway taste receptors
22 Respiratory cilia function
24 respiratory mucosal biofilms
1d Chronic Rhinosinusitis
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21 Paranasal sinus disorders
2e Endoscopic Sinus and Skull Base Surgery
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Description of Research Expertise
35 Upper airway mucosal innate immunity1e Airway taste receptors
22 Respiratory cilia function
24 respiratory mucosal biofilms
1d Chronic Rhinosinusitis
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Description of Clinical Expertise
27 Chronic Rhinosinusitis21 Paranasal sinus disorders
2e Endoscopic Sinus and Skull Base Surgery
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194 Lee RJ, Xiong G, Kofonow JM, Chen B, Lysenko A, Jiang P, Abraham V, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Beauchamp GK, Paschalis-Thomas D, Ischriopoulos H, Kriendler JL, Reed DR, Cohen NA: T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest 122(11): 4145-59, Nov 2012.
15a Lee RJ, Kofonow JM, Rosen PL, Siebert AP, Chen B, Doghramji L, Xiong G, Adappa ND, Palmer JN, Kennedy DW, Kreindler JL, Margolskee RF, Cohen NA: Bitter and sweet taste receptor regulation of human upper respiratory innate immunity. J Clin Invest 124(3): 1393-405, Mar 2014.
114 Lee RJ, Workman AD, Carey RM, Chen B, Rosen PL, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Cohen NA: Fungal Aflatoxins Reduce Respiratory Mucosal Ciliary Function. Nat Sci Rep 14(6): 33221, Sep 2016.
157 Adappa ND, Farquhar D, Palmer JN, Kennedy DW, Doghramji L, Morris SA, Owens D, Mansfield C, Lysenko A, Lee RJ, Cowart BJ, Reed DR, Cohen NA: TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis. Int Forum Allergy Rhinol 6(1): 25-33, Jan 2016.
cb Stevens WW, Lee RJ, Schleimer RP, Cohen NA: Chronic rhinosinusitis pathogenesis. J Allergy Clin Immunol 136(6): 1442-53, Dec 2015.
14a Adappa AD, Howland TJ, Palmer JN, Kennedy DW, Doghramji L, Lysenko A, Reed DR, Lee RJ, Cohen NA: Genetics of the Taste Receptor T2R38 Correlates with Chronic Rhinosinusitis Necessitating Surgical Intervention. Int Forum Allergy Rhinol 3(3): 184-7, Mar 2013.
161 Adappa AD, Zhang Z, Palmer JN, Kennedy DW, Doghramji L, Lysenko A, Reed DR, Scott T, Zhao NW, Owens D, Lee RJ, Cohen NA: The Bitter Taste Receptor T2R38 is an Independent Risk Factor for Chronic Rhinosinusitis Requiring Sinus Surgery. Int Forum Allergy Rhinol 4(1): 3-7, Jan 2014.
15b Adappa ND, Truesdale CM, Workman AD, Doghramji L, Mansfield C, Kennedy DW, Palmer JN, Cowart BJ, Cohen NA: Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients. Int Forum Allergy Rhinol 6(8): 783-91, Aug 2016.
104 Douglas JE, Saunders CJ, Reed DR, Cohen NA : A role for airway taste receptor modulation in the treatment of upper respiratory infections. Expert Rev Respir Med 10(2): 157-70, Feb 2016.
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Selected Publications
ab Lee, R.J., Cohen, N.A.: Bitter Taste Bodyguards. Scientific American 314(2): 38-43, February 2016.194 Lee RJ, Xiong G, Kofonow JM, Chen B, Lysenko A, Jiang P, Abraham V, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Beauchamp GK, Paschalis-Thomas D, Ischriopoulos H, Kriendler JL, Reed DR, Cohen NA: T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest 122(11): 4145-59, Nov 2012.
15a Lee RJ, Kofonow JM, Rosen PL, Siebert AP, Chen B, Doghramji L, Xiong G, Adappa ND, Palmer JN, Kennedy DW, Kreindler JL, Margolskee RF, Cohen NA: Bitter and sweet taste receptor regulation of human upper respiratory innate immunity. J Clin Invest 124(3): 1393-405, Mar 2014.
114 Lee RJ, Workman AD, Carey RM, Chen B, Rosen PL, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Cohen NA: Fungal Aflatoxins Reduce Respiratory Mucosal Ciliary Function. Nat Sci Rep 14(6): 33221, Sep 2016.
157 Adappa ND, Farquhar D, Palmer JN, Kennedy DW, Doghramji L, Morris SA, Owens D, Mansfield C, Lysenko A, Lee RJ, Cowart BJ, Reed DR, Cohen NA: TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis. Int Forum Allergy Rhinol 6(1): 25-33, Jan 2016.
cb Stevens WW, Lee RJ, Schleimer RP, Cohen NA: Chronic rhinosinusitis pathogenesis. J Allergy Clin Immunol 136(6): 1442-53, Dec 2015.
14a Adappa AD, Howland TJ, Palmer JN, Kennedy DW, Doghramji L, Lysenko A, Reed DR, Lee RJ, Cohen NA: Genetics of the Taste Receptor T2R38 Correlates with Chronic Rhinosinusitis Necessitating Surgical Intervention. Int Forum Allergy Rhinol 3(3): 184-7, Mar 2013.
161 Adappa AD, Zhang Z, Palmer JN, Kennedy DW, Doghramji L, Lysenko A, Reed DR, Scott T, Zhao NW, Owens D, Lee RJ, Cohen NA: The Bitter Taste Receptor T2R38 is an Independent Risk Factor for Chronic Rhinosinusitis Requiring Sinus Surgery. Int Forum Allergy Rhinol 4(1): 3-7, Jan 2014.
15b Adappa ND, Truesdale CM, Workman AD, Doghramji L, Mansfield C, Kennedy DW, Palmer JN, Cowart BJ, Cohen NA: Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients. Int Forum Allergy Rhinol 6(8): 783-91, Aug 2016.
104 Douglas JE, Saunders CJ, Reed DR, Cohen NA : A role for airway taste receptor modulation in the treatment of upper respiratory infections. Expert Rev Respir Med 10(2): 157-70, Feb 2016.
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