Denis Hadjiliadis, MD, MHS, PhD

faculty photo
Paul F. Harron, Jr. Professor
Director, Adult Cystic Fibrosis Program, University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street
9031A Floor, West Gates Building
Philadelphia, PA 19104
Office: 215-662-4202
Fax: 215-614-0869
(Chemical Engineering (B.Eng; 2 years completed))
Faculty of Engineering, McGill University, Montreal, Canada, 1991.
MD (Doctor of Medicine Program)
Faculty of Medicine, University of Toronto, Canada, 1995.
MHS (Master’s of Health Sciences Program)
Duke University Medical Center, Durham, NC, 2001.
PhD (Ph.D in Medicine Program)
University of Ioannina, Ioannina, Greece, 2005.
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Description of Research Expertise

Cystic Fibrosis
Lung Transplantation
Bronchiolitis Obliterans
Database Analysis

Description of Clinical Expertise

Cystic Fibrosis
Lung Transplantation
CFTR-Related Disorder
Bronchiolitis Obliterans
Non-tuberculous mycobacteria
Palliative Care

Description of Other Expertise

Dr Hadjiliadis oversees one of the largest adult cystic fibrosis clinics in North America. He also has experience in the diagnosis and management of patients with bronchiectasis and CFTR-related disorder. In addition, he is a member of the Penn Lung Transplantation team and takes care of patients with end-stage lung disease requiring transplant. He is also a member Palliative Care team at the University of Pennsylvania

Multiple clinical trials in the above areas are available to patients at the University of Pennsylvania

Selected Publications

Nyirjesy, SC; Peleckis, AJ; Eiel, JN; Gallagher, K; Doliba, A; Tami, A; Flatt, AJ; De Leon, DD; Hadjiliadis, D; Sheikh, S; Stefanovski, D; Gallop, R; D'Alessio, DA; Rubenstein, RC; Kelly, A; Rickels, MR: Effects of GLP-1 and GIP on Islet Function in Glucose Intolerant, Pancreatic Insufficient Cystic Fibrosis. Diabetes July 2022.

Kelly, Andrea, Sheikh, Saba, Stefanovski, Darko, Peleckis C R N P, Amy J, Nyirjesy, Sarah C, Eiel, Jack N, Sidhaye, Aniket, Localio, Russell, Gallop, Robert, De Leon, Diva D, Hadjiliadis, Denis, Rubenstein, Ronald C, Rickels, Michael R: Randomized, Controlled Trial Of Sitagliptin And Islet Function In Cystic Fibrosis With Abnormal Glucose Tolerance. The Journal Of Clinical Endocrinology And Metabolism 106(9): 2617-2634, Aug 2021 Notes: epub before print, May 2021.

Kelly A, Sheikh S, Stefanovski D, Peleckis AJ, Nyirjesy SC, Eiel JN, Sidhaye A, Localio R, Gallop R, De Leon DD, Hadjiliadis D, Rubenstein RC, Rickels MR.: Effect of Sitagliptin on Islet Function in Pancreatic Insufficient Cystic Fibrosis With Abnormal Glucose Tolerance. J Clin Endocrinol Metab. 106(9): 2617-2634, Aug 2021.

Roe, Andrea H; Yapalater, Sophia; Hadjiliadis, Denis: Electronic health nudges to improve reproductive health care for women with cystic fibrosis. Journal of Cystic Fibrosis 20(3): 397-398, May 2021 Notes: ePub ahead of print, November 2020.

Hajizadeh N, Zhang M, Akerman M, Kohn N, Mathew A, Hadjiliadis D, Wang J, Lesser ML.: Survival models to support shared decision-making about advance care planning for people with advanced stage cystic fibrosis. BMJ Open Respir Res. 8(1): E000794, May 2021.

JE Douglas, AM Civantos, TB Locke, AM Sweis, D Hadjiliadis, G Hong, D Dorgan, MA. Kohanski, JN Palmer, ND Adappa: Impact of Novel CFTR Modulator on Sinonasal Quality of Life in Adult Patients with Cystic Fibrosis. International Forum of Allergy & Rhinology 11(2): 201-203, Feb 2021 Notes: Epub ahead of print, October 2020.

Zysman-Colman, Zofia N., Kilberg, Marissa J., Harrison, Victor S., Chesi, Alessandra, Grant, Struan F. A., Mitchell, Jonathan, Sheikh, Saba, Hadjiliadis, Denis, Rickels, Michael R., Rubenstein, Ronald C., Kelly, Andrea : Genetic potential and height velocity during childhood and adolescence do not fully account for shorter stature in cystic fibrosis. Pediatric Research 89(3): 653-659, Feb 2021 Notes: Epub ahead of print, May 2020.

Courtwright, Andrew M., Kamoun, Malek, Diamond, Joshua M., Kearns, Jane, Ahya, Vivek N., Christie, Jason D., Clausen, Emily, Hadjiliadis, Denis, Patel, Namrata, Salgado, Juan C., Cevasco, Marisa, Cantu, Edward E., Crespo, Maria M., Bermudez, Christian A.: Lung transplantation outcomes after crossing low-level donor specific antibodies without planned augmented immunosuppression. Clinical Transplantation 2021.

Stephen MJ; Chowdhury J; Tejada LA; Zanni R; Hadjiliadis D.: Use of medical marijuana in cystic fibrosis patients. BMC Complementary Medicine and Therapies 20(1): Epub ahead of print, October 2020.

Kilberg, Marissa J, Harris, Clea, Sheikh, Saba, Stefanovski, Darko, Cuchel, Marina, Kubrak, Christina, Hadjiliadis, Denis, Rubenstein, Ronald C, Rickels, Michael R, Kelly, Andrea: Hypoglycemia and Islet Dysfunction following Oral Glucose Tolerance Testing in Pancreatic Insufficient Cystic Fibrosis. The Journal Of Clinical Endocrinology And Metabolism 4(1): 2179-3189, Jul 2020.

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Last updated: 09/10/2022
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