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Juan E. Grunwald, MD

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Emeritus Professor CE of Ophthalmology
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Assistant in Ophthalmology, Penn Presbyterian Medical Center
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Attending Staff Physician, Hospital of the Uniersity of Pennsylvania
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Attending Staff Physician, Children's Hospital of Philadelphia
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Member, Medical Records Committee, Penn Presbyterian Medical Center, University of Pennsylvania
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Director, Vivian S. Lasko Ocular Vascular Laboratory, Scheie Eye Institute
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Department: Ophthalmology
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46 Contact information
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Scheie Eye Institute
1c 51 North 39th Street
27 2689
Philadelphia, PA 19104
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18 Publications
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13 Education:
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47 University of Tel-Aviv, Sackler Medical School, 1975.
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Description of Research Expertise

263 Dr. Grunwald is world renowned for his research on blood flow in the retina. He has helped to develop techniques to measure the circulation in the eye. In his laboratory, the Vivian Simkins Lasko Retinal Vascular Research Laboratory, non-invasive state of the art technology is employed to study the role of circulatory changes in the development of vision-threatening eye diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma, retinitis pigmentosa, and others and the pharmacologic effects of medications on the human ocular vasculature and its circulation.
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1e Clinical Trials
40 Dr. Grunwald is an investigator on the following trials:
54 •Complications of Age-Related Macular Degeneration Prevention Trial (CAPT)
56 •The Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
3d •Retinopathy in Chronic Renal Insufficiency (RCRIC)
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c4 He is the Principal Investigator of two grants that will quantitate changes occurring in the retina due to diabetic retinopathy, systemic hypertension and age-related macular degeneration.
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cf Age-related macular degeneration (AMD), choroidal circulation, diabetic retinopathy, ocular vasculature, optic nerve blood flow, pharmacologic effects, retina, retinal circulation, retinal vasculature
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Description of Clinical Expertise

158 Dr. Grunwald cares for and treats patients with age-related macular degeneration, diabetic retinopathy and retinal vascular diseases at the following locations: Scheie Eye Institute, Hospital of the University of Pennsylvania, Penn Medicine at Radnor, Mercy Fitzgerald Hospital and the Veterans’ Administration Medical Center.
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Description of Other Expertise

41 Teaching. Fluency in Spanish, Hebrew and English
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Selected Publications

14f Cuilla TA, Ying GS, Maguire MG, Martin DF, Jaffe GJ, Grunwald JE, Daniel E, Toth CA: Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 122(6): 1203-11, Jun 2015.

 179 Altaweel MM, Daniel E, Martin DF, Mittra RA, Grunwald JE, Lai MM, Melamud A, Morse LS, Huang J, Ferris FL, Fine SL, Maguire MG: Outcomes of eyes with lesions composed of >50% blood in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 122(2): 391-398.e5, Feb 2015.

 151 Gewaily DY, Grunwald JE, Pistilli M, Ying GS, Maguire MG, Daniel E, Ostroff CP, Fine SL: Delayed patchy choroidal filling in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). American journal of ophthalmology 158(3): 525-31.e2, Sep 2014.

 196 Ricardo AC, Grunwald JE, Parvathaneni S, Goodin S, Ching A, Lash JP: Retinopathy and CKD as predictors of all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 1988-1994. American journal of kidney diseases : the official journal of the National Kidney Foundation 64(2): 198-203, Aug 2014.

 159 Ying GS, Kim BJ, Maguire MG, Huang J, Daniel E, Jaffe GJ, Grunwald JE, Blinder KJ, Flaxel CJ, Rahhal F, Regillo C, Martin DF: Sustained visual acuity loss in the comparison of age-related macular degeneration treatments trials. JAMA ophthalmology 132(8): 915-21, Aug 2014.

 139 Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Huang J, Ying GS, Hagstrom SA, Winter K, Maguire MG: Risk of scar in the comparison of age-related macular degeneration treatments trials. Ophthalmology 121(3): 656-66, Mar 2014.

 17c Scialla JJ, Xie H, Rahman M, Anderson AH, Isakova T, Ojo A, Zhang , Nessel L, Hamano T, Grunwald JE, Raj DS, Yang W, He J, Lash JP, Go AS, Kusek JW, Feldman H, Wolf M: Fibroblast growth factor-23 and cardiovascular events in CKD. Journal of the American Society of Nephrology : JASN 25(2): 349-60, Feb 2014.

 188 Maguire MG, Daniel E, Shah AR, Grunwald JE, Hagstrom SA, Avery RL, Huang J, Martin RW, Roth DB, Castellarin AA, Bakri SJ, Fine SL, Martin DF: Incidence of Choroidal Neovascularization in the Fellow Eye in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 120(10): 2035-2041, Oct 2013.

 15b Grunwald JE, Daniel E, Huang J, Ying GS, Maguire MG, Toth CA, Jaffe GJ, Fine SL, Blodi B, Klein ML, Martin AA, Hagstrom SA, Martin DF: Risk of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 121(1): 150-61, Sep 2013.

 132 Jaffe GJ, Martin DF, Toth CA, Daniel E, Maguire MG, Ying GS, Grunwald JE, Huang J: Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 120(9): 1860-70, Sep 2013.

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