Tapan Ganguly, Ph.D.

faculty photo
Adjunct Professor of Genetics
Director, DNA Sequencing Facility, Department of Genetics, University of Pennsylvania School of Medicine
Director, Cell Center Services, Department of Genetics, University of Pennsylvania School of Medicine
Director, Penn Genomic Analysis Core, Perelman School of Medicine
Department: Genetics

Contact information
B16 Anat-Chem Building
3620 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-7238
Lab: 215-573-7407
B.Sc. (Physics)
Presidency College, Calcutta University, India, 1974.
M.Sc. (Physics with Biophysics Major)
Calcutta University , 1977.
Ph.D. (Physics/Biophysics)
Calcutta University, 1985.
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Description of Research Expertise

Mutational analysis of disease causing genes using several approaches
Next-gen sequencing technologies and its various applications
Genomics studies using whole genome and targeted DNA and RNA profiling

Selected Publications

Lahens Nicholas F, Ricciotti Emanuela, Smirnova Olga, Toorens Erik, Kim Eun Ji, Baruzzo Giacomo, Hayer Katharina E, Ganguly Tapan, Schug Jonathan, Grant Gregory R: A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression. BMC genomics 18(1): 602, Aug 2017.

N. Lahens, E. Ricciotti, E. J. Kim, G. Baruzzo, K. Hayer, T. Ganguly, J. Schug, G. Grant: A comparison of Illumina and Ion Torrent platforms in a study of differential gene expression. ISMB 2016, Orlando, Florida 2016.

Lao Z, Kelly CJ, Yang XY, Jenkins WT, Toorens E, Ganguly T, Evans SM, Koch CJ.: Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA. PloS one. 10(7): e0133895, July 2015.

Del Portillo A, Lagana SM, Yao Y, Uehara T, Jhala N, Ganguly T, Nagy P, Gutierrez J, Luna A, Abrams J, Liu Y, Brand R, Sepulveda JL, Falk GW, Sepulveda AR.: Evaluation of Mutational Testing of Preneoplastic Barrett's Mucosa by Next-Generation Sequencing of Formalin-Fixed, Paraffin-Embedded Endoscopic Samples for Detection of Concurrent Dysplasia and Adenocarcinoma in Barrett's Esophagus. The Journal of Molecular Diagnostics 17(4): 412-9, Jul 2015.

Ewens Kathryn G, Kanetsky Peter A, Richards-Yutz Jennifer, Purrazzella Juliana, Shields Carol L, Ganguly Tapan, Ganguly Arupa: Chromosome 3 status combined with BAP1 and EIF1AX mutation profiles are associated with metastasis in uveal melanoma. Investigative ophthalmology & visual science 55(8): 5160-7, Jun 2014.

Shoar Zohreh, Ganguly Tapan, Anderson Carol E, De Luca Francesco, Suarez Elizabeth: Absence of WNT4 gene mutation in a patient with MURCS association. Journal of pediatric endocrinology & metabolism : JPEM 27(5-6): 555-9, May 2014.

Margolis David J, Gupta Jayanta, Apter Andrea J, Ganguly Tapan, Hoffstad Ole, Papadopoulos Maryte, Rebbeck Tim R, Mitra Nandita: Filaggrin-2 variation is associated with more persistent atopic dermatitis in African American subjects. The Journal of allergy and clinical immunology 133(3): 784-9, Mar 2014.

Chen Zhao, Moran Kimberly, Richards-Yutz Jennifer, Toorens Erik, Gerhart Daniel, Ganguly Tapan, Shields Carol L, Ganguly Arupa: Enhanced sensitivity for detection of low-level germline mosaic RB1 mutations in sporadic retinoblastoma cases using deep semiconductor sequencing. Human mutation 35(3): 384-91, Mar 2014.

Ganguly Tapan, Chen Peiqin, Teetsel Rebecca, Zhang Lan Ping, Papaioannou Elias, Cianciarulo Joseph: High-throughput sequencing of high copy number plasmids from bacterial cultures by heat lysis. BioTechniques 39(3): 304, 306, 308, Sep 2005.

Ganguly Arupa, Dunbar Tanya, Chen Peiqin, Godmilow Lynn, Ganguly Tapan: Exon skipping caused by an intronic insertion of a young Alu Yb9 element leads to severe hemophilia A. Human genetics 113(4): 348-52, Sep 2003.

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Last updated: 08/17/2017
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