Gregory P Bisson, MD, MSCE
Associate Professor of Medicine (Infectious Diseases)
Senior Scholar, Department of Biostatistics and Epidemiology, Perelman School of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
832 Blockley Hall
423 Guardian Drive
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania
Philadelphia, PA 19104-6021
423 Guardian Drive
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania
Philadelphia, PA 19104-6021
Office: 215-573-5811
Fax: 215-573-5315
Fax: 215-573-5315
Education:
BA (Japanese)
University of Wisconsin-Madison, 1992.
MD
University of Minnesota School of Medicine, 1997.
MSCE (Epidemiology)
Perelman School of Medicine, University of Pennsylvania, 2006.
Permanent linkBA (Japanese)
University of Wisconsin-Madison, 1992.
MD
University of Minnesota School of Medicine, 1997.
MSCE (Epidemiology)
Perelman School of Medicine, University of Pennsylvania, 2006.
Description of Research Expertise
My research is dedicated to improving treatment outcomes of patients with HIV and tuberculosis (TB) and other AIDS-associated opportunistic infections. Current research projects are evaluating the relationship between very early virologic and immunologic response to antiretroviral therapy and clinical outcomes in adults with HIV/TB. Many patients with advanced HIV die soon after antiretroviral therapy initiation, and our research group focuses on trying to understand the pathophysiologic and social mechanisms underlying these early deaths. In addition, we are pursuing translational projects evaluating novel host-directed therapies for treatment of drug resistant TB.Selected Publications
Meghji J, Auld SC, Bisson GP, Khosa C, Masekela R, Navuluri N, Rachow A: Post-tuberculosis lung disease: Towards prevention, diagnosis and care. Lancet Respir Med. 21(24): 00429-6. Mar 2025 Notes: DOI: 10.1016/S2213-2600(24)00429-6.Auld SC, Queiroz ATL, Araujo-Pereira M, Maenetje P, Mofokeng N, Mngomezulu L, Masilela D, Dobosh B, Tirouvanziam R, Kornfeld H, Andrade B, Bisson GP: Inflammatory profiles in sputum and blood of people with TB with and without HIV coinfection. Tuberculosis 151, Mar 2025 Notes: DOI: 10.1016/j.tube.2025.102612.
Auld SC, Bisson GP: Post-TB sequelae and the burden of “Long TB”: continuing TB care after treatment completion. American Journal of Respiratory and Critical Care Medicine 2025 Notes: In press.
Richterman A, Sinha P, Ivers LC, Gross R, Rantleru T, Tamuhla N, Bisson GP: Food Insecurity and Undernutrition Are Associated With Distinct Immunologic Profiles in People With Tuberculosis and Advanced HIV Starting Antiretroviral Therapy. J Acquir Immune Defic Syndr 95(5): 494-504, Apr 2024.
Maenetje P, Baik Y, Schramm DB, Vangu MDW, Wallis RS, Mlotshwa M, Tiemessen CT, Li Y, Kornfeld H, Churchyard G, Auld SC, Bisson GP: Circulating biomarkers, FeNO, and lung function in patients with HIV and tuberculosis. J Infect Dis 229(3): 824-832, Mar 2024.
Allwood BW, Nightingale R, Agbota G, Auld S, Bisson GP, Byrne A, Dunn R, Evans D, Hoddinott G, Günther G, Islam Z, Johnston JC, Kalyatanda G, Khosa C, Marais S, Makanda G, Mashedi OM, Meghji J, Mitnick C, Mulder C, Nkereuwem E, Nkereuwem O, Ozoh OB, Rachow A, Romanowski K, Seddon JA, Schoeman I, Thienemann F, Walker NF, Wademan DT, Wallis R, van der Zalm MM: Perspectives from the 2nd International Post-Tuberculosis Symposium: mobilising advocacy and research for improved outcomes. International Journal of Tuberculosis and Lung Disease 1(3): 111-123, Mar 2024.
Labuda SM, Seaworth B, Dasgupta S, Goswami ND, Haley C, Ashkin D, Hatsengate D, Cropper T, Semidey AC, Darnall E, Macias P, Jasuja S, Wegner P, Landers K, Yu S, Soukup J, Narita M, DeSilva M, Armitige L, Corriveau E, Schechter M, Bisson GP, Sanchez A, Cummins J, Lindsey JA, Easton AV, Dworkin FF, Nilsen D, Lardizabal AA: Bedaquiline, pretomanid, and linezolid with or without moxifloxacin. Lancet Respir Med. 12(2): e5-e6, Feb 2024.
Winters N, Schnitzer ME, Campbell JR, Ripley S, Winston C, Savic R, Ahmad N, Bisson G, Dheda K, Esmail A, Gegia M, Monedero I, Dalcolmo MP, Rodrigues D, Singla R, Yim JJ, Menzies D.: Identifying patients with multidrug-resistant tuberculosis who may benefit from shorter durations of treatment. PLoS One 18(10): e0292106, Oct 2023.
Araújo-Pereira M, Krishnan S, Salgame P, Manabe YC, Hosseinipour MC, Bisson GP , Damocles PS, Rouzier S, Leong S, Mave V, Kipyego Sawe F, Siika AM , Kanyama C, Dadabhai SS, Lama JR, Valencia-Huamani J, Badal-Faesen S, Lalloo UG, Naidoo N, Mohapi L, Kityo C, Andrade B , Gupta A: Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER trial. EClinical Medicine 60: 102030, Jun 2023.
Baik Y, Maenetje P, Schramm D, Tiemessen C, Ncube I, Churchyard G, Wallis R, Vangu MD, Kornfeld H, Li Y, Auld SC, Bisson GP: Lung function and collagen 1a levels are associated with changes in six-minute walk test distance during treatment of TB among HIV-infected adults: a prospective cohort study BMC Pulmonary Medicine 23(1): 53, Feb 2023.