Christopher P. Bonafide, MD, MSCE

faculty photo
Associate Professor of Pediatrics (General Pediatrics) at the Children's Hospital of Philadelphia
Attending Physician, Division of General Pediatrics, Children's Hospital of Philadelphia
Core Faculty, Clinical Futures, a Center of Emphasis, Children's Hospital of Philadelphia Research Institute
Associate Member, Institute for Translational Medicine and Therapeutics, University of Pennsylvania
Senior Fellow, Leonard Davis Institute of Health Economics, University of Pennsylvania
Core Faculty, Section of Clinical Informatics, Division of General Pediatrics, Children's Hospital of Philadelphia
Co-Director, Pediatric Hospital Epidemiology and Outcomes Research Training (PHEOT) T32 Program, Children's Hospital of Philadelphia
Core Faculty, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia
Research Director, Section of Hospital Medicine, Children's Hospital of Philadelphia
Director of Pediatric Implementation Research, Implementation Science Center, University of Pennsylvania
Associate Chief for Research Integration and Implementation, Division of General Pediatrics, Children's Hospital of Philadelphia
Associate Director for Implementation Science, Clinical Futures, a Center of Emphasis, Children's Hospital of Philadelphia Research Institute
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
3500 Civic Center Blvd
Philadelphia, PA 19104
Education:
BA (Psychology)
Colby College, 2000.
MD
Pennsylvania State University College of Medicine, 2004.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2011.
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Description of Research Expertise

I am an implementation scientist focused on the pediatric hospital setting, with a particular interest in deimplementing overused and ineffective practices.

Specific areas of focus include:
-Bronchiolitis and other lung diseases in children
-Patient Safety
-Clinical Communication
-Human Factors Engineering
-Physiologic Monitoring Systems
-Alarm and Alert Fatigue

Description of Clinical Expertise

Pediatric hospital medicine

Description of Other Expertise

Clinical informatics

Selected Publications

DeChalus A, Luo B, Khan A, Tomlinson AZ, Bonafide C, Ruppel H.: Characterization of Secure Message Use in a Children's Hospital. Hosp Pediatr Dec 2025.

Harris CD, Treasure JD, Albanowski K, Lipshaw MJ, Bonafide CP, Schroeder AR, Noelck M, Byrd C, Stalets EL, Cane R, Menachof K, Schondelmeyer AC.: The Appropriate Use of High-Flow Nasal Cannula in Bronchiolitis: A Delphi Approach. Hosp Pediatr Dec 2025.

Ullman AJ, Day T, Doyle R, Marsh N, Coyer FM, August D, Cole R, Keogh S, Kleidon TM, McBride CA, Takashima M, Xu HG, Kearney LN, Byrnes JM, Thomas C, Rahiman S, Ruppel H, Bonafide C, Gillespie B, Battley C, Gibson V, Souza S, Doubrovsky A, Davies MW, Curley MAQ, Ware RS.: Preventing InfusAte injuries throughout a Child's Hospitalization (PATCH): Study protocol for a type 1 hybrid randomized controlled trial. J Hosp Med Dec 2025.

Kurtz J, Simmons P, Jones JM, Nguyen J, Ellis M, Chang F, Hoehn B, Chang F, Dickens H, Rimes S, Roman M, Tenney-Soeiro R, Hart J, Bonafide CP, Maletsky KD.: Disparities in Family-Centered Rounds Participation by Caregiver's Preferred Language. Hosp Pediatr Dec 2025.

Mehta SD, Galligan M, Race J, Haines GR, Lutts MK, Bonafide CP, Sutton RM.: Emergency Transfers Are Associated With Increased Financial Charges. Hosp Pediatr Dec 2025.

Bonham B, Perez T, Bailey M, Barrowman N, Bonafide C, Boutin A, Buba M, Buchanan F, Carwana M, Chen BA, Constantin E, de Castris Garcia K, Del Giorgio F, Dionisopoulos Z, Fahim C, Forbes KL, Friedman JN, Gagnon JA, Gill PJ, Han M, Huynh N, Karaceper M, Klassen TP, Lahaie I, Li P, Moretti M, Mahant S, Manos S, Mekhici H, Novak C, Ostrow O, Quach C, Quet J, Sakran M, Seghal A, Shroeder AR, Turcot MA, Wahi G, Drouin O; Canadian Pediatric Inpatient Research Network (PIRN): Low-value care and variation in practice in the care of children hospitalized with bronchiolitis in Canada (CareBEST): Protocol for a multi-center prospective cohort study. J Hosp Med Nov 2025.

Wolk CB, O'Brien CS, Bonafide C, Beidas RS, Schisterman EF, Albanowski K, Brent C, Schondelmeyer AC: Caregiver experiences with deimplementation of continuous pulse oximetry monitoring for children hospitalized with bronchiolitis: A qualitative study. J Hosp Med Page: In press, Sep 2025.

Corson CL, Nembhard IM, Bonafide CP, Foglia EE, Lee HC, Handley SC: Acceptance and Implementation of Evidence-Based Practices in Delivery Room Resuscitation: A Qualitative Study. SSM Qual Res Health Page: 110746, Jul 2025 Notes: doi: 10.1016/j.resuscitation.2025.110746.

Warniment A, Hall M, Berry JG, Korn E, Griego E, Lu E, Steuart R, Bonafide C, Simon T, Tarchichi T, Shah SS, Thomson J.: Effects of airway clearance in hospitalized children with neurologic impairment. J Hosp Med 20(5): 479-484, May 2025.

Vasthare Shapiro A, Londoño Gentile T, Dickens H, Bonafide CP, Fieldston E.: Care Team Assistants as a Strategy to Reduce Physicians' Administrative Task Burden. Hosp Pediatr 15(1): e143-e147, Apr 2025.

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Last updated: 12/15/2025
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