John A. Wolf, Ph.D.

faculty photo
Research Assistant Professor of Neurosurgery
Department: Neurosurgery
Graduate Group Affiliations

Contact information
Rm.172A Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Office: 215-746-4680
Lab: 215-898-5102
B.A. (Biology)
University of Pennsylvania, 1994.
Ph.D. (Neuroscience)
University of Pennsylvania, 2006.
M.S.Ed (School and Mental Health Counseling)
University of Pennsylvania, 2011.
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Description of Research Expertise

My laboratory focuses on the effects of traumatic brain injury on the limbic system, including the hippocampus, PFC, and amygdala. We are particularly interested in the changes in coding in these structures, as well as the interactions between them, in both cognition and emotional processing. We are developing new targets of neuromodulation for these regions and their connections as well.

Selected Publications

Koch, P. F., Cottone, C., Adam, C. D., Ulyanova, A. V., Russo, R. J., Weber, M. T., Arena, J. D., Johnson, V. E., Wolf, J. A.: Traumatic Brain Injury Preserves Firing Rates But Disrupts Laminar Oscillatory Coupling and Neuronal Entrainment in Hippocampal CA1. eNeuro 7(5), 2020.

Grovola, M. R., Paleologos, N., Wofford, K. L., Harris, J. P., Browne, K. D., Johnson, V., Duda, J. E., Wolf, J. A., Cullen, D. K.: Mossy cell hypertrophy and synaptic changes in the hilus following mild diffuse traumatic brain injury in pigs. J Neuroinflammation 17(1): 44, 2020.

Harris, J. P., Burrell, J. C., Struzyna, L. A., Chen, H. I., Serruya, M. D., Wolf, J. A., Duda, J. E., Cullen, D. K.: Emerging regenerative medicine and tissue engineering strategies for Parkinson''s disease. NPJ Parkinsons Dis 6: 4, 2020.

Qian, X., Su, Y., Adam, C. D., Deutschmann, A. U., Pather, S. R., Goldberg, E. M., Su, K., Li, S., Lu, L., Jacob, F., Nguyen, P. T. T., Huh, S., Hoke, A., Swinford-Jackson, S. E., Wen, Z., Gu, X., Pierce, R. C., Wu, H., Briand, L. A., Chen, H. I., Wolf, J. A., Song, H., Ming, G. L.: Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation. Cell Stem Cell 26(5): 766-781.e9, 2020.

Burrell, J. C., Browne, K. D., Dutton, J. L., Laimo, F. A., Das, S., Brown, D. P., Roberts, S., Petrov, D., Ali, Z., Ledebur, H. C., Rosen, J. M., Kaplan, H. M., Wolf, J. A., Smith, D. H., Chen, H. I., Cullen, D. K.: A Porcine Model of Peripheral Nerve Injury Enabling Ultra-Long Regenerative Distances: Surgical Approach, Recovery Kinetics, and Clinical Relevance. Neurosurgery 2020.

Chen HI, Wolf JA, Blue R, Song MM, Moreno JD, Ming GL, Song H.: Transplantation of Human Brain Organoids: Revisiting the Science and Ethics of Brain Chimeras. Cell Stem Cell 25(4): 462-472, Oct 2019.

Weber, M. T., Arena, J. D., Xiao, R., Wolf, J. A., Johnson, V. E.: CLARITY reveals a more protracted temporal course of axon swelling and disconnection than previously described following traumatic brain injury. Brain Pathol 29(3): 437-450, 2019.

Adewole, D. O., Serruya, M. D., Wolf, J. A., Cullen, D. K.: Bioactive Neuroelectronic Interfaces. Front Neurosci 13: 269, 2019.

Chen, H. I., Jgamadze, D., Lim, J., Mensah-Brown, K., Wolf, J. A., Mills, J. A., Smith, D. H.: Functional Cortical Axon Tracts Generated from Human Stem Cell-Derived Neurons. Tissue Eng Part A 25(9-10): 736-745, 2019.

Ulyanova, A. V., Cottone, C., Adam, C. D., Gagnon, K. G., Cullen, D. K., Holtzman, T., Jamieson, B. G., Koch, P. F., Chen, H. I., Johnson, V. E., Wolf, J. A.: Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals. Front Neurosci 13: 397, 2019.

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Last updated: 12/14/2020
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