Christopher P. Bonafide, MD, MSCE
Professor of Pediatrics (General Pediatrics) at the Children's Hospital of Philadelphia
Attending Physician, Division of General Pediatrics, Children's Hospital of Philadelphia
Core Faculty, Clinical Futures, a Center of Emphasis, Children's Hospital of Philadelphia Research Institute
Associate Member, Institute for Translational Medicine and Therapeutics, University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania
Core Faculty, Section of Clinical Informatics, Division of General Pediatrics, Children's Hospital of Philadelphia
Co-Director, Pediatric Hospital Epidemiology and Outcomes Research Training (PHEOT) T32 Program, Children's Hospital of Philadelphia
Core Faculty, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia
Research Director, Section of Hospital Medicine, Children's Hospital of Philadelphia
Director of Pediatric Implementation Research, Implementation Science Center, University of Pennsylvania
Associate Chief for Research Integration and Implementation, Division of General Pediatrics, Children's Hospital of Philadelphia
Associate Director for Implementation Science, Clinical Futures, a Center of Emphasis, Children's Hospital of Philadelphia Research Institute
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
3500 Civic Center Blvd
Philadelphia, PA 19104
3500 Civic Center Blvd
Philadelphia, PA 19104
Publications
Education
BA (Psychology)
Colby College, 2000.
MD
Pennsylvania State University College of Medicine, 2004.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2011.
Permanent linkBA (Psychology)
Colby College, 2000.
MD
Pennsylvania State University College of Medicine, 2004.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2011.
Description of Research Expertise
I am an implementation scientist focused on the pediatric hospital setting, with a particular interest in deimplementing overused and ineffective practices.Specific areas of focus include:
-Bronchiolitis and other lung diseases in children
-Patient Safety
-Clinical Communication
-Human Factors Engineering
-Physiologic Monitoring Systems
-Alarm and Alert Fatigue
Description of Clinical Expertise
Pediatric hospital medicineDescription of Other Expertise
Clinical informaticsSelected Publications
Kurtz J, Ellis M, Chang F, Lanza J, Rodrigo P, Dickens H, Roman M, Nguyen J, Simmons P, Jones J, Chainani S, Tenney-Soeiro R, Hart J, Bonafide C, Maletsky KD.: Increasing Rounds Participation for Caregivers Who Prefer a Language Other Than English. Hosp Pediatr Sep 2026.Luke MJ, Zhu Y, Wolk CB, Menko SG, Capriola D, Fuller K, Scribano PV, Bonafide CP, Vasan A.: Patient Portal Use and Care Utilization Among Hospitalized Children. Hosp Pediatr Aug 2026.
Kern-Goldberger AS, Faerber JA, Xiao R, Makeneni S, Albanowski K, Brent CR, Ruppel H, Halley TV, McQuistion KM, Schisterman EF, Beidas RS, Bonafide CP; for the Pediatric Research in Inpatient Settings (PRIS) Network: Association between clinician team structure and continuous pulse oximetry overuse among infants hospitalized with bronchiolitis: An Eliminating Monitor Overuse Trial substudy. J Hosp Med Aug 2026.
Wood JI, Stephens-Shields AJ, Xie D, Karavite DJ, Thayer JG, Grundmeier RW, Bonafide CP, Fiks AG, Bryant-Stephens TC, Huertas LM, Kenyon CC.: Single maintenance and reliever therapy strategies for Implementation and effectiveness trial (SMART & SIMPLE Trial): study protocol for a type II hybrid effectiveness-implementation cluster-randomized controlled trial. Contemp Clin Trials Commun 53: 101677, Jul 2026.
Kim SD, Dieterly H, Milstone A, Bonafide C, Elhaissouni N, Woods-Hill C; and the BrighT STAR LIBRA authorship group.: Blood Culture Practices in Pediatric Intensive Care Units to Inform a Diagnostic Stewardship Intervention. Hosp Pediatr Jul 2026.
Coogle L, Luo B, Khan A, Tomlinson AZ, L'Etoile N, Bonafide C, Ruppel H, DeChalus A: Overnight consult message volume and patterns to pediatric subspecialty fellows. J Hosp Med Jul 2026.
Hoyt BM, Thomas J, Tyler A, Temte E, McMahon M, Watson JD, Bonafide CP, Beidas RS, Xiao R, Schisterman EF, Tchou MJ; Pediatric Research in Inpatient Settings (PRIS) Network.: Nasogastric Hydration Utilization in Bronchiolitis, an EMO Trial Observational Substudy. Hosp Pediatr Jun 2026.
Dalton EM, Kern-Goldberger AS, Luke MJ, Krass P, Bonafide CP.: DAGs: Directed Acyclic Graphs for Drawing Assumptions and Guiding Causal Inference. Hosp Pediatr May 2026.
Luke MJ, Tenney-Soeiro R, Bonafide CP.: A Practical Guide for Group Peer Reviews to Train a New Generation of Reviewers and Scholars. Hosp Pediatr Feb 2026.
DeChalus A, Luo B, Khan A, Tomlinson AZ, Bonafide C, Ruppel H.: Characterization of Secure Message Use in a Children's Hospital. Hosp Pediatr Dec 2025.