James M. Metz, M.D.

faculty photo
Henry K. Pancoast Professor of Radiation Oncology
Active Physician, Penn Presbyterian Medical Center
Attending Physician, Hospital of the University of Pennsylvania
Associate Director for Clinical Service & Programs, Abramson Comprehensive Cancer Center, University of Pennsylvania
Vice Chair, Clinical Division, Department of Radiation Oncology, Hospital of the University of Pennsylvania
Executive Director, OncoLink, Abramson Comprehensive Cancer Center, University of Pennsylvania
Vice Chair, Department of Radiation Oncology, Hospital of the University of Pennsylvania
Chair, Radiation Oncology, University of Pennsylvania
Department: Radiation Oncology

Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
2 West
Philadelphia, PA 19104
Office: 215-349-5570
Fax: 215-349-5923
BS (Biology)
Juniata College , 1989.
MS (Clinical Immunology/Microbiology)
Hahnemann University , 1991.
MD (Medicine)
UMDNJ-Robert Wood Johnson Med School, 1995.
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Description of Clinical Expertise

Dr. Metz serves as Chair of Radiation Oncology at the Perelman School of Medicine and holds the Henry K. Pancoast Endowed Professorship. He is Associate Director for Clinical Services and Programs at the Abramson Comprehensive Cancer Center of the University of Pennsylvania. Dr. Metz led the development of the Roberts Proton Therapy Center, the largest proton center in the world completely integrated with conventional cancer services. Dr. Metz has become an international leader in the application of proton therapy for the treatment of a variety of malignancies. He continues to work to integrate proton therapy as a new treatment paradigm for cancer and is leading the expansion of proton therapy.

Dr. Metz specializes in the use of radiation for the treatment of gastrointestinal malignancies. His research interests include the treatment of GI malignancies in the multidisciplinary setting, as well as the utilization of complementary and alternative medications by cancer patients, and use of the Internet to provide cancer related information. A major area of interest has been the development of proton therapy at Penn and internationally.

Dr. Metz also serves as Executive Director of OncoLink (www.oncolink.upenn.edu), the award winning Internet resource from the Abramson Comprehensive Cancer Center of the University of Pennsylvania that was founded in 1994. As Executive Director, Dr. Metz leads OncoLink’s mission to help cancer patients, families, health care professionals, and the general public find accurate cancer-related information online. The website has led the way in online education for cancer patients and healthcare providers, receiving numerous awards and recognition from most major authorities as one of the best cancer information websites. Currently OncoLink is developing interactive content and personalized information for individuals while collecting important information to move the field forward, particularly in the area of cancer survivorship. Its reach is international in scope with over 285,000 unique visitors served per month.

Selected Publications

Amaniera I, Bach C, Vachani C, Hampshire M, Arnold-Korzeniowski K, Healy M, Rodriguez A, Misher C, Kendrick L, Metz JM, Hill-Kayser CE.: Psychosocial impact of the COVID-19 pandemic on cancer patients, survivors and caregivers. 2021 Apr 19:1-7. PMID: J Psychosoc Oncol. 19: 1-7, April 2021 Notes: doi: 10.1080/07347332.2021.1913780. Online ahead of print.

Zou W, Diffenderfer ES, Ota K, Boisseau P, Kim MM, Cai Y, Avery SM, Carlson DJ, Wiersma RD, Lin A, Koumenis C, Cengal K, Metz JM, Dong L, Teo BK.: Characterization of a high-resolution 2D transmission ion chamber for independent validation of proton pencil beam scanning of conventional and FLASH dose delivery. Med Phys. April 2021 Notes: doi: 10.1002/mp.14882. Online ahead of print.

King-Dowling S, Psihogios AM, Hill-Kayser C, Szalda D, O'Hagan B, Darabos K, Daniel LC, Barakat LP, Fleisher L, Maurer LA, Velázquez-Martin B, Jacobs LA, Hobbie W, Ginsberg JP, Vachani CC, Metz JM, Schwartz LA: Acceptability and feasibility of survivorship care plans and an accompanying mobile health intervention for adolescent and young adult survivors of childhood cancer. 2021 Mar;68(3): Epub 2021 Jan 8.PMID: Pediatr Blood Cancer. 68: e28884, March 2021 Notes: doi: 10.1002/pbc.28884.

Zou W, Diffenderfer ES, Cengel KA, Kim MM, Avery S, Konzer J, Cai Y, Boisseu P, Ota K, Yin L, Wiersma R, Carlson DJ, Fan Y, Busch TM, Koumenis C, Lin A, Metz JM, Teo BK, Dong L.: Current delivery limitations of proton PBS for FLASH. Radiotherapy and Oncology 155: 212-218, February 2021 Notes: doi: 10.1016/j.radonc.2020.11.002.

Dreyfuss AD, Barsky AR, Wileyto EP, Eads JR, Kucharczuk JC, Williams NN, Karasic TB, Metz JM, Ben-Josef E, Plastaras JP, Wojcieszynski AP: The efficacy and safety of definitive concurrent chemoradiotherapy for non-operable esophageal cancer. Cancer Medicine 10(4): 1275-1288, February 2021 Notes: doi: 10.1002/cam4.3724.

Yoon SW, Taunk NK, Freedman GM, Hubley E, O'Reilly S, Teo BKK, Anamalayil S, Dong L, Kennedy C, Zou W, Metz JM, Li T.: Per-fraction positional and dosimetric performance of prone breast tangential radiotherapy on Halcyon™ linear accelerator assessed with daily rapid kilo-voltage cone beam computed tomography: a single-institution pilot study. Radiation Oncology 15: 258, November 2020 Notes: doi: 10.1186/s13014-020-01700-

Barsky AR, Lin H, Mendes A, Dreyfuss A, Wright C, Anstadt EJ, Berman AT, Levin WP, Cengel KA, Anderson N, Dong L, Metz JM, Li T, Feigenberg S.Cureus.: Initial Clinical Experience Treating Patients With Lung Cancer on a 6MV-Flattening-Filter-Free O-Ring Linear Accelerator. Cureus Journal of Medical Science September 2020 Notes: doi: 10.7759/cureus.10325.

Barsky AR, Kim MM, Maxwell R, Mendes A, Wright CM, Anstadt EJ, McNulty S, Dong L, Metz JM, Feigenberg SJ, Li T, Cengel KA.: Initial clinical experience treating patients with palliative radiotherapy for malignant pleural mesothelioma on the HalcyonTM linear accelerator. Ann Palliat Med. Page: 20-385, August 2020 Notes: doi: 10.21037/apm-20-385.

Yoon SW, Lin H, Alonso-Basanta M, Anderson N, Apinorasethkul O, Cooper K, Dong L, Kempsey B, Marcel J, Metz J, Scheuermann R, Li T.: Initial Evaluation of a Novel Cone-Beam CT-Based Semi-Automated Online Adaptive Radiotherapy System for Head and Neck Cancer Treatment - A Timing and Automation Quality Study. Cureus. 12: e9660, August 2020 Notes: doi: 10.7759/cureus.9660.

Mante A, Hawrot K, Bvochora-Nsingo M, Chiyapo S, Balang D, Barg F, Baffic C, Monare B, Vapiwala N, Ralefala T, Metz J, Swisher-McClure S, Grover S.: Radiation Oncology Rotation in Botswana: Resident Experience and Career Interests. Int J Radiat Oncol Biol Phys. 107: 850-852, July 2020 Notes: doi: 10.1016/j.ijrobp.2020.03.017.

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Last updated: 05/01/2024
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