Stephen J. Schuster, M.D.
Robert and Margarita Louis-Dreyfus Professor in Chronic Lymphocytic Leukemia and Lymphoma Clinical Care and Research
Attending Physician, Department of Medicine, Division of Hematology-Oncology, Hospital of the University of Pennsylvania
Director, Lymphoma Translational Research, Abramson Cancer Center of the University of Pennsylvania
Department: Medicine
Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-178
3400 Civic Center Blvd
Philadelphia, PA 19104
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-178
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: (215) 349-5330
Fax: 215-615-5888
Fax: 215-615-5888
Publications
Education:
B.S. (Psychology)
Saint Joseph's University, Philadelphia, PA, 1976.
Laboratory Research Technician, Division of Rheumatology, Hahnemann Medical College and Hospital, Philadelphia, PA, 1977.
M.D.
Jefferson Medical College, Philadelphia, PA, 1981.
Permanent linkB.S. (Psychology)
Saint Joseph's University, Philadelphia, PA, 1976.
Laboratory Research Technician, Division of Rheumatology, Hahnemann Medical College and Hospital, Philadelphia, PA, 1977.
M.D.
Jefferson Medical College, Philadelphia, PA, 1981.
Selected Publications
Furqan, Fateeha. Ahn, Kwang W. Kaur, Manmeet. Patel, Jinalben. Ansell, Stephen. Awan, Farrukh T. Baird, John. Bezerra, Evandro. Farooq, Umar. Fung, Henry. Khurana, Arushi. Lekakis , Lazaros. Lutfi, Forat. McCarty, John. Mukherjee, Akash. Nath, Rajneesh. Romancik, Jason. Schuster, Stephen J. Smith, Melody. Winter, Allison. Turtle, Cameron. Sauter, Craig. Shadman, Mazyar. Herrar, Alex. Hamadani, Mehdi.: Autologous Transplant or CAR-T as Consolidation Options in MYC Rearranged Large B-Cell Lymphoma Patients in Remission After Salvage Treatments. Am J Hematol. 100(7): 1152-1162, Jul 2025 Notes: doi: 10.1002/ajh.27687.Yegya-Raman, Nikhil. Plastaras, John P. Wright, Christopher M. Chelius, Monica R. Zhang, Siqi. Baron, Jonathan A. Hubbeling, Harper. Sim, Austin J. Robinson, Timothy J. Jain, Michael D. Imber, Brandon S. Fregonese, Beatrice. Yahalom, Joachim. Ladbury, Colton. Dandapani, Savita. Pinnix, Chelsea C. Gunther, Jillian R. Fang, Penny Q. Wu, Susan Y. Dabaja, Bouthaina S. Yang, Joanna C. Chew, Jessica. Braunstein, Steve. Sinha, Sumi. Denlinger, Nathan. Sun, Susan. Terezakis, Stephanie A. Sakthivel, Gukan. Constine, Louis S. Chowdhry, Amit K. Reagan, Patrick M. Burke, Skyler. Tseng, Yolanda D. LaRiviere, Michael J. Maity, Amit. Schuster, Stephen J. Chong, Elise A. Figura, Nicholas B.: Bridging Radiotherapy Prior to Chimeric Antigen Receptor T-Cells for B-Cell Lymphomas: An ILROG Multicenter Study. Blood Adv. 9(13): 3293-3303, Jul 8 2025 Notes: doi: 10.1182/bloodadvances.2025015855.
Elghawy, Omar. Wang, Julia. Leung, Olivia J. Swami, Nishwant. Carvajal, Veronica. Yang, Guang. Landsburg, Daniel J. Svoboda, Jakub. Nasta, Sunita D. Chong, Elise A. Schuster, Stephen J. Thomas, Colin J. Carter, Jordan S. Bagg, Adam. Barta, Stefan K.: Clinical Impact of Next-Generation Sequencing of T-Cell Lymphomas: A Single Institution Experience. Clin Lymphoma Myeloma Leuk. 25(7): 505-511, Jul 2025 Notes: doi: 10.1016/j.clml.2025.01.017.
Elghawy, Omar. Sussman, Jonathan H. Yang, Austin G. Thomas, Colin J. Carter, Jordan S. Landsburg, Daniel J. Svoboda, Jakub. Kim, Ellen. Rook, Alain H. Chung, Jina. Plastaras, John P. LaRiviere, Michael. Hubbeling, Harper. Chelius, Monica. Nasta, Sunita D. Chong, Elise A. Schuster, Stephen J. Barta, Stefan K.: Pembrolizumab in Relapsed or Refractory Mycosis Fungoides or Sézary Syndrome. JAMA Dermatol. 161(6): 656-658, Jun 1 2025 Notes: doi: 10.1001/jamadermatol.2025.0251.
Lϋӧnd, Fabiana. Whalen, Jeanne. Song, Youngchul. Schriefer, Kalyn. Newcombe, Rick. Orlando, Elena J. Choi, Sarah M. Ruella, Marco. Fraietta, Joseph A. Schuster, Stephen J. Brogdon, Jennifer L. Niederst, Matthew J. Treanor, Louise M.: DLBCL cells emerge post CD19 CAR-T with cross-antigen resistance and a gene signature predictive of clinical CAR-T response. Blood Cancer Discov. Jun 27 2025 Notes: doi: 10.1158/2643-3230.BCD-24-0176. Online ahead of print.
Awasthi, Rakesh. Grupp, Stephan A. Waldron, Edward. Yanik, Gregory A. Tam, Constantine S. Rives, Susana. McGuirk, Joseph P. Pulsipher, Michael A. Jaeger, Ulrich. Myers, Gary Douglas. Borchmann, Peter. Schuster, Stephen J. Stefanski, Heather E. Bishop, Michael R. Chakraborty, Abhijit. Masood, Aisha. Baruchel, André. Waller, Edmund K.: Evaluation of In vivo CAR Transgene Levels in Tisagenlecleucel-Treated Patients with Relapsed/Refractory B-ALL and DLBCL. Blood Adv. Jun 24 2025 Notes: doi: 10.1182/bloodadvances.2024014995. Online ahead of print.
Svoboda, Jakub. Landsburg, Daniel J. Gerson, James. Nasta, Sunita D. Barta, Stefan K. Chong, Elise A. Cook, Michael. Frey, Noelle V. Shea, Joanne. Cervini, Amanda. Marshall, Amy. Four, Megan. Davis, Megan M. Jadlowsky, Julie K. Chew, Anne. Pequignot, Edward. Gonzalez, Vanessa. Noll, Julia Han. Paruzzo, Luca. Rojas-Levine, Juliana. Plesa, Gabriela. Scholler, John. Siegel, Donald L. Levine, Bruce L. Porter, David L. Ghassemi, Saba. Ruella, Marco. Rech, Andrew. Leskowitz, Rachel M. Fraietta, Joseph A. Hwang, Wei-Ting. Hexner, Elizabeth. Schuster, Stephen J. June, Carl H.: Enhanced CAR T-Cell Therapy for Lymphoma after Previous Failure. N Engl J Med. 392(18): 1824-1835, May 8 2025 Notes: doi: 10.1056/NEJMoa2408771.
Jadlowsky, Julie K. Hexner, Elizabeth O. Marshall, Amy. Grupp, Stephan A. Frey, Noelle V. Riley, James L. Veloso, Elizabeth. McConville, Holly. Rogal, Walter. Czuczman, Cory. Hwang, Wei-Ting. Li, Yimei. Leskowitz, Rachel M. Farrelly, Olivia. Karar, Jayashree. Christensen, Shannon. Barber-Rotenberg, Julie. Gaymon, Avery. Aronson, Naomi. Bernstein, Wendy. Melenhorst, Jan Joseph. Roche, Aoife M. Everett, John K. Zolnoski, Sonja A. McFarland, Alexander G. Reddy, Shantan. Petrichenko, Angelina. Cook, Emma J. Lee, Carole. Gonzalez, Vanessa E. Alexander, Kathleen. Kulikovskaya, Irina. Ramírez-Fernández, Ángel. Minehart, Janna C. Ruella, Marco. Gill, Saar I. Schuster, Stephen J. Cohen, Adam D. Garfall, Alfred L. Shah, Payal D. Porter, David L. Maude, Shannon L. Levine, Bruce L. Siegel, Donald L. Chew, Anne. McKenna, Stephen. Lledo, Lester. Davis, Megan M. Plesa, Gabriela. Herbst, Friederike. Stadtmauer, Edward A. Tebas, Pablo. DiNofia, Amanda. Haas, Andrew. Haas, Naomi B. Myers, Regina. O'Rourke, Donald M. Svoboda, Jakub. Tanyi, Janos L. Aplenc, Richard. Jacobson, Jeffrey M. Ko, Andrew H. Cohen, Roger B. June, Carl H. Bushman, Frederic D. Fraietta, Joseph A.: Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nat Med. 31(4): 1134-1144, Apr 2025 Notes: doi: 10.1038/s41591-024-03478-6.
Ni, Vincent. Nasta, Sunita D. Barta, Stefan K. Schuster, Stephen J. Chong, Elise A. Svoboda, Jakub. Morrissette, Jennifer J D. Barlev, Ashley. Bagg, Adam. Priore, Salvatore F. Landsburg, Daniel J. : Identification of a clinicopathologic prognostic index for newly diagnosed large B-cell lymphoma patients treated with R-CHOP. Haematologica. 110(4): 1023-1027, Apr 1 2025 Notes: doi: 10.3324/haematol.2024.286560.
Maillie, Luke. Nasta, Sunita D. Svoboda, Jakub. Barta, Stefan K. Chong, Elise A. Garfall, Alfred L. Gill, Saar I. Porter, David L. Schuster, Stephen J. Catania, Christopher. Frey, Noelle V. Landsburg, Daniel J.: Prolonged Neurologic Symptoms Following Immune Effector Cell-Associated Neurotoxicity Syndrome in Patients With Large B-cell Lymphoma Treated With Chimeric Antigen Receptor-Modified T Cell Therapy. Transplant Cell Ther. 31(4): 228-235, Apr 2025 Notes: doi: 10.1016/j.jtct.2025.01.884.