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Paul J.L. Zhang

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Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
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Chief Physician, China Consultation Service, AP Division, Department of Pathology and laboratory Medicine, Hospital of the University of Pennsylvania
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Consultant, Pennsylvania Hospital
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Director, Bone and Soft Tissue Pathology Subspecialty Service, , AP Division, Department of Pathology and laboratory Medicine, Hospital of the University of Pennsylvania
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Director, Breast Marker Service, AP Division, Department of Pathology and laboratory Medicine, Hospital of the University of Pennsylvania
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Department: Pathology and Laboratory Medicine
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46 Contact information
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Department of Pathology and Lab Medicine
26 Division of Anatomic Pathology
32 University of Pennsylvania Medical Center
46 3400 Spruce Street – Six Founders
Philadelphia, PA 19104
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40 Lab: 215-662-6503
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13 Education:
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41 Guangzhou Medical College, Canton, China, 1983.
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Description of Research Expertise

90 Various tumor markers in diagnostic and prognositc application. In-situ molecular morphometry in tumor diagnosis and prognosis.
116 Hypoxia in sarcoma. Translational research in sarcoma. Growth factors receptors in breast cancer. Mechanism of lymphangionesis and lymphatic invasion in cancer. The significance and determination of host immunoresponse on surgical specimen in cancer patients' prognosis.
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Description of Clinical Expertise

102 Diagnostic pathology in soft tissue tumor, sarcoma and cancers of breast, GYN tract, pulmonary tract, ENT. Diagnostic immmunohistochemical and in-situ hybridization. Evaluation of tumor markers for personalized treatment in surgical specimen.
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Selected Publications

11e Ase G, Parash TL, Zhang PJ.: WT1 is expressed in serous, but not in endometrioid, clear cell or mucinous carcinomas of the peritoneum, fallopian tube, ovaries and endometrium. Int J Gyn Pathol 23: 110-118, 2004.

12c Nasuti, JF, Zhang PJ, Feldman M, MD, PhD, Pasha TL, Khurana JS, Gorman J, Gorman R, Narula J, and Narula N : Fibrillin and Other Matrix Proteins in Mitral Valve Prolapse Syndrome. Annals of Thoracic Surgery 77: 532-535, 2004.

122 Fogt F, Pascha TL, Zhang PJ, Gausas RE, Rahemtulla A, Zimmerman RL: Proliferation of D2-40-expressing intestinal lymphatic vessels in the lamina propria in inflammatory bowel disease. Int J Mol Med 13: 221-214, 2004.

11c Scobie JV, Acs G, Bandera CA, Blank SV, Wheeler JE, Pasha TL and Zhang PJ. : C-kit Immunoreactivity in Endometrial Adenocarcinomas and Its Clinicopathologic Significance. Int J Gyn Pathol 22(2): 149-155, 2003.

139 PJ Zhang, EM Genega, JE Tomaszewski, TL Pasha, VA LiVolsi. : The Role of Calretinin, Inhibin, Melan-A, BCL-2 and c-kit in differentiating Adrenal Cortical and Medullary Tumors, An Immunohistochemical Study. Mod Pathol 16(6): 591-597, 2003.

11a Zhang PJ, Goldblum JR, Pawel BR, Fisher C, Pasha TL, Barr FG. : Immunophenotype of Desmoplastic Small Round Cell Tumors as Detected in Cases with EWS-WT1 Gene Fusion Product. Mod Pathol 16(3): 229-235, 2003.

1a4 Geza. Acs, Lynn Wang, Puthiyaveettil N. Raghunath, Marilyn A. Salscheider and Paul J. Zhang. : The Role of Different Immunostaining Patterns In Herceptest Interpretation and Their Correlation with Gene Amplification as Determined by Fluorescence in Situ Hybridization. Applied Immunohistolochemistry & Molecular Morphology 13(3): 222-229, 2003.

101 Xu X, Tahan, SR and Zhang PJ. : Expression of Neurotrophin receptor Trk-C in nevi and melanomas, an immunohistochemical study. Journal of Cutaneous Pathology 30(5): 318-322, 2003.

188 Acs G, Zhang PJ, McGrath CM, Acs P, McBroom J, Mohyeldin A Liu S, Lu Huasheng and Verma A. : Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and tis potential role in cervical carcinogenesis and tumor progression. Am J Pathol 162(6): 1790-1806, 2003.

cd Zhang PJ, Liang HH, Pasha TL, Weber R, LiVolsi VA. : Various Growth Factors, Growth Factor Recptors in Juvenile Nasopharyngeal Angiofibroma; A Comparative 2f Immunhistochemical Study with Nasal Polyps. 47 Arch Pathol Lab Med. 127(11): 1480-1484, 2003.

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26 Last updated: 07/22/2025
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