Brian J. Czerniecki, M.D., Ph.D.
Division of Surgical Oncology
Hospital of the University of Pennsylvania
3400 Civic Center Drive, 3 Perelman Center
Philadelphia, PA 19104
University of Maine, 1982.
Rutgers University/UMDNJ/RWJMS, 1988.
University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School, 1988.
Selected PublicationsChoe, R, Konecky SD, Corlu A, Lee K, Durduran T, Busch DR, Pathak S, Czerniecki BJ, Tchou J, Fraker DL, DeMichele A, Chance B, Arridge SR, Schweiger M, Culver JP, Schnall MD, Putt ME, Rosen MA,Yodh AG.: Differentiation of benign and malignant breast tumors by in vivo three dimensional parallel-plate diffuse optical tomography. Journal of Biomedical Optics. 14, 2009.
Bahl S, Roses R, Sharma, A, Koldovsky U, Xu S, Weinstein S, Nisenbaum H, Fox K, Pasha T, Zhang P, Araujo L, Carver J, Czerniecki BJ.: Asymptomatic changes in cardiac function can occur in DCIS patients following treatment with HER-2/neu pulsed dendritic cell vaccines. Am Journal Surgery. 2009.
Roses RE, Paulson C, Sharma A, Schueller JE, Nisenbaum H, Weinstein S, Fox KR, Zhang PJ, Czerniecki BJ.: HER-2/neu over-expression as a predictor for the transition from in situ to invasive breast cancer. Cancer Epidemiology, Biomarkers and Prevention. 18: 1386-1389, 2009.
Koski GK, Roses R, Xu S, Cohen PA, Czerniecki BJ.: Re-engineering dendritic cell-based anti-cancer vaccines. Immunologic Reviews. 222: 256-276, 2008.
Sharma A, Czerniecki BJ.: Utilizing Genetic Phenotypes and Cancer Stem Cells as Novel Targets for Breast Cancer Vaccine Development. Current Medical Literature Breast Cancer. 20(3): 61-67, 2008.
Roses RE, Xu S, Xu M, Koldovsky U, Koski G, Czerniecki BJ.: Differential production of interleukin-23 and interleukin-12 by myeloid derived dendritic cells in response to toll-like receptor agonists. J Immunol. 181: 5120-5127, 2008.
Tchou J, Greshock J, Bergey M, Sonnad SS, Sargen M, Weinstein S, Czerniecki B, Boraas M, Fraker DL, Rosato E, Fox K, Weber B, Solin LJ.: Method of primary tumor detection as a risk factor for local and distant recurrence after breast conservation treatment for early stage breast cancer. Clinical Breast Cancer. 8: 2, 2008.
Cohen PA, Koski GK, Czerniecki BJ, Bunting K, Fu XY, Wang Z, Zhang WJ, Carter C, Awad M, Distel CA, Hassen N, Paustian C, Johnson T, Tisdale JF, Shu S.: STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34 positive cells into tumor-competent dendritic cells. Blood. 112: 1832-1843, 2008.
Roses R, Xu M, Koski GK, Czerniecki BJ.: Radiation therapy and toll-like receptor signaling: implications for the treatment of cancer. Oncogene. 27: 200-207, 2008.
Kuerer HM, Albarracin CT, Yang WT, Cardiff RD, Brewster AM, Symmans WF, Hylton NM, Middleton LP, Krishnamurthy S, Perkins GH, Barbiera G, Edgerton ME, Czerniecki BJ, Arun BK, Hortobagyi GN.: Ductal carcinoma in situ: state of the science and roadmap to advance the field. J Clinical Oncology. 27: 1-10, 2008.