Bert W. O'Malley Jr., M.D.

faculty photo
Emeritus Professor of Otorhinolaryngology: Head and Neck Surgery
Department: Otorhinolaryngology: Head and Neck Surgery

Contact information
Univ PA Health System
Department of Otorhinolaryngology - Head and Neck Surgery
5 Ravdin
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-349-5383
Fax: 215-615-4334

University of Notre Dame, 1981.
(Bachelor of Arts in Biochemistry)
University of Texas, 1984.
University of Texas Southwestern Medical School, M.D., 1988.
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Description of Research Expertise

Gene and Molecular Therapy

Description of Clinical Expertise

Skull Base Surgery
Trans Oral Robotic Surgery - Tonsil/Tongue
Sinus and Nasal Tumors
Parotid Tumors
Head and Neck Cancer

Description of Other Expertise

Dr. O'Malley has served as PI on three NIH RO1s and an R29 (FIRST) award as well as numerous industry and foundation grants. He is pioneering the use of molecular therapies to enhance the anti-tumor effects of chemotherapy and radiation while reducing the known toxicities of these treatments. In addition, he is investigating novel combinations of stem cells and biomatrices for tissue defect reconstruction. He is currently Co-PI of the NIH-funded Penn Multidisciplinary Consortium: Personalized Dental, Oral and Craniofacial Tissue Regeneration.

Selected Publications

Shanti Rabie M, O'Malley Bert W: Surgical Management of Oral Cancer. Dental clinics of North America 62(1): 77-86, Jan 2018.

Hatten Kyle M, Brody Robert M, Weinstein Gregory S, Newman Jason G, Bur Andres M, Chalian Ara A, OʼMalley Bert W, Rassekh Christopher H, Cannady Steven B: Defining the Role of Free Flaps for Transoral Robotic Surgery. Annals of plastic surgery 80(1): 45-49, Jan 2018.

Bur Andrés M, Gomez Ernest D, Newman Jason G, Weinstein Gregory S, O'Malley Bert W, Rassekh Christopher H, Kuchenbecker Katherine J: Evaluation of high-fidelity simulation as a training tool in transoral robotic surgery. The Laryngoscope 127(12): 2790-2795, Dec 2017.

Routman David M, Funk Ryan K, Tangsriwong Kanograt, Lin Alexander, Keeney Michael G, García Joaquín J, Zarka Matthew A, Lewis Jason T, Stoddard David G, Moore Eric J, Day Courtney N, Zhai Qihui, Price Katharine A, Lukens John N, Swisher-McClure Samuel, Weinstein Gregory S, O'Malley Bert W, Foote Robert L, Ma Daniel J: Relapse Rates With Surgery Alone in Human Papillomavirus-Related Intermediate- and High-Risk Group Oropharynx Squamous Cell Cancer: A Multi-Institutional Review. International journal of radiation oncology, biology, physics 99(4): 938-946, Nov 2017.

Ahn Peter H, Finlay Jarod C, Gallagher-Colombo Shannon M, Quon Harry, O'Malley Bert W, Weinstein Gregory S, Chalian Ara, Malloy Kelly, Sollecito Thomas, Greenberg Martin, Simone Charles B, McNulty Sally, Lin Alexander, Zhu Timothy C, Livolsi Virginia, Feldman Michael, Mick Rosemarie, Cengel Keith A, Busch Theresa M: Lesion Oxygenation Associates with Clinical Outcomes in Premalignant and Early Stage Head and Neck Tumors Treated on a Phase 1 Trial of Photodynamic Therapy. Photodiagnosis and photodynamic therapy 21: 28-35, Nov 2017.

Kayyali Mohammad N, Wright Alexander C, Ramsey Andrew J, Brant Jason A, Stein Joel M, O'Malley Bert W, Li Daqing: Challenges and opportunities in developing targeted molecular imaging to determine inner ear defects of sensorineural hearing loss. Nanomedicine : nanotechnology, biology, and medicine 14(2): 397-404, Oct 2017.

Banerjee Sagarika, Tian Tian, Wei Zhi, Peck Kristen N, Shih Natalie, Chalian Ara A, O'Malley Bert W, Weinstein Gregory S, Feldman Michael D, Alwine James, Robertson Erle S: Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas. Scientific reports 7(1): 4036, Jun 2017.

Ojerholm Eric, Lukens J Nicholas, Ahn Peter H, Geiger Geoffrey, Swisher-McClure Samuel, Newman Jason, Chalian Ara, Weinstein Gregory, O'Malley Bert W, Cohen Roger, Lin Alexander: Benefits of omitting primary site radiation therapy after transoral robotic surgery: Only time will tell. Practical radiation oncology 7(3): e157-e158, May - Jun 2017.

Xu Qilin, Shanti Rabie M, Zhang Qunzhou, Cannady Steven B, O'Malley Bert W, Le Anh D: A Gingiva-Derived Mesenchymal Stem Cell-Laden Porcine Small Intestinal Submucosa Extracellular Matrix Construct Promotes Myomucosal Regeneration of the Tongue. Tissue engineering. Part A 23(7-8): 301-312, Apr 2017.

Hatten Kyle M, O'Malley Bert W, Bur Andres M, Patel Mihir R, Rassekh Christopher H, Newman Jason G, Cannady Steven B, Chalian Ara A, Hodnett Benjamin L, Lin Alexander, Lukens John N, Cohen Roger B, Bauml Joshua M, Montone Kathleen T, Livolsi Virginia A, Weinstein Gregory S: Transoral Robotic Surgery-Assisted Endoscopy With Primary Site Detection and Treatment in Occult Mucosal Primaries. JAMA otolaryngology-- head & neck surgery 143(3): 267-273, Mar 2017.

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Last updated: 01/25/2019
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