MacLean Nasrallah, MD PhD

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Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce St.
Philadelphia, PA 19104
AB (Mathematics)
Harvard University, 1997.
PhD (Neuroscience)
University of Pennsylvania, 2010.
University of Pennsylvania, 2012.
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Description of Clinical Expertise

molecular pathology of neuropathology

Description of Research Expertise

brain development
mouse models
in utero electroporation in mouse models
molecular biology

Selected Publications

Rathore S, Akbari H, Rozycki M, Abdullah KG, Nasrallah MP, Binder ZA, Davuluri RV, Lustig RA, Dahmane N, Bilello M, O'Rourke DM, Davatzikos C: Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1. Scientific Reports March 2018.

Wu J, Zou T, Bai HX, Li X, Zhang Z, Xiao B, Nasrallah M, Karakousis G, Cao Y, Zhang PJ, Yang L: Comparison of chemoradiotherapy with radiotherapy alone for "biopsy only" anaplastic astrocytoma Oncotarget 8(40): 69038-69046, Apr 2017 Notes: doi: 10.18632/oncotarget.17441. eCollection 2017 Sep 15.

Nabavizadeh SA, Pechersky D, Schmitt JE, Nasrallah M, Wolf R, Loevner L, Mamourian AC: Perilesional hyperintensity on T1-weighted images in intra-axial brain masses other than cavernous malformations. J Neuroimaging 5: 531-538, Sep 2017 Notes: First published: 18 January 2017. DOI: 10.1111/jon.12424.

Zeh R, Sheikh S, Xia L, Pierce J, Newton A, Predina J, Cho S, Nasrallah M, Singhal S, Dorsey J, Lee JYK: The second window ICG technique demonstrates a broad plateau period for near infrared fluorescence tumor contrast in glioblastoma. PLoS One 12(7): e0182034, Jul 2017 Notes: doi: 10.1371/journal.pone.0182034. eCollection 2017.

Nasrallah MP, Nasrallah IM, Prelack MS, Johnson MO, Lewis TB, Rubenstein M, Minturn JE, Desai A, Marcotte P, Santi M, Martinez-Lage M: 19-year-old male with headaches and a possible seizure. Brain Pathol 27(4): 557-558, Jul 2017.

O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV: A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma. Sci Transl Med 9: 399, Jul 2017.

Verma G, Mohan S, Nasrallah MP, Brem S, Lee JY, Chawla S, Wang S, Nagarajan R, Thomas MA, Poptani H: Non-invasive detection of 2-hydroxyglutarate in IDH-mutated gliomas using two-dimensional localized correlation spectroscopy (2D L-COSY) at 7 Tesla. J Transl Med 14(1): 274, Sep 2016.

Piazza MA, Ramayya AG, Geiger GA, Alonso-Basanta M, Nasrallah MP, Welch WC, Ozturk AK: Intramedullary recurrence of a thoracic meningioma-presentation of an unusual case and review of the literature. World Neurosurg 92: 588, Aug 2016 Notes: Case report and review.

Marsh ED, Nasrallah MP, Walsh C, Murray KA, Nicole Sunnen C, McCoy A, Golden JA: Developmental interneuron subtype deficits after targeted loss of Arx. BMC Neurosci 17(1): 35, Jun 2016.

Nasrallah MP, Pramick MR, Baloch ZW: Images in endocrine pathology: parasitic nodule of thyroid in neck of patient with family history of papillary thyroid carcinoma. Endocr Pathol 26(3): 273-5, Sep 2015 Notes: Case report.

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Last updated: 03/28/2018
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