John C. Kucharczuk, M.D., FACS

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Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia and the Pennsylvania Hospital
Active Surgeon, Presbyterian Medical Center, Philadelphia, PA, University of Pennsylvania
Active Surgeon, Pennsylvania Hospital, Philadelphia, PA
Attending Surgeon, Hospital of the University of Pennsylvania, Philadelphia, PA
Member of Resident Work Hours Task Force, Department of Surgery, University of Pennsylvania Medical Center, Philadelphia, PA
Faculty Annual Giving Appeal Committee, University of Pennsylvania School of Medicine, Philadelphia, PA
Chairman, Thoracic Oncology Service Line, Penn Medicine - University of Pennsylvania Health System
Department: Surgery

Contact information
Division of Thoracic Surgery
Perelman School of Medicine, University of Pennsylvania
14th Floor South, PCAM
Philadelphia, PA 19104
Office: 2156624988
Fax: 2156156562
BCE (Chemical Engineering)
Villanova University, Villanova, PA, 1987.

Georgetown University, College of Arts and Science, Washington, DC , 1988.
University of Pennsylvania School of Medicine, Philadelphia, PA, 1992.
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Description of Research Expertise

Adjuvant Treatment for Lung cancer-clinical trials
Trimodality Treatment for Esophgeal cancer-clinical trials
Quality Outcome Measures in Thoracic Surgery
Benchmarking Outcomes in Thoracic Surgery
Thoracic Surgery Education

Description of Clinical Expertise

Surgery for Lung Cancer
Surgery For Esophgeal Cancer
Surgery of Mediasinal Disease
Surgery for Pleural Disease and Mesothelioma
Minimally Invasive Thoracic Surgery
Repair and Management of Esophageal Perforations
Complex Sugical resections for locally advanced lung and esophgeal cancer

Description of Other Expertise

Dr. Kucharczuk completed medical School, a general Surgery Residency and thoracic Surgery Training all at the University of Pennsylvania. His clinical and research interests focus on general thoracic surgery. He has expertise in the diagnosis and treatment of benign and malignant diseases of the chest including lung cancer, esophageal cancer, mesothelioma, and mediastinal tumors. He performs a high volume of traditional and minimally invasive thoracic surgical procedures at the Hospital of the University of Pennsylvania. He is an active member of the Thoracic Oncology Research Laboratory, serves as the educational coordinator for the Thoracic Surgery Service and is involved in a number of basic as well clinical research projects.

Selected Publications

Hanna A.N., Guajardo I., Williams N., Kucharczuk J., Dempsey D.T. : Hiatal Hernia after Esophagectomy: An Underappreciated Complication? J. Am. Coll. Surg. 230(4): 700-707, Jan 2020.

Goel N.J., Iyengar A., Kelly J.J., Mavroudis C., Lancaster C., Williams N.N., Dempsey D.T., Kucharczuk J. : Nationwide Analysis of 30-Day Readmissions After Esophagectomy: Causes, Costs, and Risk Factors. Annals of Thoracic Surgery 109(1): 185-193, Jan 2020.

Pani E., Kennedy G., Zheng X., Ukert B., Jarrar D., Gaughan C., Pechet T., Kucharczuk J., Singhal S. : Factors associated with nodal metastasis in 2-centimeter or less non–small cell lung cancer. J. Thorac. Cardiovasc. Surg. Oct 2019.

Rengan R., Mick R., Pryma D.A., Lin L.L., Christodouleas J., Plastaras J.P., Simone C.B., Gupta A.K., Evans T.L., Stevenson J.P., Langer C.J., Kucharczuk J., Friedberg J., Lam S., Patsch D., Hahn S.M., Maity A.: Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir with Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non-Small Cell Lung Cancer: A Phase 1/2 Trial JAMA Oncol. 5(10): 1464-1472, Oct 2019.

Predina J.D., Newton A.D., Corbett C., Shin M., Sulfyok L.F., Okusanya O.T., Delikatny E.J., Nie S., Gaughan C., Jarrar D., Pechet T., Kucharczuk J.C., Singhal S. : Near-infrared intraoperative imaging for minimally invasive pulmonary metastasectomy for sarcomas. J. Thorac. Cardiovasc. Surg. 157(5): 2061-2069, May 2019.

Predina J.D., Keating J., Newton A., Corbett C., Xia L., Shin M., Frenzel Sulyok L., Deshpande C., Litzky L., Nie S., Kucharczuk J.C., Singhal S.: A clinical trial of intraoperative near-infrared imaging to assess tumor extent and identify residual disease during anterior mediastinal tumor resection Clin. Lung Cancer 125(5): 807-817, Mar 2019.

Schonewolf C.A., Heskel M., Doucette A., Singhal S., Frick M.A., Xanthopoulos E.P., Corradetti M.N., Friedberg J.S., Pechet T.T., Christodouleas J.P., Levin W., Berman A., Cengel K.A., Verma V., Hahn S.M., Kucharczuk J.C., Rengan R., Simone C.B.: Five-year Long-term Outcomes of Stereotactic Body Radiation Therapy for Operable Versus Medically Inoperable Stage I Non–small-cell Lung Cancer: Analysis by Operability, Fractionation Regimen, Tumor Size, and Tumor Location. Clin. Lung Cancer 20(11), Jan 2019.

Predina J.D., Newton A.D., Corbett C., Xia L., Shin M., Sulfyok L.F., Okusanya O.T., Cengel K.A., Haas A., Litzky L., Kucharczuk J.C., Singhal S.: A Clinical Trial of TumorGlow to Identify Residual Disease During Pleurectomy and Decortication. Ann. Thorac. Surg. 107(1): 224-232, Jan 2019.

Kennedy G.T., Ukert B.D., Predina J.D., Newton A.D., Kucharczuk J.C., Polsky D., Singhal S.: Implications of Hospital Volume on Costs Following Esophagectomy in the United States. J. Gastrointest. Surg. 22(11): 1845-1851, Nov 2018.

Predina J.D., Newton A., Corbett C., Xia L., Sulyok L.F., Shin M., Deshpande C., Litzky L., Barbosa E., Low P.S., Kucharczuk J.C., Singhal S.: Localization of Pulmonary Ground-Glass Opacities with Folate Receptor-Targeted Intraoperative Molecular Imaging. J. Thorac. Oncol 13(7): 1028-1036, Nov 2018.

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Last updated: 04/29/2022
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