Jonathan M. Spergel, MD, PhD
Professor of Pediatrics (Allergy/Immunology ) at the Children's Hospital of Philadelphia
Director, Food Allergy Center/ Center for Pedidatric Eosinophilic Disorders,, The Children’s Hospital of Philadelphia
Chief, Allergy Section, The Children's Hospital of Philadelphia
Division of Allergy and Immunology
memeber, Institute for Translational Medicine and Therapeutics
member, Institute for Immunology
Stuart E. Starr Endowed Chair in Pediatrics, The Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
3550 Market Street, Rm 3050
Children’s Hospital of Philadelphia
Philadelphia, PA 19104
Children’s Hospital of Philadelphia
Philadelphia, PA 19104
Office: 215-590-6992
Fax: 2155904529
Fax: 2155904529
Email:
SPERGEL@chop.edu
SPERGEL@chop.edu
Education:
A.B. (Chemistry)
Princeton University, 1985.
Ph.D. (Biomedical Sciences)
Mt. Sinai School of Medicine, 1992.
M.D.
Mt. Sinai School of Medicine, 1992.
Permanent linkA.B. (Chemistry)
Princeton University, 1985.
Ph.D. (Biomedical Sciences)
Mt. Sinai School of Medicine, 1992.
M.D.
Mt. Sinai School of Medicine, 1992.
Description of Research Expertise
eosinophilic esophagitis, food allergy, gastrointestinal food allergy and atopic dermatitisDescription of Clinical Expertise
atopic dermatitis, food allergy, asthma, allergic rhinitis, general allergy and immunologySelected Publications
Day K, Bredenoord AJ, Skypala I, Spergel J, Bickford K, Noble A, Nunn AM.: Addressing educational gaps through multidisciplinary team education in eosinophilic oesophagitis management. J CME 12: 2230033, Jul 2023.Conrey PE, Denu L, O'Boyle KC, Rozich I, Green J, Maslanka J, Lubin JB, Duranova T, Haltzman BL, Gianchetti L, Oldridge DA, De Luna N, Vella LA, Allman D, Spergel JM, Tanes C, Bittinger K, Henrickson SE, Silverman MA.: IgA deficiency destabilizes homeostasis toward intestinal microbes and increases systemic immune dysregulation. Sci Immunol 8: eade2335, May 2023.
Simpson EL, De Benedetto A, Boguniewicz M, Ong PY, Lussier S, Villarreal M, Schneider LC, Paller AS, Guttman-Yassky E, Hanifin JM, Spergel JM, Barnes KC, David G, Austin B, Leung DYM, Beck LA.: Phenotypic and Endotypic Determinants of Atopic Dermatitis Severity From the Atopic Dermatitis Research Network (ADRN) Registry. J Allergy Clin Immunol Pract May 2023.
Furuta GT, Fillon SA, Williamson KM, Robertson CE, Stevens MJ, Aceves SS, Arva NC, Chehade M, Collins MH, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Martin LJ, Menard-Katcher P, Mukkada VA, Peterson K, Spergel JM, Wechsler JB, Yang GY, Rothenberg ME, Harris JK.: Mucosal Microbiota Associated With Eosinophilic Esophagitis and Eosinophilic Gastritis. J Pediatr Gastroenterol Nutr 76: 347-354, Mar 2023.
Hiremath G, Sun L, Collins MH, Bonis PA, Arva NC, Capocelli KE, Chehade M, Davis CM, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Khoury P, Mukkada VA, Martin LJ, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES.: Esophageal Epithelium and Lamina Propria Are Unevenly Involved in Eosinophilic Esophagitis. Clin Gastroenterol Hepatol Mar 2023.
Dupuis R, Feuerstein-Simon R, Brown-Whitehorn TF, Spergel JM, Volpp KG, Marti XL, Troxel AB, Meisel ZF, Mollen CJ, Kenney EL, Block J, Gortmaker SL, Cannuscio CC.: Food Allergy Management for Adolescents Using Behavioral Incentives: A Randomized Trial. Pediatrics 151: e2022058876, Feb 2023.
Gautam Y, Caldwell J, Kottyan L, Chehade M, Dellon ES, Rothenberg ME, Mersha TB; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) investigators.: Genome-wide admixture and association analysis identifies African ancestry-specific risk loci of eosinophilic esophagitis in African Americans. J Allergy Clin Immunol 2023.
Gupta RS, Sehgal S, Wlodarski M, Bilaver LA, Wehbe FH, Spergel JM, Wang J, Ciaccio CE, Nimmagadda SR, Assa'ad A, Mahdavinia M, Wasserman RL, Brown E, Sicherer SH, Bird JA, Roberts B, Sharma HP, Mendez K, Holding EG, Mitchell L, Corbett M, Makhija M, Starren JB.: Accelerating Food Allergy Research: Need for a Data Commons. J Allergy Clin Immunol Pract 2023.
Nguyen K, Lewis MO, Hanna E, Alfaro MKC, Corrigan K, Buonanno J, Datta R, Brown-Whitehorn T, Spergel JM, Cianferoni A.: Safety of Multifood Oral Immunotherapy in Children Aged 1 to 18 Years at an Academic Pediatric Clinic. J Allergy Clin Immunol Pract 2023.
Groetch M, Mudd K, Woch M, Schaible A, Gray BE, Babineau DC, Bird JA, Jones S, Kim EH, Lanser BJ, Poyser J, Rogers N, Shreffler W, Sicherer S, Spergel AKR, Spergel J, Vickery BP, Chinthrajah RS, Wood R.: Retail Food Equivalents for Post-Oral Immunotherapy Dosing in the Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen Oral Immunotherapy in Food-Allergic Children and Adults (OUtMATCH) Clinical Trial. J Allergy Clin Immunol Pract 2023.