Susan M Domchek, MD

faculty photo
Basser Professor in Oncology
Department: Medicine

Contact information
Division of Hematology Oncology
10th Floor, South Pavilion
Office #10-150
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-615-3360
Fax: 215-615-3349
Education:
BA (Engineering Sciences)
Dartmouth College, 1990.
MD (Internal Medicine)
Harvard Medical School, 1995.
Permanent link
 
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Description of Research Expertise

Breast cancer genetics
Breast cancer prevention and screening
Breast cancer immunotherapy clinical trials

Description of Clinical Expertise

Breast cancer prevention, screening and treatment
Breast cancer genetics

Selected Publications

Hickey M, Moss KM, Brand A, Wrede CD, Domchek SM, Meiser B, Mishra GD, Joffe H. : What happens after menopause? (WHAM): A prospective controlled study of depression and anxiety up to 12 months after premenopausal risk-reducing bilateral salpingo-oophorectomy. Gynecol Oncol. February 2021 Notes: Epub ahead of print

Daly MB, Pal T, Berry MP, Buys SS, Dickson P, Domchek SM, Elkhanany A, Friedman S, Goggins M, Hutton ML; CGC, Karlan BY, Khan S, Klein C, Kohlmann W; CGC, Kurian AW, Laronga C, Litton JK, Mak JS; LCGC, Menendez CS, Merajver SD, Norquist BS, Offit K, Pederson HJ, Reiser G; CGC, Senter-Jamieson L; CGC, Shannon KM, Shatsky R, Visvanathan K, Weitzel JN, Wick MJ, Wisinski KB, Yurgelun MB, Darlow SD, Dwyer MA.: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 19(1): 77-102, January 2021.

Hu C, Hart SN, Gnanaolivu R, Huang H, Lee KY, Na J, Gao C, Lilyquist J, Yadav S, Boddicker NJ, Samara R, Klebba J, Ambrosone CB, Anton-Culver H, Auer P, Bandera EV, Bernstein L, Bertrand KA, Burnside ES, Carter BD, Eliassen H, Gapstur SM, Gaudet M, Haiman C, Hodge JM, Hunter DJ, Jacobs EJ, John EM, Kooperberg C, Kurian AW, Le Marchand L, Lindstroem S, Lindstrom T, Ma H, Neuhausen S, Newcomb PA, O'Brien KM, Olson JE, Ong IM, Pal T, Palmer JR, Patel AV, Reid S, Rosenberg L, Sandler DP, Scott C, Tamimi R, Taylor JA, Trentham-Dietz A, Vachon CM, Weinberg C, Yao S, Ziogas A, Weitzel JN, Goldgar DE, Domchek SM, Nathanson KL, Kraft P, Polley EC, Couch FJ. : A Population-Based Study of Genes Previously Implicated in Breast Cancer Engl J Med January 2021 Notes: Epub ahead of print

Lau-Min KS, Asher SB, Chen J, Domchek SM, Feldman M, Joffe S, Landgraf J, Speare V, Varughese LA, Tuteja S, VanZandbergen C, Ritchie MD, Nathanson KL. : Real-world integration of genomic data into the electronic health record: the PennChart Genomics Initiative. Genet Med. 2020 Dec 10. Genet Med December 2020 Notes: [Epub ahead of print]

Nadine M. Tung , MD; Mark E. Robson , MD; Steffen Ventz, PhD; Cesar A. Santa-Maria , MD, MSCI; Rita Nanda, MD; Paul K. Marcom, MD; Payal D. Shah, MD; Tarah J. Ballinger, MD; Eddy S. Yang , MD, PhD; Shaveta Vinayak, MD, MS; Michelle Melisko , MD; Adam Brufsky , MD, PhD; Michelle DeMeo, BS; Colby Jenkins , MS; Susan Domchek, MD; Alan D’Andrea, MD, Nancy U. Lin, MD; Melissa E. Hughes, MS; Lisa A. Carey, MD; Nick Wagle, MD, Gerburg M. Wulf , MD, PhD; Ian E. Krop, MD, PhD, Antonio C. Wolff, MD; Eric P. Winer, MD,and Judy E. Garber, MD, MPH: TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes Journal of Clinical Oncology October 2020 Notes: DOI: 10.1200/JCO.20.02151

Pace LE, Lee YS, Tung N, Hamilton JG, Gabriel C, Raja SC, Jenkins C, Braswell A, Domchek SM, Symecko H, Spielman K, Karlan BY, Lester J, Kamara D, Levin J, Morgan K, Offit K, Garber J, Keating NL. : Comparison of up-front cash cards and checks as incentives for participation in a clinician survey: a study within a trial. BMC Med Res Methodol. 20(1): 210, August 2020.

Kara N. Maxwell, MD,PhD; Brandon M. Wenz, B; Abha Kulkarni, MPH; Bradley Wubbenhorst, MS; Kurt D’Andrea, BS;Benita Weathers, MPH; Noah Goodman, MPH; Joseph Vijai, PhD; Jenna Lilyquist, PhD, Steven N. Hart, PhD;...Susan M. Domchek, MD; and Katherine L. Nathanson,MD: Mutation Rates in Cancer Susceptibility Genes in Patients With Breast Cancer With Multiple Primary Cancers. JCO Precision Oncology August 2020 Notes: Accepted on June 4,2020 and published at ascopubs.org/journal/po on August 19,2020: DOI https://doi.org/10.1200/PO.19. 00301.

Domchek SM, Postel-Vinay S, Im SA, Park YH, Delord JP, Italiano A, Alexandre J, You B, Bastian S, Krebs MG, Wang D, Waqar SN, Lanasa M, Rhee J, Gao H, Rocher-Ros V, Jones EV, Gulati S, Coenen-Stass A, Kozarewa I, Lai Z, Angell HK, Opincar L, Herbolsheimer P, Kaufman B. : Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA):an open-label, multicentre, phase 1/2, basket study. The Lancet Oncol. August 2020 Notes: [Epub ahead of print]

Maxwell KN, Wenz BM, Kulkarni A, Wubbenhorst B, D'Andrea K, Weathers B, Goodman N, Vijai J, Lilyquist J, Hart SN, Slavin TP, Schrader KA, Ravichandran V, Thomas T, Hu C, Robson ME, Peterlongo P, Bonanni B, Ford JM, Garber JE, Neuhausen SL, Shah PD, Bradbury AR, DeMichele AM, Offit K, Weitzel JN, Couch FJ, Domchek SM, Nathanson KL. : Mutation Rates in Cancer Susceptibility Genes in Patients With Breast Cancer With Multiple Primary Cancers. JCO Precis Oncol August 2020 Notes: 19;4:PO.19.00301.

Gallagher S, Hughes E, Wagner S, Tshiaba P, Rosenthal E, Roa BB, Kurian AW, Domchek SM, Garber J, Lancaster J, Weitzel JN, Gutin A, Lanchbury JS, Robson M. : Association of a Polygenic Risk Score With Breast Cancer Among Women Carriers of High- And Moderate-Risk Breast Cancer Genes. JAMA 7(3), July 2020.

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Last updated: 02/23/2021
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