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Natalie E. Rintoul, MD
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Professor of Clinical Pediatrics (Neonatology & Newborn Services)
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Attending Physician, Children's Hospital of Philadelphia
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Fetal Consultant, Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia
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ECMO Resource Attending, Children's Hospital of Philadelphia
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Medical Director, Neonatal Extracorporeal Membrane Oxygenation (ECMO), Children's Hospital of Philadelphia
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Medical Director, Neonatal Surgical Service, Children's Hospital of Philadelphia
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Medical Co-Director Neonatal SDU Service, Children's Hospital of Philadelphia
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Department: Pediatrics
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Contact information
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Children's Hospital of Philadelphia
21 Department of Neonatology
42 34th and Civic Center Boulevard
Philadelphia, PA 19104
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21 Department of Neonatology
42 34th and Civic Center Boulevard
Philadelphia, PA 19104
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Email:
rintoul@email.chop.edu
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rintoul@email.chop.edu
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Education:
21 5 1c (General Science) c
2a McGill University, 1987.
21 7 BS 14 (Science) c
2b Queen's University, 1991.
21 7 MD c
2b Queen's University, 1995.
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Permanent link21 5 1c (General Science) c
2a McGill University, 1987.
21 7 BS 14 (Science) c
2b Queen's University, 1991.
21 7 MD c
2b Queen's University, 1995.
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3d Protocol Name: Reintubation of post surgical neonates
17 PI: David Cohen
25 Study Contact Theodora Goebel
3b Primary Funder: Children's Anesthesiology Associate
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40 Fetal Tracheal Occlusion Congenital Diaphragmatic Hernia
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10 IRB 3779
24 Pulmonary Hypoplasia Program
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15 Milrinone IRB
19 Gastroschisis IRB
37 Maternal Progesterone/Fetal Neuroprotection IRB
21 Gastroschisis Imaging IRB
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92 Re: IRB 17-013902, Protocol Title: Congenital renal and urinary tract anomalies with associated pulmonary hypoplasia: A case series (2017)
1b PI: Natalie Rintoul
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19 Re: IRB 18-014829
91 Protocol Title: Delivery Room Management of Transposition of the Great Arteries (TGA) and Short Term Outcomes: A Descriptive Study (2018)
1b PI: Natalie Rintoul
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15 IRB 18-014850
2a Outcomes in ECMO treated neonates
2f Sara Demauro, Faith Kim Natalie Rintoul
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c6 A pilot feasibility and safety multi center trial of administering weight adjusted fixed dose of low molecular weight heparin (enoxaparin) to neonates with thrombosis (FiXET): study protocol
40 Leslie Raffini, MD; Natalie Rintoul, MD (co-investigator)
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2e Resuscitation of the Anomalous Neonate
17 Palliative Care
2e Perioperative Care of Newborns/Infants
3c Neonatal, Extracorporeal Membrane Oxygenation (ECMO)
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36 Melomeningocele care map (Heuer G, Flibotte J)
24 Lymphangioma sleep disorders
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d1 PreOp Guideline in the Fetal/SDU Section of the Guideline for Neonates with Critical Heart Defects Undergoing Intervention, CHOP Neonatal Critical Heart Defects (CHD) Cardiology QI Project, 2018-2019.
76 Notes: Educational and procedural material for the Special Delivery Unit at Children's Hospital of Philadelphia
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Description of Research Expertise
1e IRB 13-0107593d Protocol Name: Reintubation of post surgical neonates
17 PI: David Cohen
25 Study Contact Theodora Goebel
3b Primary Funder: Children's Anesthesiology Associate
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40 Fetal Tracheal Occlusion Congenital Diaphragmatic Hernia
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10 IRB 3779
24 Pulmonary Hypoplasia Program
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15 Milrinone IRB
19 Gastroschisis IRB
37 Maternal Progesterone/Fetal Neuroprotection IRB
21 Gastroschisis Imaging IRB
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92 Re: IRB 17-013902, Protocol Title: Congenital renal and urinary tract anomalies with associated pulmonary hypoplasia: A case series (2017)
1b PI: Natalie Rintoul
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19 Re: IRB 18-014829
91 Protocol Title: Delivery Room Management of Transposition of the Great Arteries (TGA) and Short Term Outcomes: A Descriptive Study (2018)
1b PI: Natalie Rintoul
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15 IRB 18-014850
2a Outcomes in ECMO treated neonates
2f Sara Demauro, Faith Kim Natalie Rintoul
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c6 A pilot feasibility and safety multi center trial of administering weight adjusted fixed dose of low molecular weight heparin (enoxaparin) to neonates with thrombosis (FiXET): study protocol
40 Leslie Raffini, MD; Natalie Rintoul, MD (co-investigator)
65
Description of Clinical Expertise
2d Care of the Surgical Neonate2e Resuscitation of the Anomalous Neonate
17 Palliative Care
2e Perioperative Care of Newborns/Infants
3c Neonatal, Extracorporeal Membrane Oxygenation (ECMO)
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36 Melomeningocele care map (Heuer G, Flibotte J)
24 Lymphangioma sleep disorders
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d1 PreOp Guideline in the Fetal/SDU Section of the Guideline for Neonates with Critical Heart Defects Undergoing Intervention, CHOP Neonatal Critical Heart Defects (CHD) Cardiology QI Project, 2018-2019.
76 Notes: Educational and procedural material for the Special Delivery Unit at Children's Hospital of Philadelphia
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173 Johng S, Radack J, DeMauro S, DiGeronimo R, Raffini L, Keene S, Mathew L, Connelly J, Hedrick H, Rintoul N: Bleeding and Thrombotic Events in Neonates Supported with VA ECMO: An Analysis of the ELSO Registry. 36th Annual ELSO Conference, Washington, DC September 2025 Notes: Platform Presentation.
20a Johng S, Rintoul N, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, DiGeronimo R on behalf of the CHNC ECMO Focus Group: Anticoagulation Practices for Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Poster Presentation.
177 Johng S, Radack J, DeMauro S, DiGeronimo R, Raffini L, Keene S, Mathew L, Connelly J, Hedrick H, Rintoul N: Bleeding and Thrombotic Events in Neonates Supported with VA ECMO: An Analysis of the ELSO Registry. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Platform Presentation.
1a2 Carr N, Fulmer M, Rumpel J, Makkar A, Mahmood B, Keene S, Rintoul N, Wild KT, Ashrafi A, Gogcu S, Rau C, Mankouski A, Pattison D, Best H, Boyden S, Mao R, Brunelli L: Efficacy of Universal Genome Sequencing in Infant Extracorporeal Membrane Oxygenation. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Poster Presentation.
226 Johng S, DiGeronimo R, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, Rintoul N on behalf of the CHNC ECMO Focus Group : Management of Bivalirudin for Primary Anticoagulation in Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Poster Presentation.
26b Johng S, Rintoul N, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, DiGeronimo R on behalf of the CHNC ECMO Focus Group: Anticoagulation Practices for Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. 41st Annual Children's National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure Symposium, Keystone, Colorado March 2025 Notes: Platform Presentation.
120 Moon, J, Yuan I, Oluwalade B, Rintoul N, Wild T, Chen S, Simpao A, Nelson O: “Short term outcomes in infants following primary ventriculoperitoneal (VP) shunt insertion” Society for Pediatric Anesthesiology (SPA-AAP), Orlando, FL 2 39 March 2025 Notes: Oral Presentation.
151 Arens J, Barlett R, Church J, Hirschl R, Mychaliska G, Rintoul N, Zwischenberger: "ECLS of the Future - Where Will We Be in 25 Years?" 41st Annual Children's National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure Symposium, Keystone, Colorado 39 March 2025 Notes: Oral Presentation.
286 Johng S, DiGeronimo R, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, Rintoul N on behalf of the CHNC ECMO Focus Group: Management of Bivalirudin for Primary Anticoagulation in Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. 41st Annual Children's National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure Symposium, Keystone, Colorado March 2025 Notes: Platform Presentation.
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Selected Publications
18e Mahmood H, Himebauch AS, Anton-Martin P, Baxelbaum K, Gaynor JW, Rintoul N, Brunetti MA: Neuromonitoring practices in pediatric extracorporeal membrane oxygenation patients: a survey of North American centers. Extracorporeal Life Support Organization Annual Conference, Washington, DC September 2025 Notes: Oral presentation.173 Johng S, Radack J, DeMauro S, DiGeronimo R, Raffini L, Keene S, Mathew L, Connelly J, Hedrick H, Rintoul N: Bleeding and Thrombotic Events in Neonates Supported with VA ECMO: An Analysis of the ELSO Registry. 36th Annual ELSO Conference, Washington, DC September 2025 Notes: Platform Presentation.
20a Johng S, Rintoul N, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, DiGeronimo R on behalf of the CHNC ECMO Focus Group: Anticoagulation Practices for Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Poster Presentation.
177 Johng S, Radack J, DeMauro S, DiGeronimo R, Raffini L, Keene S, Mathew L, Connelly J, Hedrick H, Rintoul N: Bleeding and Thrombotic Events in Neonates Supported with VA ECMO: An Analysis of the ELSO Registry. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Platform Presentation.
1a2 Carr N, Fulmer M, Rumpel J, Makkar A, Mahmood B, Keene S, Rintoul N, Wild KT, Ashrafi A, Gogcu S, Rau C, Mankouski A, Pattison D, Best H, Boyden S, Mao R, Brunelli L: Efficacy of Universal Genome Sequencing in Infant Extracorporeal Membrane Oxygenation. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Poster Presentation.
226 Johng S, DiGeronimo R, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, Rintoul N on behalf of the CHNC ECMO Focus Group : Management of Bivalirudin for Primary Anticoagulation in Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. Pediatric Academic Societies (PAS), Honolulu, Hawaii April 2025 Notes: Poster Presentation.
26b Johng S, Rintoul N, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, DiGeronimo R on behalf of the CHNC ECMO Focus Group: Anticoagulation Practices for Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. 41st Annual Children's National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure Symposium, Keystone, Colorado March 2025 Notes: Platform Presentation.
120 Moon, J, Yuan I, Oluwalade B, Rintoul N, Wild T, Chen S, Simpao A, Nelson O: “Short term outcomes in infants following primary ventriculoperitoneal (VP) shunt insertion” Society for Pediatric Anesthesiology (SPA-AAP), Orlando, FL 2 39 March 2025 Notes: Oral Presentation.
151 Arens J, Barlett R, Church J, Hirschl R, Mychaliska G, Rintoul N, Zwischenberger: "ECLS of the Future - Where Will We Be in 25 Years?" 41st Annual Children's National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure Symposium, Keystone, Colorado 39 March 2025 Notes: Oral Presentation.
286 Johng S, DiGeronimo R, Puia-Dumitrescu M, Handley S, Billimoria Z, Lichtsinn K, Yalon L, Connelly J, Carr N , Heyrend C, Miquel-Verges F, McCulley D, Yang M, Lusk L, Gowda S, Montgomery K, Rintoul N on behalf of the CHNC ECMO Focus Group: Management of Bivalirudin for Primary Anticoagulation in Neonatal Respiratory ECMO Therapy within the Children’s Hospitals Neonatal Consortium. 41st Annual Children's National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure Symposium, Keystone, Colorado March 2025 Notes: Platform Presentation.
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