Marie A Guerraty, MD, PhD
Assistant Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania
Member, ITMAT
Department: Medicine
Graduate Group Affiliations
Contact information
11-103 Smilow Center for Translational Research
3400 Civic Center Blvd
Philadelphia, PA 19104
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-746-1449
Education:
BS (Mathematics)
Duke University, Durham, NC, 2003.
PhD (Bioengineering)
University of Pennsylvania School of Engineering and Applied Sciences, 2008.
MD (Medicine)
University of Pennsylvania Perelman School of Medicine, 2010.
Permanent linkBS (Mathematics)
Duke University, Durham, NC, 2003.
PhD (Bioengineering)
University of Pennsylvania School of Engineering and Applied Sciences, 2008.
MD (Medicine)
University of Pennsylvania Perelman School of Medicine, 2010.
Description of Clinical Expertise
cardiac imaging, cardiac PET, myocardial blood flow, transthoracic echocardiography, ischemic heart disease, coronary artery disease, coronary microvascular diseaseDescription of Research Expertise
ischemic heart disease, vascular biology, coronary artery disease, vascular biology, coronary microvascular disease, nuclear cardiology, Perfusion PET, small animal cardiac imaging, functional genomics, transcriptional regulation, FOG2, ZFPM2, TWIST1Selected Publications
Donna M. Conlon 1,Siri Kanakala 1,Tess Cherlin 2ORCID,Yi-An Ko 3,Cecilia Vitali 1,Sharavana Gurunathan 1ORCID,Rasika Venkatesh 3ORCID,Jakob Woerner 4,Lindsay A. Guare 2ORCID,Penn Medicine Biobank 5,Anurag Verma 1,Shefali S. Verma 2 andMarie A. Guerraty 1,*: Genotype-First Approach Identifies an Association between rs28374544/FOG2S657G and Liver Disease through Alterations in mTORC1 Signaling. Genes 2024.Welch E, Guerraty MA, ..., Ky B, Narayan V.: Coronary Microvascular Dysfunction in Men with Prostate Cancer Receiving Androgen-Deprivation Therapy. Clinical Genitourinary Cancer 2024.
Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V Schneider, Delfin G Buyco, Chelsea Lin, Blanca E Himes, Clementina A Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E Furth, Jeffrey T Billheimer, Nicholas J Hand, David E Kaplan, Kyong-Mi Chang, Philip S Tsao, Julie A Lynch, Joseph L Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C Phillips, Daniel J Rader, Rotonya M Carr: A Missense Variant in Human Perilipin 2 (Plin2 Ser251pro) Reduces Hepatic Steatosis In Mice. JHEP Reports Oct 2023 Notes: in press.
Lindsay C Johnson, Marie A Guerraty, Stephen C Moore, Scott D Metzler: Determining the effect of cardiac blood volume on accuracy of uptake rate constants by simulation. Phys Med Biol 68(20): 10.1088/1361-6560/ace0f1, Oct 4 2023.
Pankhuri Singhal, Lindsay Guare, Colleen Morse, DPT, Anastasia Lucas, Marta Byrska-Bishop, Marie A. Guerraty, Dokyoon Kim, Marylyn D. Ritchie, Anurag Verma: DETECT: Feature extraction method for disease trajectory modeling in electronic health records. AMIA Joint Summits on Transl Sci Proc 16(2023): 487-496, Jun 2023.
Wenjian Lv, Apoorva Babu, Michael P. Morley, Kirin Musunuru, Marie Guerraty: A Resource of Gene Expression Data from a Multiethnic Population Cohort of Induced Pluripotent Cell–Derived Cardiomyocytes. Biorxiv May 2023.
Sharavana Gurunathan, Marie Guerraty: Translational Insights in Coronary Microvascular Disease. J Am Coll Cardiol Basic Trans Science 8(5): 515-517, May 2023.
Guerraty MA, Verma Shefali, Ko YA, McQuillan MA, Conlon D, Tobias JW, Levin MG, Haury W, Zhang C, Judy R, Regeneron Genomics Center, PennMedicine Biobank, Tishkoff S, Damrauer SM, Arany Z, Rader DJ: FOG2 coding variant Ser657Gly is associated with Coronary Microvascular Disease through altered hypoxia-mediated gene transcription. MedRxiv May 2023.
JM Ortega-Legaspi, M Molina, J Leon, A Cunningham, M Guerraty, E Peyster, H Julien, R McLean, L Goldberg, P Bravo: Coronary Flow Reserve is an Independent Predictor of Major Adverse Cardiovascular Events in Long Term Heart Transplantation Survivors. The Journal of Heart and Lung Transplantation 42(4): S78, Apr 2023.
Marie Guerraty, Zoltan Arany: A call for a unified view of coronary microvascular disease. Trends in Cardiovascular Medicine 1738(23): 1-4, Jan 2023.