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Michael C. Phillips, Ph.D., D.Sc.
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Adjunct Professor of Medicine (Gastroenterology, Hepatology and Nutrition)
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Stokes Investigator and Senior Member, Research Institute, The Children’s Hospital of Philadelphia
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Department: Medicine
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Contact information
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CHOP
1e 3615 Civic Center Blvd
15 Room 1102 ARC
27 4399
Philadelphia, PA 19104
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1e 3615 Civic Center Blvd
15 Room 1102 ARC
27 4399
Philadelphia, PA 19104
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Office: 215-590-0587
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32 Fax: 215-590-0583
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Email:
phillipsmi@email.chop.edu
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phillipsmi@email.chop.edu
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Education:
21 a B.Sc. 26 (Chemistry and Mathematics) c
46 Southampton University, Southampton, England , 1962.
21 a Ph.D. e ( ) c
45 Southampton University, Southampton, England, 1965.
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Permanent link21 a B.Sc. 26 (Chemistry and Mathematics) c
46 Southampton University, Southampton, England , 1962.
21 a Ph.D. e ( ) c
45 Southampton University, Southampton, England, 1965.
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11a Duong PT, Weibel GL, Lund-Katz S, Rothblat GH, Phillips MC: "Characterization and Properties of Pre Beta-HDL Particles Formed by ABCA1-mediated Cellular Lipid Efflux to ApoA-I" J Lipid Res 49: 1006-1014, 2008.
17f Vedhachalam C, Duong PT, Nickel M, Nguyen D, Dhanasekaran P, Sait H, Rothblat GH, Lund-Katz S, Phillips MC: "Mechanism of ATP-binding Cassette Transporter AI (ABCA1)-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles" J. Biol. Chem. 282: 25123-25130, 2007.
102 Vedhachalam C, Gehring AB, Davidson WS, Lund-Katz S, Rotyhblat GH, Phillips MC: "ABCA1-induced Cell Surface Binding Sites for ApoA-I" Arterioscler Thromb Vasc Biol. 27: 1603-1609, 2007.
f5 Duong PT, Collins HL, Nickel M, Lund-Katz S, Rothblat GH, Phillips MC: "Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I" 37 J Lipid Res 47: 832-843, 2006.
ec Vedhachalam C, Liu L, Nickel M, Dhanasekaran P, Anantharamaiah GM, Lund-Katz S, Rothblat GH, Phillips MC: "Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids" 3c J Biol Chem 279: 49931-49939, 2004.
ea Saito H, Dhanasekaran P, Nguyen D, Deridder E, Holvoet P, Lund-Katz S, Phillips MC: "Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids" 3c J Biol Chem 279: 20974-20981, 2004.
155 Thuahnai ST, Lund-Katz S, Dhanasekaran P, de la Llera-Moya M, Connelly MA, Williams DL, Rothblat GH, Phillips MC: "Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure" 3b J Biol Chem 13: 12448-12455, 2004.
d7 Saito H, Dhanasekaran P, Nguyen D, Holvoet P, Lund-Katz S, Phillips MC: "Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model" 3c J Biol Chem 278: 23227-23232, 2003.
eb Jonas A, Phillips MC: "Lipoprotein Structure" Biochemistry of Lipids, Lipoproteins and Membranes. D.E. Vance and J.E. Vance (eds.). Elsevier, Page: 485-506, 2008.
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Selected Publications
124 Tanaka M, Koyama M, Dhanasekaran P, Nguyen D, Nickel M, Lund-Katz S, Saito H, Phillips MC: "Influence of Tertiary Structure Domain Properties on the functionality of Apolipoprotein A-I" Biochemistry 47: 2172-2180, 2008.11a Duong PT, Weibel GL, Lund-Katz S, Rothblat GH, Phillips MC: "Characterization and Properties of Pre Beta-HDL Particles Formed by ABCA1-mediated Cellular Lipid Efflux to ApoA-I" J Lipid Res 49: 1006-1014, 2008.
17f Vedhachalam C, Duong PT, Nickel M, Nguyen D, Dhanasekaran P, Sait H, Rothblat GH, Lund-Katz S, Phillips MC: "Mechanism of ATP-binding Cassette Transporter AI (ABCA1)-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles" J. Biol. Chem. 282: 25123-25130, 2007.
102 Vedhachalam C, Gehring AB, Davidson WS, Lund-Katz S, Rotyhblat GH, Phillips MC: "ABCA1-induced Cell Surface Binding Sites for ApoA-I" Arterioscler Thromb Vasc Biol. 27: 1603-1609, 2007.
f5 Duong PT, Collins HL, Nickel M, Lund-Katz S, Rothblat GH, Phillips MC: "Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I" 37 J Lipid Res 47: 832-843, 2006.
ec Vedhachalam C, Liu L, Nickel M, Dhanasekaran P, Anantharamaiah GM, Lund-Katz S, Rothblat GH, Phillips MC: "Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids" 3c J Biol Chem 279: 49931-49939, 2004.
ea Saito H, Dhanasekaran P, Nguyen D, Deridder E, Holvoet P, Lund-Katz S, Phillips MC: "Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids" 3c J Biol Chem 279: 20974-20981, 2004.
155 Thuahnai ST, Lund-Katz S, Dhanasekaran P, de la Llera-Moya M, Connelly MA, Williams DL, Rothblat GH, Phillips MC: "Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure" 3b J Biol Chem 13: 12448-12455, 2004.
d7 Saito H, Dhanasekaran P, Nguyen D, Holvoet P, Lund-Katz S, Phillips MC: "Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model" 3c J Biol Chem 278: 23227-23232, 2003.
eb Jonas A, Phillips MC: "Lipoprotein Structure" Biochemistry of Lipids, Lipoproteins and Membranes. D.E. Vance and J.E. Vance (eds.). Elsevier, Page: 485-506, 2008.
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