Jonas S. Johansson, MD PhD

Emeritus Associate Professor of Anesthesiology and Critical Care
Department: Anesthesiology and Critical Care
Contact information
HUP - 6 DULLES
3400 Spruce Street
Philadelphia, PA 19104
3400 Spruce Street
Philadelphia, PA 19104
Office: 2153495344
Email:
JOHANSSO@MAIL.MED.UPENN.EDU
JOHANSSO@MAIL.MED.UPENN.EDU
Education:
BS
University of Miami, 1984.
M.D.
University of Miami, 1990.
Ph.D. (Pharmacology)
University of Miami, 1990.
Permanent linkBS
University of Miami, 1984.
M.D.
University of Miami, 1990.
Ph.D. (Pharmacology)
University of Miami, 1990.
Selected Publications
Johansson JS, Solt K, Reddy KS: Binding of the general anesthetics chloroform and 2,2,2-trichloroethanol to the hydrophobic core of a four-a-helix bundle protein. Photochem Photobiol 77: 20-26, 2003.Johansson JS, Manderson GA: Aromatic amino acid side-chain structure dictates halothane binding energetics. Alcohol Clin Exp Res 2003 Notes: in press.
Manderson GA, Michalsky SJ, Johansson JS: Effects of alanine-to-valine substitutions on the binding of halothane and chloroform to a four-a-helix bundle. Biophys J 2003 Notes: in press.
Johansson JS: Noninactivating tandem pore domain potassium channels as attractive targets for general anesthetics. Anesth Analg 2003 Notes: in press.
Chan K, Meng QC, Johansson JS, Eckenhoff RG: Low-affinity analytical chromatography for measuring inhaled anesthetic binding to isolated proteins. Anal Biochem 301: 3008-313, 2002.
Solt K, Johansson JS: Binding of the active metabolite of chloral hydrate, 2,2,2-trichloroethanol, to serum albumin demonstrated using tryptophan fluorescence quenching. Pharmacology 24: 152-159, 2002.
Chapeaurouge A, Johansson JS, Ferreira ST: Folding of a de novo designed four-helix bundle protein. J Biol Chem 277: 16478-16483, 2002.
Manderson GA, Johansson JS: The role of aromatic side chains in the binding of volatile general anesthetics to a four-a-helix bundle. Biochemistry 41: 4080-4087, 2002.
Meng QC, Johansson JS, Eckenhoff RG: A chromatographic approach to the determination of relative drug membrane permeability. J Chromatogr B Biomed Appl 744: 89-95, 2002.
Johansson JS, Manderson GA: The role of aromatic side chains in the binding of volatile general anesthetics to a four-alpha-helix bundle. Biophys J 82: A1617, 2002.