Jane Elizabeth Minturn, M.D., Ph.D.

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Clinical Professor of Pediatrics (Oncology)
Assistant Physician in Oncology, Division of Oncology, The Children's Hospital of Philadelphia
Full Member-Pediatric Oncology Research Program, Abramson Cancer Center of the University of Pennsylvania
Cancer Center Liaison, Global Patient Services, Children's Hospital of Philadelphia
Director of Clinical Operations, Neuro-Oncology Section, Children’s Hospital of Philadelphia
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Oncology, HUB 3590
3500 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-426-5026
Fax: 215-590-3296
Education:
B.S. (Psychobiology)
University of Southern California, 1986.
M.Phil. (Philosophy)
Yale University, 1993.
M.D. (Medicine)
Yale University School of Medicine, 1996.
Ph.D. (Neurobiology)
Yale University, 1996.
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Description of Research Expertise

Early phase clinical trial development in pediatric central nervous system tumors.
Understanding neuro-cognitive late effects in children treated for brain tumors in infancy
Understanding caregiver challenges of young adult survivors of childhood brain tumors

Description of Clinical Expertise

Developmental Therapeutics in Pediatric Brain Tumors.
Late Effects in Survivors of Pediatric Brain Tumors

Description of Other Expertise

Division of Oncology Clinical Liaison, Department of Global Patient Services Program, The Children's Hospital of Philadelphia

Selected Publications

Das A, Tabori U, Sambira Nahum LC, Collins NB, Deyell R, Dvir R, Faure-Conter C, Hassall TE, Minturn JE, Edwards M, Brookes E, Bianchi V, Levine A, Stone SC, Sudhaman S, Sanchez-Ramirez S, Ercan AB, Stengs L, Chung J, Negm L, Getz G, Maruvka YE, Ertl-Wagner B, Ohashi PS, Pugh T, Hawkins C, Bouffet E, Morgenstern DA. : Efficacy of nivolumab in pediatric cancers with high mutation burden and mismatch-repair deficiency. Clin Cancer Res 29(23): 4770, December 2023.

Haas-Kogan DA, Aboian MS, Minturn JE, Leary SES, Abdelbaki MS, Goldman S, Elster JD, Kraya A, Lueder MR, Ramakrishnan D, von Reppert M, Liu KX, Rokita JL, Resnick AC, Solomon DA, Phillips JJ, Prados M, Molinaro AM, Waszak SM, Mueller S: Everolimus for Children with Recurrent or Progressive Low-Grade Glioma: Results from the Phase II PNOC001 Trial. J Clin Oncol Nov 2023.

Kotch C, Elgarten C, Wilhelm D, Schmus, McWhorter J, Li Y, Minturn JE: The impact of proactive gastrostomy tube placement on treatment-related outcomes in young children with high-grade central nervous system tumors. Journal Pediatric Pediatric Hematology and Oncology 45(6): 333, August 2023.

Gubbiotti MA, Madsen P, Abdullaev Z, Aldape K, Shekdar K, Yang A, Minturn JE, Santi M, Viaene AN: ZFTA-fused supratentorial ependymoma with novel fusion partner, DUX4. J Neuropathol Exp Neurol 82(7): 668, June 2023.

Kotch C, Wagner K, Harris Broad J, Dombi E, Minturn JE, Phillips P, Smith K, Li Y, Jacobs IN, Elden LM, Fisher MJ, Belasco J. : Vinblastine/methotrexate for debilitating and progressive plexiform neurofibroma in children and young adults with neurofibromatosis type 1: A Phase 2 Study. Cancers 15(9): 2621, May 2023.

Bartlett AL, Lane A, Chaney B, Escorza NY, Black K, Cochrane A, Minturn J, Bartels U, Warren K, Hansford J, Ziegler D, Diez B, Goldman S, Packer R, Kieran M, DeWire-Schottmiller M, Erker C, Monje Deisseroth M, Wagner L, Koschmann C, Dorris K, Shih CS, Hassall T, Samson Y, Fisher P, Wang SS, Tsui K, Sevlever G, Zhu X, Dexheimer P, Asher A, Fuller C, Drissi R, Jones B, Leach J, Fouladi M.: Characteristics of children <36 months of age with DIPG: A report from the international DIPG registry. Neuro Oncol 24(12): 2190, December 2022.

Hocking MC, Schultz RT, Minturn JE, Brodsky C, Albee M, Herrington JD: Reduced fusiform gyrus activation during face processing in pediatric brain tumor survivors. J Int Neuropsychol Soc Page: 937, Oct 2022.

Lazow MA, Nievelstein MT, Lane A, Bandopadhayhay P, DeWire-Schottmiller M, Fouladi M, Glod JW, Greiner RJ, Hoffman LM, Hummel TR, Kilburn L, Leary S, Minturn JE, Packer R, Ziegler DS, Chaney B, Black K, de Blank P, Leach JL: Volumetric endpoints in diffuse intrinsic pontine glioma: comparison to cross-sectional measures and outcome correlations in the International DIPG/DMG Registry. Neuro Oncol 24(9): 1598, Sep 2022.

Devine KJ, Diorio C, Richman SA, Henderson AA, Oranges K, Armideo E, Kolb MS, Freedman JL, Aplenc R, Fisher MJ, Minturn JE, Olson T, Bagatell R, Barakat L, Croy C, Mauro J, Vitlip L, Acord MR, Mattei P, Johnson VK, Devine CM, Pasquariello C, Reilly AF.: Guideline for Children with Cancer Receiving General Anesthesia for Procedures and Imaging. J Pediatr Hematol Oncol 44(4): e859, May 2022.

Lazow MA, Fuller C, DeWire M, Lane A, Bandopadhayay P, Bartels U, Bouffet E, Cheng S, Cohen KJ, Cooney TM, Coven SL, Dholaria H, Diez B, Dorris K, El-Ayadi M, El-Sheikh A, Fisher PG, Fonseca A, Lombardi MG, Greiner RJ, Goldman S, Gottardo N, Gururangan S, Hansford JR, Hassall T, Hawkins C, Kilburn L, Koschmann C, Leary SE, Ma J, Minturn JE, Monje-Deisseroth M, Packer R, Samson Y, Sandler ES, Sevlever G, Tinkle CL, Tsui K, Wagner LM, Zaghloul M, Ziegler DS, Chaney B, Black K, Asher A, Drissi R, Fouladi M, Jones BV, Leach JL : Accuracy of Central Neuro-imaging Review of DIPG Compared with Histopathology in the International DIPG Registry. Neuro Oncol 24(5), May 2022.

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Last updated: 03/12/2024
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