Robert B. Wilson, MD, PhD

faculty photo
Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
Children’s Hospital of Philadelphia
Room 6024, Colket Translational Research Building
3501 Civic Center Blvd.
Philadelphia, PA 19104
Office: 267-425-2201
Education:
A.B. (Music)
Brown University, 1982.
Sc.B. (Biochemistry)
Brown University, 1982.
M.D.
University of Pennsylvania, 1989.
Ph.D. (Genetics)
University of Pennsylvania, 1989.
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Selected Publications

Cotticelli, M. G., Xia, S., Lee, T., Wilson, R. B.: An iPS-derived cardiomyocyte model of Friedreich ataxia. Manuscript in preparation 2019.

Cotticelli, M. G., Xia, S., Lin, D., Lee, T., Lin, D., Huryn, D., Smith, A., Wilson, R. B.: Oleic Acid and Oleic Acid Derivatives as a Treatment for Friedreich Ataxia. Manuscript in Preparation 2019.

Cotticelli, M. G., Xia, S., Kaur, A., Lin, D., Wang, Y., Ruff, E., Tobias, J. W., Wilson, R. B. : Identification of p38 MAPK as a novel therapeutic target for Friedreich’s ataxia. Scientific Reports 8(1): 5007, 2018.

Cotticelli, M. G., Xia, S., Lin, D., Lee, T., Lin, D., Terrab, L., Wipf, P., Huryn, D., Wilson, R. B.: Ferroptosis as a novel therapeutic target for Friedreich’s ataxia. Journal of Pharmacology and Experimental Therapeutics In press, 2018.

Seyer L., Greeley N., Foerster D., Strawser C., Gelbard S., Dong Y., Schadt K., Cotticelli M.G., Brocht A., Farmer J., Wilson R.B., Lynch D.R.: Open label pilot study of interferon gamma-1b in Friedreich ataxia. Acta Neurologica Scandinavica 132: 7-15, 2015.

Cotticelli, M. G., Acquaviva, F., Xia S., Kaur, A., Wang, Y., and Wilson, R. B.: Phenotypic screening for Friedreich ataxia using random shRNA selection. Journal of Biomolecular Screening 20: 1084-1090, 2015.

Lazaropolous, M., Dong, Y., Clark, E., Greeley, N. R., Seyer, L. A., Brigatti, K. W., Christie, C., Perlman, S. L., Wilmot, G. R., Gomez, C. M., Mathews, K. D., Yoon, G., Zesiewicz, T., Hoyle, C., Subramony, S. H., Brocht, A. F., Farmer, J. M., Wilson, R. B., Deutsch, E. C. and Lynch, D. R. : Frataxin levels in peripheral tissue in Friedreich ataxia. Annals of Clinical and Translational Neurology 2: 831-842, 2015.

Wang, Y., Speier, J., Engram-Pearl, J., Wilson, R. B.: Introduction of Mismatches in a Random shRNA-encoding Library Improves Potency for Phenotypic Selection. PLoS ONE 9: e87390, 2014.

Cotticelli, M. G., Crabbe, A. M., Wilson, R. B., and Shchepinov, M. S.: Insights into the role of oxidative stress in the pathology of Friedreich Ataxia using peroxidation resistant polyunsaturated fatty acids. Redox Biology 1: 398-404, 2013.

Lynch, D. R., Willi, S. M., Wilson, R. B., Cotticelli, M. G., Brigatti, K., Deutsch, E. C., Kucheruk, O., Shrader, W., Rioux, P., Miller, G., Hawi, A., Sciascia, T.: A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial. Movement Disorders 8: 1026-1033, 2012.

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Last updated: 04/16/2019
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