Sharyn I Katz, MD, MTR

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Associate Professor of Radiology at the Hospital of the University of Pennsylvania
Active Medical Staff, Penn-Presbyterian Medical Center, Department of Medical Imaging
Attending Medical Staff, Hospital of the University of Pennsylvania, Department of Radiology
Active Medical Staff, Pennsylvania Hospital, Department of Radiology
Active Medical Staff, Chester County Hospital, Department of Radiology
Active Medical Staff, Phoenixville Hospital
Department: Radiology

Contact information
Department of Radiology
Hospital of the University of Pennsylvania
One Silverstein Building
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-4000
B.A. (Chemistry and Biology)
College of the Holy Cross, 1992.
M.D. (Doctor of Medicine)
Rush University, Rush Medical College, 1999.
MTR (Translational Research)
University of Pennsylvania, 2011.
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Description of Research Expertise

Dr. Katz is thoracic radiologist and the Director of Research for the Division of Thoracic Radiology at the University of Pennsylvania Perelman School of Medicine. Her research is focused on devoted to thoracic oncology imaging for detection, staging, response evaluation, and treatment guidance for thoracic cancers.

Selected recent Publications (please follow Pubmed link below for additional publications)

Clinical impact of plasma-based genotyping for the delivery of personalized therapy in metastatic non-small cell lung cancer.
Aggarwal C, Thompson JC, Black TA, Katz SI, Fan R, Yee SS, Chien AL, Evans TL, Bauml JM, Alley JW, Ciunci CC, Berman A, Cohen RB, Lieberman DB, Majmundar KS, Savitch SL, Morrissette JJ, Hwang W, Elenitoba-Johnson KS, Langer CJ, Carpenter EL. JAMA Oncology. 2018

Radiologic Pseudoprogression during Anti-PD-1 Therapy for Advanced Non-
Small Cell Lung Cancer.
Katz SI, Hammer M, Bagley SJ, Aggarwal C, Bauml JM, Thompson JC, Nachiappan AC, Simone CB, Langer CJ. Journal of Thoracic Oncology. 2018

Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging.
Chen X, Yang Y, Katz S. Oncotarget. 2017

Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging.
Chen X, Yang Y, Berger I, Khalid U, Patel A, Cai J, Farwell MD, Langer C, Aggarwal C, Albelda SM, Katz SI. Oncotarget. 2017; 8(15):24213-24223.

Immunotherapy and radiation therapy for malignant pleural mesothelioma.
Alley EW, Katz SI, Cengel KA, Simone CB 2nd.
Translational lung cancer research. 2017; 6(2):212-219.

North American Multicenter Volumetric CT Study for Clinical Staging of Malignant Pleural Mesothelioma: Feasibility and Logistics of Setting Up a Quantitative Imaging Study.
Gill RR, Naidich DP, Mitchell A, Ginsberg M, Erasmus J, Armato SG 3rd, Straus C, Katz S, Patios D, Richards WG, Rusch VW.

A Multicenter Study of Volumetric Computed Tomography for Staging Malignant Pleural Mesothelioma.
Rusch VW, Gill R, Mitchell A, Naidich D, Rice DC, Pass HI, Kindler HL, De Perrot M, Friedberg J. Malignant Mesothelioma Volumetric CT Study Group. The Annals of thoracic surgery. 2016; 102(4):1059-66.

Description of Clinical Expertise

Dr. Katz is a thoracic radiologist with a clinical focus in lung cancer and malignant pleural mesothelioma. She is a member of the Abramson Cancer Center and Penn Mesothelioma and Pleural Program.
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Last updated: 05/16/2024
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