Lou J. Soslowsky, Ph.D.

faculty photo
Fairhill Professor
Director of Orthopaedic Research, University of Pennsylvania
Director of Basic Science Research, Shoulder and Elbow Service, University of Pennsylvania
Vice Chair for Research, Department of Orthopaedic Surgery, University of Pennsylvania (reappointed 2009, 2024)
Fellow, Institute of Aging, University of Pennsylvania
Founding Director, Penn Center for Musculoskeletal Disorders, University of Pennsylvania (Type 1 center designation in 2008)
Executive Committee, University of Pennsylvania, Department of Bioengineering
Executive Committee, Department of Bioengineering, University of Pennsylvania
Associate Dean for Research Integration, University of Pennsylvania, Perelman School of Medicine
Department: Orthopaedic Surgery
Graduate Group Affiliations
Contact information
McKay Orthopaedic Research Laboratory
307A Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8654
Fax: 215-573-2133
Email: soslowsk@upenn.edu
Publications

Search PubMed for articles
Links
Search PubMed for articles
 McKay Orthopaedic Research Laboratory
Penn Center for Musculoskeletal Disorders
Lou Soslowsky Lab Homepage
Education:
Diploma
East Brunswick High School , 1982.
 B.S. (Engineering Mechanics)
Columbia University, 1986.
 M.S. (Engineering Mechanics)
Columbia University, 1987.
 M.Phil
Columbia University, 1989.
 Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
 Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
Permanent link
 
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Description of Research Expertise

orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow

Selected Publications

Ye Y, Shetye SS, Birk DE, Soslowsky LJ.: Regulatory Role of Collagen XI in the Establishment of Mechanical Properties of Tendons and Ligaments in Mice Is Tissue Dependent. J Biomech Eng 147: 011003, Jan 2025.

 Cohen JS, Fung AK, Stein MK, Darrieutort-Laffite C, Weiss SN, Shetye SS, Thurlow NA, Nuss CA, Dyment NA, Soslowsky LJ.: Tendon-targeted knockout of collagen XI disrupts patellar and Achilles tendon structure and mechanical properties during murine postnatal development. Connect Tissue Res Dec 2024.

 Darrieutort-Laffite C, Weiss SN, Nuss CA, Newton JB, Eekhoff JD, Soslowsky LJ.: Decorin Knockdown Improves Aged Tendon Healing by Enhancing Recovery of Viscoelastic Properties, While Biglycan May Not. Ann Biomed Eng Nov 2024.

 Panebianco CJ, Azar TF, Duffy MP, Nijsure MP, Sharp E, Tamburro MK, Hast M, Shore EM, Mauck RL, Soslowsky LJ, Shuda JR, Gullbrand SE.: Learning on a Limb: An outreach module to engage high school students in orthopaedics. J Orthop Res Nov 2024.

 Leahy TP, Chenna SS, Soslowsky LJ, Dyment NA.: Focal adhesion kinase regulates tendon cell mechanoresponse and physiological tendon development. FASEB J Sep 2024.

 Newton JB, Nuss CA, Weiss SN, Betts RL, Sehgal CM, Soslowsky LJ.: In Vivo Photoacoustic Ultrasound (PAUS) Assay for Monitoring Tendon Collagen Compositional Changes during Injury and Healing. Diagnostics (Basel) 14: 1498, Jul 2024.

 Fung AK, Li Y, Wang J, Leahy TP, Shetye S, Liu XS, Soslowsky LJ: Long-Term effects of reproduction and lactation on the rat supraspinatus tendon and proximal humerus. J Biomech Eng 146(6): 060905, Jun 2024.

 Carlson JA, Shetye SS, Sun M, Weiss SN, Birk DE, Soslowsky LJ: Collagen V haploinsufficiency in female murine patellar tendons results in altered matrix engagement and cellular density, demonstrating decreased healing. J Orthop Res 42(5): 950-60, May 2024.

 Beach ZM, Nuss CA, Weiss SN, Soslowsky LJ: Neonatal Achilles Tendon Microstructure is Negatively Impacted by Decorin and Biglycan Knockdown After Injury and During Development. Ann Biomed Eng 52(3): 657-70, Mar 2024.

 Darrieutort-Laffite C, Blanchard F, Soslowsky LJ, Le Goff B: Biology and physiology of tendon healing. Joint Bone Spine 91(5): 105696, Feb 2024.
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Last updated: 12/20/2024
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