Christos Coutifaris, M.D., Ph.D.

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Celso-Ramon Garcia Professor
Attending Physician, Hospital of the University of Pennsylvania
Member, Center for Research in Reproduction and Women's Health, University of Pennsylvania
Director, Fellowship Program in Reproductive Endocrinology and Infertility Approved by the American Board of Obstetrics and Gynecology and ACGME, Penn Medicine
Member, Cancer Center , University of Pennsylvania
Chair, Department of Ob/Gyn Committee on Appointments and Promotions, OBGYN, UPHS
Diversity Search Advisor, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania
Education Officer, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania
Vice Chair for Faculty Development, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania
Director, Endocrine Laboratory, CAP Accredited, Division of Reproductive Endocrinology and Infertility, Penn Medicine
Department: Obstetrics and Gynecology

Contact information
Division of Reproductive Endocrinology and Infertility
Department of Obstetrics and Gynecology
3701 Market Street, Suite 800
Philadelphia, PA 19104
Office: 215-662-3378
A.B. (Biophysics)
Amherst College, 1976.
M.D. (Medicine)
University of Pennsylvania, 1982.
Ph.D. (Anatomy; Reproductive Neuroendocrinology)
University of Pennsylvania, 1984.

Executive Training Course for Department Chairs and Division Chiefs of Obstetrics and Gynecology, The Wharton School, University of Pennsylvania , 1998.
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Selected Publications

Mani S, Ghosh J, Rhon-Calderon EA, Lan Y, Ord T, Kalliora C, Chan J, Schultz B, Vaughan-Williams E, Coutifaris C, Sapienza C, Senapati S, Bartolomei MS, Mainigi M.: Embryo Cryopreservation leads to sex-specific DNA methylation perturbations in both human and mouse placentas. Hum Mol Genet. Page: Online ahead of print. Jun 2022.

Legro RS, Hansen KR, Diamond MP, Steiner AZ, Coutifaris C, Cedars MI, Hoeger KM, Usadi R, Johnstone EB, Haisenleder DJ, Wild RA, Barnhart KT, Mersereau J, Trussell JC, Krawetz SA, Kris-Etherton PM, Sarwer DB, Santoro N, Eisenberg E, Huang H, Zhang H; Reproductive Medicine Network.: Effects of preconception lifestyle intervention in infertile women with obesity: The FIT-PLESE randomized controlled trial. PLoS Med. 19(1): e1003883, Jan 2022.

Richardson H, Kalliora C, Mainigi M, Coutifaris C, Sammel MD, Senapati S.: Impact of mode of conception on early pregnancy human chorionic gonadotropin rise and birth weight. F S Rep. 3(3): 13-19, Dec 2021.

Eisenberg E, Legro RS, Diamond MP, Huang H, O'Brien LM, Smith YR, Coutifaris C, Hansen KR, Santoro N, Zhang H.: Sleep Habits of Women With Infertility. J Clin Endocrinol Metab. 106(11): e4414-e4426, Oct 2021.

Barnhart KT, Hansen KR, Stephenson MD, Usadi R, Steiner AZ, Cedars MI, Jungheim ES, Hoeger KM, Krawetz SA, Mills B, Alston M, Coutifaris C, Senapati S, Sonalkar S, Diamond MP, Wild RA, Rosen M, Sammel MD, Santoro N, Eisenberg E, Huang H, Zhang H; Reproductive Medicine Network.: Effect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial. JAMA 326(5): 390-400, Aug 2021.

Steinberg Weiss M, Roe AH, Allison KC, Dodson WC, Kris-Etherton PM, Kunselman AR, Stetter CM, Williams NI, Gnatuk CL, Estes SJ, Sarwer DB, Coutifaris C, Legro RS, Dokras A.: Lifestyle modifications alone or combined with hormonal contraceptives improve sexual dysfunction in women with polycystic ovary syndrome. Fertil Steril 115(2), Feb 2021.

Shah A, Dodson WC, Kris-Etherton PM, Kunselman AR, Stetter CM, Gnatuk CL, Estes SJ, Allison KC, Sarwer DB, Sluss PM, Coutifaris C, Dokras A, Legro RS.: Effects of Oral Contraception and Lifestyle Modification on Incretins and TGF-ß Superfamily Hormones on PCOS. J Clin Endocrinol Metab 106(1), Jan 2021.

Engmann L, Sun F, Legro RS, Diamond MP, Zhang H, Santoro N; Reproductive Medicine Network.: Factors associated with study protocol adherence and bio banking participation in reproductive medicine clinical trials and their relationship to live birth. Human Reprod 35(12), Dec 2020.

Vitek W, Sun F, Hoeger KM, Santoro N, Diamond MP, Zhang H, Legro RS; Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network.: Short-term weight change and live birth among women with unexplained infertility and polycystic ovary syndrome undergoing ovulation induction. Fertil Steril 114(5), November 2020.

Sullivan-Pyke C, Mani S, Rhon-Calderon EA, Ord T, Coutifaris C, Bartolomei MS, Mainigi M.: Timing of exposure to gonadotropins has differential effects on the conceptus: evidence from a mouse model. Biol Reprod 103(4), Oct 2020.

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Last updated: 07/27/2022
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