Stephen J. Schuster, M.D.
Robert and Margarita Louis-Dreyfus Professor in Chronic Lymphocytic Leukemia and Lymphoma Clinical Care and Research
Attending Physician, Department of Medicine, Division of Hematology-Oncology, Hospital of the University of Pennsylvania
Director, Lymphoma Translational Research, Abramson Cancer Center of the University of Pennsylvania
Department: Medicine
Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-178
3400 Civic Center Blvd
Philadelphia, PA 19104
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-178
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: (215) 349-5330
Fax: 215-615-5888
Fax: 215-615-5888
Publications
Education:
B.S. (Psychology)
Saint Joseph's University, Philadelphia, PA, 1976.
Laboratory Research Technician, Division of Rheumatology, Hahnemann Medical College and Hospital, Philadelphia, PA, 1977.
M.D.
Jefferson Medical College, Philadelphia, PA, 1981.
Permanent linkB.S. (Psychology)
Saint Joseph's University, Philadelphia, PA, 1976.
Laboratory Research Technician, Division of Rheumatology, Hahnemann Medical College and Hospital, Philadelphia, PA, 1977.
M.D.
Jefferson Medical College, Philadelphia, PA, 1981.
Selected Publications
Omar Elghawy, Austin G Yang, Jonathan H Sussman, Colin J Thomas, Jordan S Carter, Daniel J Landsburg, Jakub Svoboda, Ellen Kim, Alain H Rook, Jina Chung, Jennifer Villasenor-Park, John P Plastaras, Michael LaRiviere, Harper Hubbeling, Monica Chelius, Sunita D Nasta, Elise A Chong, Stephen J Schuster, Stefan K Barta.: Retrospective Cohort Study of Novel Oral Agents Lenalidomide and Duvelisib For Relapsed or Refractory Mycosis Fungoides and Sézary Syndrome. J Am Acad Dermatol. Nov 16 2024 Notes: doi: 10.1016/j.jaad.2024.10.095. Online ahead of print.Daniel J Landsburg, Jennifer J D Morrissette, Sunita D Nasta, Stefan K Barta, Stephen J Schuster, Elise A Chong, Jakub Svoboda, Ashley Barlev, Adam Bagg, Salvatore F Priore.: Genomic Features of Newly Diagnosed Large B-cell Lymphoma with or without Subsequent Disease Progression. Cancer Res Commun. 4(11): 2947-2954, Nov 1 2024 Notes: doi: 10.1158/2767-9764.CRC-24-0337.
Nausheen Ahmed, William Wesson, Forat Lutfi, David L Porter, Veronika Bachanova, Loretta J Nastoupil, Miguel-Angel Perales, Richard T Maziarz, Jamie Brower, Gunjan L Shah, Andy I Chen, Olalekan O Oluwole, Stephen J Schuster, Michael R Bishop, Joseph P McGuirk, Peter A Riedell.: Optimizing the post-CAR T monitoring period in recipients of axicabtagene ciloleucel, tisagenlecleucel, and lisocabtagene maraleucel. Blood Adv. 8(20): 5346-5354, Oct 22 2024 Notes: doi: 10.1182/bloodadvances.2023012549.
Omar Elghawy, Miao Cao, Jason Xu, Daniel J Landsburg, Jakub Svoboda, Sunita D Nasta, Elise A Chong, Stephen J Schuster, Colin J Thomas, Jordan S Carter, Montreh Tavakkoli, Marco Ruella, Stefan K Barta.: Prevalence and Prognostication of CD5+ Mature T-Cell Lymphomas. Cancers (Basel). 16(19): 3430, Oct 9 2024 Notes: doi: 10.3390/cancers16193430.
Laurie H Sehn, Nancy L Bartlett, Matthew J Matasar, Stephen J Schuster, Sarit E Assouline, Pratyush Giri, John Kuruvilla, Mazyar Shadman, Chan Y Cheah, Sascha Dietrich, Keith Fay, Matthew Ku, Loretta J Nastoupil, Michael C Wei, Shen Yin, Iris To, Derrick Kaufman, Antonia Kwan, Elicia Penuel, Christopher R Bolen, Lihua Elizabeth Budde.: Long-term 3-year follow-up of mosunetuzumab in relapsed or refractory follicular lymphoma after ≥2 prior therapies. Blood. Oct 24 2024 Notes: Online ahead of print. doi: 10.1182/blood.2024025454.
Michael Schneider, Sunita D Nasta, Stefan K Barta, Elise A Chong, Jakub Svoboda, Stephen J Schuster, Daniel J Landsburg.: Analysis of Histologic, Immunohistochemical and Genomic Features of Large B Cell Lymphoma Tumors May Predict Response to Polatuzumab Vedotin Based Therapy in Patients With Relapsed/Refractory Disease. Clin Lymphoma Myeloma Leuk. Sep 6 2024 Notes: doi: 10.1016/j.clml.2024.08.010. Online ahead of print.
Nektarios Kostopoulos, Francesca Costabile, Elisavet Krimitza, Silvia Beghi, Denisa Goia, Renzo Perales-Linares, George Thyfronitis, Michael J LaRiviere, Elise A Chong, Stephen J Schuster, Amit Maity, Constantinos Koumenis, John P Plastaras, Andrea Facciabene.: Local Radiation Enhances Systemic CAR T Cell Efficacy by Augmenting Antigen Cross-Presentation and T-cell Infiltration. Blood Adv. Aug 30 2024 Notes: Online ahead of print. doi: 10.1182/bloodadvances.2024012599.
Ruchi P Patel, Guido Ghilardi, Yunlin Zhang, Yi-Hao Chiang, Wei Xie, Puneeth Guruprasad, Ki Hyun Kim, Inkook Chun, Mathew G Angelos, Raymone Pajarillo, Seok Jae Hong, Yong Gu Lee, Olga Shestova, Carolyn Shaw, Ivan Cohen, Aasha Gupta, Trang Vu, Dean Qian, Steven Yang, Aditya Nimmagadda, Adam E Snook, Nicholas Siciliano, Antonia Rotolo, Arati Inamdar, Jaryse Harris, Ositadimma Ugwuanyi, Michael Wang, Alberto Carturan, Luca Paruzzo, Linhui Chen, Hatcher J Ballard, Tatiana Blanchard, Chong Xu, Mohamed Abdel-Mohsen, Khatuna Gabunia, Maria Wysocka, Gerald P Linette, Beatriz Carreno, David M Barrett, David T Teachey, Avery D Posey, Daniel J Powell Jr, C Tor Sauter, Stefano Pileri, Vinodh Pillai, John Scholler, Alain H Rook, Stephen J Schuster Stefan K Barta, Patrizia Porazzi, Marco Ruella.: CD5 deletion enhances the antitumor activity of adoptive T cell therapies. Sci Immunol. 9(97), Jul 19 2024 Notes: doi: 10.1126/sciimmunol.adn6509.
Rahul S Bhansali, Fredrik Ellin, Thomas Relander, Miao Cao, Wenrui Li, Qi Long, Nivetha Ganesan, Robert Stuver, Steven M Horwitz, Kitsada Wudhikarn, Steven R Hwang, N Nora Bennani, Julio Chavez, Lubomir Sokol, Hayder Saeed, Frank Duan, Pierluigi Porcu, Priyanka Pullarkat, Neha Mehta-Shah, Jasmine M Zain, Miguel Ruiz, Jonathan E Brammer, Rishab Prakash, Swaminathan P Iyer, Adam J Olszewski, Ajay Major, Peter A Riedell, Sonali M Smith, Caroline Goldin, Bradley Haverkos, Bei Hu, Tony Z Zhuang, Pamela B Allen, Wael Toama, Murali Janakiram, Taylor R Brooks, Deepa Jagadeesh, Nisha Hariharan, Aaron M Goodman, Gabrielle Hartman, Paola Ghione, Fatima Fayyaz, Joanna M Rhodes, Elise A Chong, James N Gerson, Daniel J Landsburg, Sunita D Nasta, Stephen J Schuster, Jakub Svoboda, Mats Jerkeman, Stefan K Barta: The CNS relapse in T-cell lymphoma index predicts CNS relapse in patients with T- and NK-cell lymphomas. Blood Adv. 8(13): 3507-3518, Jul 9 2024 Notes: doi: 10.1182/bloodadvances.2024012800.
Puneeth Guruprasad, Alberto Carturan, Yunlin Zhang, Jong Hyun Cho, Kingsley Gideon Kumashie, Ruchi P Patel, Ki-Hyun Kim, Jong-Seo Lee, Yoon Lee, Jong Hoon Kim, Junho Chung, Akshita Joshi, Ivan Cohen, Maksim Shestov, Guido Ghilardi, Jaryse Harris, Raymone Pajarillo, Mathew Angelos, Yong Gu Lee, Shan Liu, Jesse Rodriguez, Michael Wang, Hatcher J Ballard, Aasha Gupta, Ositadimma H Ugwuanyi, Seok Jae Albert Hong, Audrey C Bochi-Layec, Christopher T Sauter, Linhui Chen, Luca Paruzzo, Shane Kammerman, Olga Shestova, Dongfang Liu, Laura A Vella, Stephen J Schuster, Jakub Svoboda, Patrizia Porazzi, Marco Ruella: The BTLA-HVEM axis restricts CAR T cell efficacy in cancer. Nat Immunol. 25(6): 1020-1032, Jun 2024 Notes: doi: 10.1038/s41590-024-01847-4.