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Giorgos C Karakousis, MD

Giorgos C Karakousis, MD

faculty photo
Assistant Professor of Surgery at the Hospital of the University of Pennsylvania
Department: Surgery

Contact information
Division of Endocrine & Oncologic Surgery
Hospital of the University of Pennsylvania
3400 Spruce St., 4 Silverstein
Philadelphia, PA 19104
Office: 215-662-2083
Fax: 215-662-7476
Education:
BS, MS (Molecular Biophysics and Biochemistry)
Yale University, 1996.
MD
University of Pennsylvania School of Medicine, 2001.
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Selected Publications

Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA: The state of melanoma: challenges and opportunities. Pigment Cell Melanoma Research Apr. 17 2016 Notes: [Epub ahead of print]

Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, Meeth K, Tang HY, Yin X, Wood WH, Lehrmann E, Becker KG, Flaherty KT, Frederick DT, Wargo JA, Cooper ZA, Tetzlaff MT, Hudgens C, Aird KM, Zhang R, Xu X, Liu Q, Bartlett E, Karakousis G, Eroglu Z, Lo RS, Chan M, Menzies AM, Long GV, Johnson DB, Sosman J, Schilling B, Schadendorf D, Speicher DW, Bosenberg M, Ribas A, Weeraratna AT: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature Apr. 2016 Notes: (Epub ahead of print).

Zhang G, Frederick DT, Wu L, Wei Z, Krepler C, Srinivasan S, Chae YC, Xu X, Choi H, Dimwamwa E, Ope O, Shannan B, Basu D, Zhang D, Guha M, Xiao M, Randell S, Sproesser K, Xu W, Liu J, Karakousis GC, Schuchter LM, Gangadhar TC, Amaravadi RK, Gu M, Xu C, Ghosh A, Xu W, Tian T, Zhang J, Zha S, Liu Q, Brafford P, Weeraratna A, Davies MA, Wargo JA, Avadhani NG, Lu Y, Mills GB, Altieri DC, Flaherty KT, Herlyn M: Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors. Journal of Clinical Investigation Apr. 2016 Notes: (Epub ahead of print).

Marek AJ, Ming ME, Bartlett EK, Karakousis GC, Chu EY: Acral lentiginous histologic subtype and sentinel lymph node positivity in thin melanoma. JAMA Dermatology Apr. 20 2016 Notes: (Epub ahead of print).

Datta J, McMillan MT, Ruffolo L, Lowenfeld L, Mamtani R, Plastaras JP, Dempsey DT, Karakousis GC, Drebin JA, Fraker DL, Roses RE: Multimodality therapy improves survival in resected early stage gastric cancer in the United States. Annals of Surgical Oncology Apr. 18 2016 Notes: (Epub ahead of print).

Budina-Kolomets A, Webster MR, Leu JI, Jennis M, Krepler C, Guerrini A, Kossenkov AV, Xu W, Karakousis GC, Schuchter LM, Amaravadi RK, Wu H, Yin X, Liu Q, Lu Y, Mills GB, Xu X, George DL, Weeraratna AT, Murphy ME: HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors. Cancer Research Mar. 2016 Notes: (Epub).

Ecker BL, McMillan MT, Datta J, Mamtani R, Giantonio BJ, Dempsey DT, Fraker DL, Drebin JA, Karakousis GC, Roses RE: Efficacy of adjuvant chemotherapy for small bowel adenocarcinoma: A propensity score-matched analysis. Cancer 122(5): 693-701, Mar. 2016 Notes: (Epub Dec. 30, 2015).

Kuo LE, Simmons KD, Wachtel H, Zaheer S, Karakousis GC, Fraker DL, Kelz RR: Racial disparities in initial presentation of benign thyroid disease for resection. Annals of Surgical Oncology Mar. 2016 Notes: (Epub ahead of print).

Newton AD, Bartlett EK, Karakousis GC: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a review of factors contributing to morbidity and mortality. Journal of Gastrointestinal Oncology 7(1): 99-111, Feb. 2016.

Neuwirth MG, Alexander HR, Karakousis GC: Then and now: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), a historical perspective. Journal of Gastrointestinal Oncology 7(1): 18-28, Feb. 2016.

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Last updated: 05/02/2016
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