Phillip B. Storm, M.D.

faculty photo
Professor of Neurosurgery at the Children's Hospital of Philadelphia
Attending Neurosurgeon, Children’s Hospital of Philadelphia
Chief of Neurosurgery, Children's Hospital of Philadelphia
Leslie Sutton Endowed Chair Holder, Children's Hospital of Philadelphia
Director of the Center for Data Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia
Co-Director Neuroscience Center, Children's Hospital of Philadelphia
Vice Chair of Clinical Affairs, Department of Surgery, Children's Hospital of Philadelphia
Department: Neurosurgery

Contact information
The Children's Hospital of Philadelphia
34th St & Civic Center Boulevard
Philadelphia, PA 19104
Office: (215) 590-2780
Fax: (215) 590-4809
Education
B.A. (Chemistry & Sociology)
Wake Forest University, 1990.
M.D.
Johns Hopkins University School of Medicine (AOA), 1996.
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Description of Research Expertise

Dr. Storm is a pediatric neurosurgeon-scientist and co-founder and Director of the Center for Data-Driven Discovery in Biomedicine, known as D3b. D3b is a disease-agnostic, age-agnostic, specialty-agnostic, and institution-agnostic discovery platform that integrates clinical, imaging, pathology, biospecimen, genomic, proteomic, and longitudinal outcome data to accelerate research, artificial intelligence, clinical trials, and precision medicine.

D3b supports national and international programs including the Children’s Brain Tumor Network, the NIH funded Gabriella Miller Kids First Data Resource Center, ARPA-H funded RADIANT and PCX, the NIH funded INCLUDE Data Coordinating Center, the Philadelphia Coalition for a Cure (PC4C), and CORSICA. Its scope extends beyond CHOP, beyond pediatrics, and beyond tumors, supporting research across the lifespan including adult and pediatric brain tumors, sinonasal cancer, epilepsy, structural birth defects, Down syndrome, autism, rare diseases, and other neurological and developmental conditions.

Dr. Storm’s research expertise includes open science, multimodal data integration, artificial intelligence, real-time clinical data analysis, external control cohorts, decentralized clinical trials, biomarker discovery, radiogenomics, precision surgery, and learning health systems. His work focuses on creating scalable infrastructure that connects every patient, biospecimen, image, and clinical outcome to discovery and improved care.

Description of Clinical Expertise

Dr. Storm specializes in complex pediatric neurosurgery, particularly tumors of the brain, spine, skull base, and craniocervical junction. His expertise includes endoscopic endonasal and minimally invasive skull base surgery, craniopharyngioma, intraventricular and brainstem tumors, spinal cord and vertebral tumors, complex cervical spine reconstruction, vascular malformations, and neuroendoscopy.

He has built nationally recognized programs in pediatric neuro-oncology, endoscopic skull base surgery, complex spine surgery, vascular neurosurgery, epilepsy surgery, and precision surgery. His clinical practice integrates advanced imaging, molecular profiling, intraoperative technology, multidisciplinary care, and longitudinal outcomes.

Description of Other Expertise

Dr. Storm is a transformational physician-executive and program builder with expertise in organizational growth, faculty development, philanthropy, clinical operations, institutional strategy, and the integration of clinical care, research, data science, and innovation.

As Chief of Neurosurgery at the Children’s Hospital of Philadelphia, he has built one of the nation’s largest, most clinically active, and most highly funded pediatric neurosurgery programs. He expanded the faculty, established nationally recognized clinical and research programs, developed multiple endowed chairs, substantially increased clinical volume and revenue, and created a multidisciplinary enterprise of clinicians, scientists, engineers, and research professionals.

His leadership model focuses on recruiting exceptional people and providing the culture, mentorship, infrastructure, and resources that allow them to develop independently successful programs. Benjamin Kennedy, MD, has built an epilepsy program supported by several million dollars in philanthropy, an endowed chair, and NIH funding. Adam Kundishora, MD, has secured nearly $1 million in research support and an NINDS R01 with a sixth-percentile score. Gregory Heuer, MD, holds an endowed chair and has attracted more than $1 million in philanthropy during the past two years.

Alex Tucker, MD, has developed two United States patents and one international patent, founded a company, and received multiple small-business research awards. He is building a cervical spine and Chiari program, and the Bobby Jones Chiari & Syringomyelia Foundation is transferring the operating center of its consortium to CHOP under his leadership. He also has three R-series NIH grant applications under review. Peter Madsen, MD, has secured foundation, philanthropic, and industry support for a brain tumor research program focused on CAR T-cell therapy and patient-derived organoid development.

The Center for Data-Driven Discovery in Biomedicine, known as D3b, is the clearest expression of Dr. Storm’s leadership model. D3b is not a conventional laboratory centered on one investigator, institution, age group, or disease. It is an enabling platform that helps investigators and programs generate data, secure federal funding and philanthropy, form industry partnerships, develop clinical trials, create new companies and technologies, and translate discoveries into patient care. Its infrastructure supports programs extending beyond CHOP, pediatrics, neurosurgery, and tumors, including epilepsy, Chiari malformation, structural neurological disorders, the Philadelphia Coalition for a Cure, and CORSICA.

Dr. Storm’s leadership philosophy, “Innovation Through Collaboration,” centers on recruiting and developing exceptional people, eliminating institutional silos, sharing infrastructure and opportunity, and building enduring programs that extend beyond a single investigator, division, institution, age group, or disease. His work provides the proven foundation for an institute-level enterprise in data-driven discovery capable of uniting clinical medicine, artificial intelligence, multi-omic science, engineering, clinical trials, philanthropy, entrepreneurship, and industry across an academic health system.

Selected Publications

Gabriel ED, Kumar NK, Senthil K, Hejazi-Garcia C, Wang C, Lacoul A, Mazandi V, Wannasarnmetha M, Bhatia A, Tucker AM, Storm PB, Flanders TM, Heuer GG, Kennedy BC, Kirschen M, Topjian A, Francoeur C, Yuan I, Kim CT, Kilbaugh TJ, Huh JW, Lang SS: Correlation of noninvasive near-infrared spectroscopy with outcomes in pediatric traumatic brain injury. J Neurosurg Pediatr June 2026.

Song JH, Baron J, Perez CC, Ramesh S, Minturn J, Desai KA, Shah AC, Belasco JM, Cole KA, Fisher MJ, Storm PB, Madsen PM, Kurtz G, Lustig RA, Hill-Kayser C, LaRiviere MJ.: Feasibility and Safety of High-Dose Proton Re-Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single-Institution Retrospective Study. Pediatr Blood Cancer May 2026.

Talati VM, Zhang K, Wei KX, Mitchell MB, Adappa ND, Kohanski MA, Douglas JE, Jackson C, Lee JYK, Storm PB, Lazor JW, Palmer JN.: Fascia-Fat-Fascia "Sandwich Graft" Decreases Postoperative Cerebrospinal Fluid Leak Rate for High-Flow Skull Base Defects. Int Forum Allergy Rhinol Apr 2026.

Sussman JH, Oldridge DA, Yu W, Chen CH, Zellmer AM, Rong J, Parvaresh-Rizi A, Thadi A, Yang A, Tumulty JS, Xiong B, Wu DW, Sun Y, Bandyopadhyay S, Xu J, Brosius S, Barkardottir UY, Seka I, Ahn KJ, Elghawy O, Baxter AE, Koptyra MP, Vanguri RS, McGrory S, Storm PB, Amankulor NM, Santi M, Viaene AN, Zhang N, De Raedt T, Cole K, Tan K.: A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma. Cell Rep Med Apr 2026.

Fathi Kazerooni A, Jiang Z, Gandhi D, Khalili N, Liu X, Tu W, Ware JB, Familiar AM, Vunnava B, Zapaishchykova A, McAllister AS, Sanchez-Montano M, Sheth N, Nandolia KK, Lai HA, Pavaine J, Prabhu SP, Haldar D, Varshochi S, Bagheri S, Anderson H, Haldar S, Khalili N, Gottipati A, Shaikh IS, Castellino E, Mangoli A, Gohil H, Maleki N, Low J, Hummel T, Packer RJ, Franson A, Storm PB, Bakas S, Calabrese E, Aboian M, de Blank P, Kann BH, Rood B, Resnick AC, Nabavizadeh A, Vossough A, Linguraru MG.: Multi-Institutional Annotated Multiparametric MRI Dataset of Pediatric High-Grade Gliomas. Radiol Artif Intell Apr 2026.

Maoz SL, Lee M, Fischer JL, Choby G, Hwang PH, Wang EW, Kuan EC, Adappa ND, Geltzeiler M, Getz AE, Humphreys IM, Le CH, Pinheiro-Neto CD, Chan EP, Roozdar P, Abuzeid WM, Chang EH, Jafari A, Kingdom TT, Kohanski MA, Lee JT, Lazor J, Nabavizadeh A, Nayak JV, Palmer JN, Patel ZM, Resnick AC, Smith TL, Snyderman CH, St John MA, Storm PB, Suh JD, Wang MB, Sim MS, Beswick DM.: Minimal Clinically Important Difference of the Sinonasal Outcome Test in Sinonasal Malignancy. Ann Otol Rhinol Laryngol Mar 2026.

Naqvi AS, Sullivan PJ, Corbett RJ, Sehgal P, Conkrite KL, Rathi KS, Ennis BM, Hayer KE, Zhang B, Brown MA, Miller DP, Sickler A, Kraya AA, Coleman KL, Dybas JM, Geng Z, Blackden C, Arif S, Chroni A, Lahiri A, Hollawell ML, Storm PB, Haydar D, Foster JB, Koptyra M, Madsen PJ, Diskin SJ, Thomas-Tikhonenko A, Resnick AC, Rokita JL.: Alternative splicing in pediatric central nervous system tumors highlights oncofetal candidate CLK1 exon 4. Neurooncol Pediatr 2: wuag009, Feb 2026.

Chrysochoou D, Gandhi DB, Adib S, Familiar AM, Vunnava B, Varshochi S, Khalili N, Khalili N, Ware JB, Tu W, Jain P, Anderson H, Haldar S, Storm PB, Franson A, Prados M, Kline C, Mueller S, Resnick A, Vossough A, Davatzikos C, Nabavizadeh A, Kazerooni AF.: AI-powered segmentation and prognosis with missing MRI in pediatric brain tumors. NPJ Precis Oncol Jan 2026.

Corbett RJ, Kaufman RS, McQuaid SW, Vaksman Z, Phul S, Brown MA, Mason JL, Waszak SM, Zhang B, Zhong C, Blauel E, Desai H, Hausler R, Naqvi AS, Daggett JM, Sickler A, Cresswell-Clay EC, Sullivan PJ, Chroni A, Geng Z, Gonzalez EM, Zhu Y, Heath AP, Li M, Storm PB, Resnick AC, Maxwell KN, Cole KA, Waanders AJ, Bornhorst M, MacFarland SP, Rokita JL, Diskin SJ.: Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors. Nat Commun Nov 2025.

Kazerooni AF, Familiar AM, Aboian M, Brüningk SC, Vossough A, Linguraru MG, Huang RY, Hargrave D, Peet AC, Resnick AC, Storm PB, Mirsky D, Yeom KW, Weller M, Prados M, Chang SM, Mueller S, Villanueva-Meyer JE, Bakas S, Fangusaro J, Kann BH, Nabavizadeh A; Response Assessment in Pediatric Neuro-Oncology (RAPNO) group.: Artificial Intelligence for Response Assessment in Pediatric Neuro-Oncology (AI-RAPNO), part 2: challenges, opportunities, and recommendations for clinical translation. Lancet Oncol Nov 2025.

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Last updated: 07/11/2026
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