Ian Frank, MD

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
502 Johnson Pavilion
3610 Hamilton Walk 6073
Philadelphia, PA 19104-6073
Office: 215-662-7419
Fax: 215-349-8011
Education:
AB (Russian)
Dartmouth College, 1977.
MD (Medicine)
Dartmouth Medical School, 1980.
Permanent link
 
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Description of Research Expertise

HIV vaccinology, prevention, treatment, pathogenesis

Description of Clinical Expertise

HIV and AIDS, Lesbian, Gay, Bisexual and Transgender Health (LGBT)

Selected Publications

Li SS, Gilbert PB, Carpp LN, Pyo CW, Janes H, Fong Y, Shen X, Neidich SD, Goodman D, deCamp A, Cohen KW, Ferrari G, Hammer SM, Sobieszczyk ME, Mulligan MJ, Buchbinder SP, Keefer MC, DeJesus E, Novak RM, Frank I, McElrath MJ, Tomaras GD, Geraghty DE, Peng X: Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial. J Virol 93(21), Nov 2019.

Neidich SD, Fong Y, Li SS, Geraghty DE, Williamson BD, Young WC, Goodman D, Seaton KE, Shen X, Sawant S, Zhang L, deCamp AC, Blette BS, Shao M, Yates NL, Feely F, Pyo CW, Ferrari G, Frank I, Karuna ST, Swann EM, Mascola JR, Graham BS, Hammer SM, Sobieszczyk ME, Corey L, Janes HE, McElrath MJ, Gottardo R, Gilbert PB, Tomaras GD: Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk. J Clin Invest Page: pii: 126391, Oct 2019.

Rouphael NG, Morgan C, Li SS, Jensen R, Sanchez B, Karuna S, Swann E, Sobieszczyk ME, Frank I, Wilson GJ, Tieu HV, Maenza J, Norwood A, Kobie J, Sinangil F, Pantaleo G, Ding S, McElrath MJ, De Rosa SC, Montefiori DC, Ferrari G, Tomaras GD, Keefer MC: DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial. J Clin Invest Sep 2019.

Del Alcazar D, Wang Y, He C, Wendel BS, Del Río-Estrada PM, Lin J, Ablanedo-Terrazas Y, Malone MJ, Hernandez SM, Frank I, Naji A, Reyes-Terán G, Jiang N, Su LF: Mapping the Lineage Relationship between CXCR5 and CXCR5 CD4 T Cells in HIV-Infected Human Lymph Nodes. Cell reports 28(12): 3047-3060.e7, Sep 2019.

Ashare RL, Thompson M, Serrano K, Leone F, Metzger D, Frank I, Gross R, Hole A, Mounzer K, Collman RG, Wileyto EP, Schnoll R: Placebo-controlled randomized clinical trial testing the efficacy and safety of varenicline for smokers with HIV. Drug Alcohol Depend 200: 26-33, Jul 2019.

Schnoll RA, Thompson M, Serrano K, Leone F, Metzger D, Frank I, Gross R, Mounzer K, Tyndale RF, Weisbrot J, Meline M, Collman RG, Ashare RL: Brief Report: Rate of Nicotine Metabolism and Tobacco Use Among Persons With HIV: Implications for Treatment and Research. J Acquir Immune Defic 80(2): e36-e40, Feb 2019.

Elizaga ML, Li SS, Kochar NK, Wilson GJ, Allen MA, Tieu Hong VN, Frank I, Sobieszczyk ME, Cohen KW, Sanchez B, Latham TE, Clarke DK, Egan MA, Eldridge JH, Hannaman D, Xu R, Ota-Setlik A, McElrath MJ, Hay CM, NIAID HIV Vaccine Trials Network (HVTN) 087 Study Team: Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial. PloS One 13(9): e0202753, Sep 2018.

Murray MI, Markowitz M, Frank I, Grant RM, Mayer KH, Hudson KJ, Stancil BS, Ford SL, Patel P, Rinehart AR, Spreen WR, Margolis DA: Satisfaction and acceptability of cabotegravir long-acting injectable suspension for prevention of HIV: Patient perspectives from the ECLAIR trial. HIV Clin Trials 19(4): 129-138, Aug 2018.

Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR: Identification and characterization of HIV-specific resident memory CD8 T cells in human lymphoid tissue. Sci Immunol 3(24), Jun 2018.

Kolomeyer AM, Murphy KM, Traband A, Frank I, Kim BJ: BETA-D-GLUCAN TESTING IN PATIENTS WITH FUNGAL ENDOPHTHALMITIS. Retina 38(4): 650-659, Apr 2018.

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Last updated: 10/17/2019
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