Jonathan M. Spergel, MD, PhD

Professor of Pediatrics at the Children's Hospital of Philadelphia
Director, Food Allergy Center/ Center for Pedidatric Eosinophilic Disorders,, The Children’s Hospital of Philadelphia
Chief, Allergy Section, The Children's Hospital of Philadelphia
Division of Allergy and Immunology
SWATT CHOPlink, The Children's Hospital of Philadeelphia
memeber, Institute for Translational Medicine and Therapeutics
member, Institute for Immunology
Stuart E. Starr Endowed Chair in Pediatrics, The Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
3550 Market Street, Rm 3050
Children’s Hospital of Philadelphia
Philadelphia, PA 19104
Children’s Hospital of Philadelphia
Philadelphia, PA 19104
Office: 215-590-6992
Fax: 2155904529
Fax: 2155904529
Email:
SPERGEL@chop.edu
SPERGEL@chop.edu
Education:
A.B. (Chemistry)
Princeton University, 1985.
M.D.
Mt. Sinai School of Medicine, 1992.
Ph.D. (Biomedical Sciences)
Mt. Sinai School of Medicine, 1992.
Permanent linkA.B. (Chemistry)
Princeton University, 1985.
M.D.
Mt. Sinai School of Medicine, 1992.
Ph.D. (Biomedical Sciences)
Mt. Sinai School of Medicine, 1992.
Description of Research Expertise
eosinophilic esophagitis, food allergy, gastrointestinal food allergy and atopic dermatitisDescription of Clinical Expertise
atopic dermatitis, food allergy, asthma, allergic rhinitis, general allergy and immunologySelected Publications
Sehgal S, Gupta RS, Wlodarski M, Bilaver LA, Wehbe FH, Spergel JM, Wang J, Ciaccio CE, Makhija M, Starren JB.: Development of Food Allergy data dictionary: towards a Food Allergy Data Commons. J Allergy Clin Immunol Pract Mar 2022.Fiocchi A, Bognanni A, Brożek J, Ebisawa M, Schünemann H; WAO DRACMA guideline group.: World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - I - Plan and definitions. World Allergy Organ J 15: 100609, Feb 2022.
Hiremath G, Sun L, Correa H, Acra S, Collins MH, Bonis P, Arva NC, Capocelli KE, Falk GW, King E, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Martin LJ, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES.: Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. Am J Gastroenterol 117: 272-279, Feb 2022.
Zhang S, Shoda T, Aceves SS, Arva NC, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Spergel AKR, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group.: Mast cell-pain connection in eosinophilic esophagitis. Allergy Feb 2022.
Dellon ES, Gonsalves N, Abonia JP, Alexander JA, Arva NC, Atkins D, Attwood SE, Auth MK, Bailey DD, Biederman L, Blanchard C, Bonis PA, Bose P, Bredenoord AJ, Chang JW, Chehade M, Collins MH, Di Lorenzo C, Dias JA, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox AT, Genta RM, Greuter T, Gupta SK, Hirano I, Hiremath GS, Horsley-Silva JL, Ishihara S, Ishimura N, Jensen ET, Gutiérrez-Junquera C, Katzka DA, Khoury P, Kinoshita Y, Kliewer KL, Koletzko S, Leung J, Liacouras CA, Lucendo AJ, Martin LJ, McGowan EC, Menard-Katcher C, Metz DC, Miller TL, Moawad FJ, Muir AB, Mukkada VA, Murch S, Nhu QM, Nomura I, Nurko S, Ohtsuka Y, Oliva S, Orel R, Papadopoulou A, Patel DA, Pesek RD, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Ruffner MA, Safroneeva E, Schreiner P, Schoepfer A, Schroeder SR, Shah N, Souza RF, Spechler SJ, Spergel JM, Straumann A, Talley NJ, Thapar N, Vandenplas Y, Venkatesh RD, Vieira MC, von Arnim U, Walker MM, Wechsler JB, Wershil BK, Wright BL, Yamada Y, Yang GY, Zevit N, Rothenberg ME, Furuta GT, Aceves SS.: International consensus recommendations for eosinophilic gastrointestinal disease nomenclature. Clin Gastroenterol Hepatol Feb 2022.
Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, Shimonosono M, Shimonosono R, Maekawa H, Dolinsky L, Wilkins B, Klein J, Wei J, Nunes K, Lynch K, Spergel JM, Hamilton KE, Ruffner MA, Karakasheva TA, Whelan KA, Nakagawa H, Muir AB.: CD73(+) Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cell Mol Gastroenterol Hepatol Jan 2022.
Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Klion A, Menard-Katcher C, Leung J, Mukkada V, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Denson LA, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Diseases Researchers (CEGIR).: Evaluating Eosinophilic Colitis as a Unique Disease using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology Jan 2022.
Spergel BL, Ruffner MA, Godwin BC, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TF, Chaiboonma K, Aceves SA, Muir AM, Spergel JM.: Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use. Ann Allergy Asthma Immunol Jan 2022.
Rothenberg ME, Hottinger SKB, Gonsalves N, Furuta GT, Collins MH, Talley NJ, Peterson K, Menard-Katcher C, Smith M, Hirano I, Genta RM, Chehade M, Gupta SK, Spergel JM, Aceves SS, Dellon ES.: Impressions and aspirations from the FDA GREAT VI Workshop on Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis and Perspectives for Progress in the Field. J Allergy Clin Immunol 2022.
Nguyen K, Greenthal E, Sorscher S, Lurie P, Spergel JM, Kennedy K.: Adverse events and labeling issues related to suspected sesame allergy reported in an online survey. Ann Allergy Asthma Immunol 2022.