David S Frankel, MD

faculty photo
Associate Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania
Director, Cardiac Electrophysiology Laboratories, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Pavilion at the Hospital of the University of Pennsylvania
1 Convention Ave
2nd Floor, City Side
Philadelphia, PA 19104
Office: 215-662-6801
Fax: 215-615-4350
Education:
BA (American History)
University of Pennsylvania, College of Arts and Sciences, Philadelphia, PA, 2000.
MD
University of Pennsylvania, School of Medicine, Philadelphia, PA, 2004.
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Description of Clinical Expertise

ventricular tachycardia
atrial fibrillation
catheter ablation
supraventricular tachycardia
pacemakers (including leadless)
defibrillators (including subcutaneous)
cardiac resynchronization therapy
left atrial appendage closure (Watchman)

Description of Research Expertise

ventricular tachycardia
atrial fibrillation
catheter ablation
supraventricular tachycardia
pacing-induced cardiomyopathy
cardiac resynchronization therapy

Selected Publications

Thind M, Arceluz MR, Lucena-Padros I, Kubala M, Mirwais M, Bode W, Cerantola M, Sugrue A, Van Niekerk C, Vigdor A, Patel NA, AlSalem AB, Zado ES, Kumareswaran R, Lin D, Arkles JS, Garcia FC, Guandalini GS, Markman TM, Riley MP, Deo R, Schaller RD, Nazarian S, Dixit S, Epstein AE, Supple GE, Frankel DS, Tschabrunn CM, Santangeli P, Callans DJ, Hyman MC, Marchlinski FE: Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm. JACC Clin Electrophysiol 9(11): 2275-2287, Nov 2023.

Arkles J, Markman T, Trevillian R, Yegya-Raman N, Garg L, Nazarian S, Santangeli P, Garcia F, Callans D, Frankel DS, Supple G, Lin D, Riley M, Kumaraeswaran R, Marchlinski F, Schaller R, Desjardins B, Chen H, Apinorasethkul O, Alonso-Basanta M, Diffenderfer E, Kim MM, Feigenberg S, Zou W, Marcel J, Cengel KA.: One-Year Outcomes Following Stereotactic Body Radiotherapy for Refractory Ventricular Tachycardia. Heart Rhythm Page: S1547-5271(23)02782-0, Oct 10 2023 Notes: online ahead of print.

Schaller RD, Hyman M, Supple GE, Santangeli P, Riley MP, Nazarian S, Arkles J, Garcia F, Lin D, Guandalini G, Kumareswaran R, Deo R, Bode W, Markman T, Epstein A, Callans DJ, Dixit S, Brozoski J, Marchlinski FE, Frankel DS: Defibrillation Testing of the Subcutaneous Implantable Cardioverter-Defibrillator at the time of Generator Replacement. Heart Rhythm Page: S1547-5271(23)02781-9, Oct 12 2023 Notes: online ahead of print.

Arceluz MR, Thind M, Hambach B, Garcia FC, Callans DJ, Guandalini GS, Frankel DS, Supple GE, Hyman M, Schaller RD, Nazarian S, Dixit S, Lin D, Marchlinski FE, Santangeli P.: Septal Substrate Ablation Guided by Delayed Transmural Conduction Times: A Novel Ablation Approach to Target Intramural Substrates. JACC Clin Electrophysiol 9(9): 1903-1913, Sep 2023.

Dhakal BP, Patel NA, Garg L, Frankel DS, Hyman MC, Guandalini GS, Supple GE, Nazarian S, Kumareswaran R, Riley MP, Santangeli P, Lin D, Callans DJ, Arkles J, Schaller RD, Tschabrunn CM, Zado ES, Marchlinski FE, Dixit S: Utility of Very High-Output Pacing to Identify VT Circuits in Patients Manifesting Traditionally Inexcitable Scar. JACC Clin Electrophysiol Page: S2405-500X(23)00628-X, Sep 13 2023 Notes: online ahead of print.

Markman TM, Peters C, Tate S, Guandalini GS, Hyman MC, Schaller RD, Supple GE, Riley MP, Garcia F, Nazarian S, Lin D, Dixit S, Epstein AE, Callans DJ, Marchlinski FE, Frankel DS: Accuracy of symptoms and pulse checking for detecting atrial fibrillation following catheter ablation. J Interv Card Electrophysiol Sep 12 2023 Notes: doi: 10.1007/s10840-023-01643-4. Online ahead of print.

Garg L, Moss J, Hyman MC, Arkles J, Callans DJ, Dixit S, Epstein AE, Frankel DS, Garcia FC, Kumareswaran R, Sharkoski T, Markman TM, Nazarian S, Riley MP, Santangeli P, Schaller RD, Supple GE, Marchlinski F, Deo R: Simultaneous comparison of patch versus multi-electrode cardiac monitoring for the detection of arrhythmias: The COMPARE study. Heart Rhythm 20(8): 1202-1203, Aug 2023.

Sugrue A, Ibrahim R, Lu M, Bhatia NK, Alkukhun L, Adewumi J, Schaller RD, Marchlinski FE, D'Souza B, Nazer B, Tzou W, Merchant FM, Frankel DS: Impact of Median Sternotomy on Safety and Efficacy of the Subcutaneous Implantable Cardioverter Defibrillator. Circ Arrhythm Electrophysiol 16(8): 468-474, Aug 2023.

Tan JL, Guandalini GS, Hyman MC, Arkles J, Santangeli P, Schaller RD, Garcia F, Supple G, Frankel DS, Nazarian S, Lin D, Callans D, Marchlinski FE, Markman TM: Substrate and arrhythmia characterization using the multi-electrode Optrell mapping catheter for ventricular arrhythmia ablation-a single-center experience. J Interv Card Electrophysiol Aug 2023 Notes: doi: 10.1007/s10840-023-01618-5. Online ahead of print.

Pipilas D, Frankel DS, Khurshid S: Pacing-induced cardiomyopathy after leadless pacemaker implant: It's all about location, location, location. J Cardiovasc Electrophysiol 34(6): 1427-1430, June 2023.

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Last updated: 01/22/2024
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