David S Frankel, MD
Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Director, Cardiac Electrophysiology Laboratories, Hospital of the University of Pennsylvania
Department: Medicine
Contact information
Pavilion at the Hospital of the University of Pennsylvania
1 Convention Ave
2nd Floor, City Side
Philadelphia, PA 19104
1 Convention Ave
2nd Floor, City Side
Philadelphia, PA 19104
Office: 215-662-6801
Fax: 215-615-4350
Fax: 215-615-4350
Education:
BA (American History)
University of Pennsylvania, College of Arts and Sciences, Philadelphia, PA, 2000.
MD
University of Pennsylvania, School of Medicine, Philadelphia, PA, 2004.
Permanent linkBA (American History)
University of Pennsylvania, College of Arts and Sciences, Philadelphia, PA, 2000.
MD
University of Pennsylvania, School of Medicine, Philadelphia, PA, 2004.
Description of Clinical Expertise
ventricular tachycardiaatrial fibrillation
catheter ablation
supraventricular tachycardia
pacemakers (including leadless)
defibrillators (including subcutaneous)
cardiac resynchronization therapy
left atrial appendage closure (Watchman)
Description of Research Expertise
ventricular tachycardiaatrial fibrillation
catheter ablation
supraventricular tachycardia
pacing-induced cardiomyopathy
cardiac resynchronization therapy
Selected Publications
Pokorney SD, Nemeth H, Chiswell K, Albert C, Allyn N, Blanco R, Butler J, Calkins H, Elkind MSV, Fonarow GC, Fontaine JM, Frankel DS, Fermann GJ, Gale R, Kalscheur M, Kirchhof P, Koren A, Miller JB, Rashkin J, Russo AM, Rutan C, Steinberg BA, Piccini JP.: Design and rationale of a pragmatic randomized clinical trial of early dronedarone versus usual care to change and improve outcomes in persons with first-detected atrial fibrillation - the CHANGE AFIB study. Am Heart J Jan 2025.Liao TE, Xu L, Khoshknab MP, Peters CJ, Callans DJ, Marchlinski FE, Schaller RD, Frankel DS, Luebbert JJ, Guandalini GS, Nazarian S.: Techniques and outcomes of atrial fibrillation ablation in patients with persistent left superior vena cava. J Cardiovasc Electrophysiol Nov 2024.
Boyle TA, Reza N, Hyman M, Supple G, See VY, Marzolf A, Hornsby N, de Feria A, Wang T, Margulies KB, Owens AT, Frankel DS.: Atrial Fibrillation in Patients Receiving Mavacamten for Obstructive Hypertrophic Cardiomyopathy: Real-World Incidence, Management, and Outcomes. JACC Clin Electrophysiol Nov 2024.
Enriquez A, Frankel DS.: Sudden Cardiac Arrest and Abnormal ECG. JACC Case Rep 29: 102700, Nov 2024.
Hanumanthu BK, Wink J, Guandalini G, Marchlinski FE, Frankel DS, Markman TM.: Tumescent Local Anesthesia During Cardiac Implantable Electronic Device Implantation to Reduce Postoperative Pain. Circ Arrhythm Electrophysiol Nov 2024.
Chaumont C, Peyster E, Siontis KC, Muser D, Kapa S, Markman TM, Pathak RK, Oraii A, Rodriguez-Queralto O, Anselme F, Margulies KB, Marchlinski FE, Frankel DS.: Unipolar Voltage Mapping to Predict Recovery of Left Ventricular Ejection Fraction in Patients With Recent-Onset Nonischemic Cardiomyopathy. Circulation Nov 2024.
Peters CJ, Bode WD, Frankel DS, Garcia F, Supple GE, Giri JS, Kumareswaran R, Dixit S, Callans DJ, Marchlinski FE, Schaller RD.: Percutaneous balloon venoplasty for symptomatic lead-related venous stenosis. Heart Rhythm Oct 2024.
Torrado J, Sima A, Comstuck C, Kaszala K, Tan A, Koneru J, Frankel DS, Marchlinski F, Kowalski M, Sharma P, Gerstenfeld EP, Vaseghi M, Shivkumar K, Malhotra R, Morillo C, Ellenbogen KA, Huizar JF.: Prevalence of frequent premature ventricular contractions and left-ventricular systolic dysfunction in patients receiving Holter monitoring. J Cardiovasc Electrophysiol Oct 2024.
Yogasundaram H, Petzl AM, Raad M, Chaumont C, Guandalini GS, Kumareswaran R, Hyman MC, Schaller RD, Supple GE, Garcia FC, Nazarian S, Lin D, Riley MP, Dixit S, Callans DJ, Marchlinski FE, Frankel DS.: Combined catheter ablation of atrial fibrillation and premature ventricular complexes. Heart Rhythm Oct 2024.
Parks AL, Frankel DS, Kim DH, Ko D, Kramer DB, Lydston M, Fang MC, Shah SJ.: Management of atrial fibrillation in older adults. BMJ 386: e076246, Sep 2024.