Jonathan M. Spergel, MD, PhD

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Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
3550 Market Street, Rm 3050
Children’s Hospital of Philadelphia
Philadelphia, PA 19104
Office: 215-590-6992
Fax: 2155904529
Education:
A.B. (Chemistry)
Princeton University, 1985.
Ph.D. (Biomedical Sciences)
Mt. Sinai School of Medicine, 1992.
M.D.
Mt. Sinai School of Medicine, 1992.
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Description of Research Expertise

eosinophilic esophagitis, food allergy, gastrointestinal food allergy and atopic dermatitis

Description of Clinical Expertise

atopic dermatitis, food allergy, asthma, allergic rhinitis, general allergy and immunology

Selected Publications

Mansbach Jonathan M, Hasegawa Kohei, Geller Ruth J, Espinola Janice A, Sullivan Ashley F, Camargo Carlos A: Bronchiolitis severity is related to recurrent wheezing by age 3 years in a prospective, multicenter cohort. Pediatric research Oct 2019.

Whelan Kelly A, Godwin Bridget C, Wilkins Benjamin, Elci Okan U, Benitez Alain, DeMarshall Maureen, Sharma Medha, Gross Jonathan, Klein-Szanto Andres J, Liacouras Chris A, Dellon Evan S, Spergel Jonathan M, Falk Gary W, Muir Amanda B, Nakagawa Hiroshi: Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Sep 2019.

Muir Amanda B, Jensen Elizabeth T, Wechsler Joshua B, Menard-Katcher Paul, Falk Gary W, Aceves Seema S, Furuta Glenn T, Dellon Evan S, Rothenberg Mark E, Spergel Jonathan M: Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. The journal of allergy and clinical immunology. In practice 7(7): 2434-2436, Sep - Oct 2019.

Klinnert Mary D, Atkins Dan, Pan Zhaoxing, Franciosi James P, Aceves Seema S, Spergel Jonathan M, Furuta Glenn T: Symptom Burden and Quality of Life Over Time in Pediatric Eosinophilic Esophagitis. Journal of pediatric gastroenterology and nutrition Aug 2019.

Cafone Joseph, Capucilli Peter, Hill David A, Spergel Jonathan M: Eosinophilic esophagitis during sublingual and oral allergen immunotherapy. Current opinion in allergy and clinical immunology 19(4): 350-357, Aug 2019.

Ruffner Melanie A, Song Li, Maurer Kelly, Shi Lihua, Carroll Margaret C, Wang Joshua X, Muir Amanda B, Spergel Jonathan M, Sullivan Kathleen E: Toll-like receptor 2 stimulation augments esophageal barrier integrity. Allergy Jul 2019.

Schoepfer Alain M, Hirano Ikuo, Coslovsky Michael, Roumet Marie C, Zwahlen Marcel, Kuehni Claudia E, Hafner David, Alexander Jeffrey A, Dellon Evan S, Gonsalves Nirmala, Leung John, Bussmann Christian, Collins Margaret H, Newbury Robert O, Smyrk Thomas C, Woosley John T, Yang Guang-Yu, Romero Yvonne, Katzka David A, Furuta Glenn T, Gupta Sandeep K, Aceves Seema S, Chehade Mirna, Spergel Jonathan M, Falk Gary W, Meltzer Brian A, Comer Gail M, Straumann Alex, Safroneeva Ekaterina: Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 17(8): 1477-1488.e10, Jul 2019.

Kasagi Yuta, Dods Kara, Wang Joshua X, Chandramouleeswaran Prasanna M, Benitez Alain J, Gambanga Fiona, Kluger Jonathan, Ashorobi Tokunbo, Gross Jonathan, Tobias John W, Klein-Szanto Andres J, Spergel Jonathan M, Cianferoni Antonella, Falk Gary W, Whelan Kelly A, Nakagawa Hiroshi, Muir Amanda B: Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α. The Journal of allergy and clinical immunology 144(1): 171-182, Jul 2019.

Kennedy Katie, Muir Amanda B, Grossman Andrew, Brown-Whitehorn Terri, Cianferoni Antonella, Spergel Jonathan M, Furuta Glenn T, Wilkins Benjamin J, Shuker Michele, Ruffner Melanie A: Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience. The journal of allergy and clinical immunology. In practice 7(6): 2059-2061, Jul - Aug 2019.

Lewis Megan O, Brown-Whitehorn Terri F, Cianferoni Antonella, Rooney Courtney, Spergel Jonathan M: Peanut-allergic patient experiences after epicutaneous immunotherapy: peanut consumption and impact on QoL. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 123(1): 101-103, Jul 2019.

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Last updated: 11/14/2019
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