Robert E. Krisch, M.D., Ph.D.
Emeritus Associate Professor CE of Radiation Oncology
Department: Radiation Oncology
Contact information
Chester County Hospital
701 East Marshall Street
West Chester, PA 19380
701 East Marshall Street
West Chester, PA 19380
Office: 800-789-PENN (7366)
Education:
BA (Natural Sciences)
University of Pennsylvania, 1956.
M.D. (Medicine)
Temple University, 1960.
Ph.D.
University of Pennsylvania, 1964.
Permanent linkBA (Natural Sciences)
University of Pennsylvania, 1956.
M.D. (Medicine)
Temple University, 1960.
Ph.D.
University of Pennsylvania, 1964.
Selected Publications
Lee JH, Machtay MM, McKenna MG, Markiewicz DA, Krisch RE, Weinstein GS, Kligerman MM: : Radiotherapy with 6MV photons for early glottic carcinoma: potential impact of extension to the posterior vocal cord. Amer J Otolaryngol 22: 43-54, 2001.Ayene SI, Bernhard EJ, McKenna WG, Muschel R, Krisch RE, Koch CJ: DNA as a target in radiation induced apoptosis of myc and myc plus ras transfected rat embryo fibroblasts: a radiation chemistry approach for intact cells. Int. J. Radiat. Biol 76: 343-354, 2000.
Ayene SI, Koch CJ, Krisch RE: Modification of radiation induced single and double strand breaks by glutathione: Comparison of single and double strand breaks in SV40 DNA. Radiat Res 144: 1-8, 1998.
Ayene SI, Sullivan M, Krisch RE, Koch CJ: Protein derived radicals as sensitizers of radiation induced single and double strand DNA breaks. Radiat Res 148: 499-500, 1997.
Krisch RE, Ayene SI, Sullivan M, Koch CJ: A cell-like •OH scavenging environment alters the charge dependence of radiation protection by thiols. Radiat Res 148: 498-499, 1997.
Ayene SI, Koch CJ, Krisch RE: : Simulation of the cellular oxygen effect with an in vitro model system using double-strand DNA breaks as an endpoint. Radiat Res 146: 501-509, 1996.
Ayene SI, Koch CJ, Krisch RE: Role of scavenger-derived radicals in the induction of double strand breaks in irradiated DNA. Radiat Res 142: 133-143, 1995.
Krisch RE, Ayene SI, Koch CJ: Interaction of Thiol and Non-Thiol Scavengers in the Modification of Radiation-Induced DNA Damage. Radiation Damage in DNA: Structure/Function Relationships at Early Times. Fuciarelli, AF, & Zimbrick, JD, Eds (eds.). Battelle Press, Page: 383-391, 1995.
Sause WT, Scott C, Krisch R, Rotman M, Sneed PK, Janjan N, Davis L, Curran W, Choi KN, Selim H, Mohiuddin M, Grigsby P: Phase I/II trial of accelerated fractionation in brain metastases RTOG 85-28. Int J Radiat Oncol Biol Phys 26: 653-657, 1993.
Curran WJ, Scott CB, Horton J, Nelson JS, Weinstein AS, Fischbach AJ, Chang CH, Rotman M, Asbell SO, Krisch RE, Nelson DF: Recursive partitioning analysis of 1,578 on 3 Radiation Therapy Oncology Group (RTOG) malignant glioma trials. J Natl Cancer Inst 85: 704-710, 1993.