Frank E. Silvestry, M.D.
Associate Professor of Medicine at the Hospital of the University of Pennsylvania
Program Director, Cardiovascular Disease Fellowship Program, Hospital of the University of Pennsylvania
Associate Chief for Education, Cardiovascular Division, Perelman School of Medicine
Department: Medicine
Contact information
Cardiovascular Division
Department of Medicine
11-133 South Pavillion PCAM
3400 Civic Center Boulevard
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Department of Medicine
11-133 South Pavillion PCAM
3400 Civic Center Boulevard
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Office: 215 615 5236
Fax: 215 349 8190
Fax: 215 349 8190
Publications
Education:
B.S. (Biochemistry)
State University of New York at Binghamton, 1986.
M.D. (Medicine)
University of Pennsylvania, 1990.
Permanent linkB.S. (Biochemistry)
State University of New York at Binghamton, 1986.
M.D. (Medicine)
University of Pennsylvania, 1990.
Description of Research Expertise
Mitral Valve DiseasePatent Foramen Ovale
Atrial Septal Defect
Structural heart disease
Valvular heart disease
Cardiac Imaging
Intracardiac Echocardiography
Interventional Echocardiography
Description of Clinical Expertise
Mitral Valve DiseasePatent Foramen Ovale
Atrial Septal Defect
Intracardiac Echocardiography
Interventional Echocardiography
Valvular heart disease
Preventitive cardiology
Lipid abnormalities
Metabolic syndrome
Selected Publications
Litwin SE, Komtebedde J, Hu M, Burkhoff D, Hasenfuß G, Borlaug BA, Solomon SD, Zile MR, Mohan RC, Khawash R, Sverdlov AL, Fail P, Chung ES, Kaye DM, Blair J, Eicher JC, Hummel SL, Zirlik A, Westenfeld R, Hayward C, Gorter TM, Demers C, Shetty R, Lewis G, Starling RC, Patel S, Gupta DK, Morsli H, Penicka M, Cikes M, Gustafsson F, Silvestry FE, Rowin EJ, Cutlip DE, Leon MB, Kitzman DW, Kleber FX, Shah SJ; REDUCE LAP-HF Investigators and Research Staff.: Exercise-Induced Left Atrial Hypertension in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail Mar 2023.Gard EK, Beale AL, Telles F, Silvestry FE, Hanff T, Hummel SL, Litwin SE, Petrie MC, Shah SJ, Borlaug BA, Burkhoff D, Komtebedde J, Kaye DM, Nanayakkara S.: Left atrial enlargement is associated with pulmonary vascular disease in heart failure with preserved ejection fraction. Eur J Heart Fail Feb 2023.
Borlaug BA, Blair J, Bergmann MW, Bugger H, Burkhoff D, Bruch L, Celermajer DS, Claggett B, Cleland JGF, Cutlip DE, Dauber I, Eicher JC, Gao Q, Gorter TM, Gustafsson F, Hayward C, van der Heyden J, Hasenfuß G, Hummel SL, Kaye DM, Komtebedde J, Massaro JM, Mazurek JA, McKenzie S, Mehta SR, Petrie MC, Post MC, Nair A, Rieth A, Silvestry FE, Solomon SD, Trochu JN, Van Veldhuisen DJ, Westenfeld R, Leon MB, Shah SJ; REDUCE LAP-HF-II Investigators.: Latent Pulmonary Vascular Disease May Alter the Response to Therapeutic Atrial Shunt Device in Heart Failure. Circulation 145: 1592-1604, May 2022.
Kodali S, Hahn RT, George I, Davidson CJ, Narang A, Zahr F, Chadderdon S, Smith R, Grayburn PA, O'Neill WW, Wang DD, Herrmann H, Silvestry F, Elmariah S, Inglessis I, Passeri J, Lim DS, Salerno M, Makar M, Mack MJ, Leon MB, Makkar R; TRISCEND Investigators.: Transfemoral Tricuspid Valve Replacement in Patients With Tricuspid Regurgitation: TRISCEND Study 30-Day Results. JACC Cardiovasc Interv 15: 471-480, Mar 2022.
Webb J, Hensey M, Fam N, Rodés-Cabau J, Daniels D, Smith R, Szeto W, Boone R, Ye J, Moss R, Peterson M, Ong G, Paradis JM, Dagenais F, Wintzer-Wehekind J, Shafi B, Nair D, Szerlip M, Grayburn P, Silvestry F, Koulogiannis K, Hermiller J, Guyton R, Herrmann H.: Transcatheter Mitral Valve Replacement With the Transseptal EVOQUE System. JACC Cardiovasc Interv 13: 2418-2426, Oct 2020.
Reza N, Adusumalli S, Saybolt MD, Silvestry FE, Sanghavi M, Lewey J, Ambrose M.: Implementing a Women's Cardiovascular Health Training Program in a Cardiovascular Disease Fellowship: The MUCHACHA Curriculum. JACC Case Rep 2: 164-167, Jan 2020.
Chao, Ariana M, Wadden, Thomas A, Berkowitz, Robert I, Quigley, Kerry, Silvestry, Frank: The risk of cardiovascular complications with current obesity drugs. Expert opinion on drug safety. Taylor & Francis, 19(9): 1095-1104, 2020.
Chao AM, Wadden TA, Berkowitz RI, Quigley K, Silvestry F.: The risk of cardiovascular complications with current obesity drugs. Expert Opin Drug Saf 2020.
Webb, John, Hensey, Mark, Fam, Neil, Rodés-Cabau, Josep, Daniels, David, Smith, Robert, Szeto, Wilson, Boone, Robert, Ye, Jian, Moss, Robert, Peterson, Mark, Ong, Geraldine, Paradis, Jean-Michel, Dagenais, François, Wintzer-Wehekind, Jérôme, Shafi, Bilal, Nair, Deepu, Szerlip, Molly, Grayburn, Paul, Silvestry, Frank, Koulogiannis, Konstantinos, Hermiller, James, Guyton, Robert, Herrmann, Howard: Transcatheter Mitral Valve Replacement With the Transseptal EVOQUE System. JACC. Cardiovascular interventions 13(20): 2418-2426, 2020.
Kay J, Reza N, Silvestry FE.: Establishing and Expecting a Culture of Support for Breastfeeding Cardiology Fellows. JACC Case Rep 1: 680-683, Dec 2019.