Denis Hadjiliadis, MD, MHS, PhD

faculty photo
Paul F. Harron, Jr. Professor
Director, Adult Cystic Fibrosis Program, University of Pennsylvania
Co-Director, Cystic Fibrosis Program, Perelman School of Medicine, University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street
9031A Floor, West Gates Building
Philadelphia, PA 19104
Office: 215-662-4202
Fax: 215-614-0869
(Chemical Engineering (B.Eng; 2 years completed))
Faculty of Engineering, McGill University, Montreal, Canada, 1991.
MD (Doctor of Medicine Program)
Faculty of Medicine, University of Toronto, Canada, 1995.
MHS (Master’s of Health Sciences Program)
Duke University Medical Center, Durham, NC, 2001.
PhD (Ph.D in Medicine Program)
University of Ioannina, Ioannina, Greece, 2005.
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Description of Research Expertise

Cystic Fibrosis
Lung Transplantation
Bronchiolitis Obliterans
Database Analysis

Description of Clinical Expertise

Cystic Fibrosis
Lung Transplantation
CFTR-Related Disorder
Bronchiolitis Obliterans
Non-tuberculous mycobacteria
Palliative Care

Description of Other Expertise

Dr Hadjiliadis oversees one of the largest adult cystic fibrosis clinics in North America. He also has experience in the diagnosis and management of patients with bronchiectasis and CFTR-related disorder. In addition, he is a member of the Penn Lung Transplantation team and takes care of patients with end-stage lung disease requiring transplant. He is also a member Palliative Care team at the University of Pennsylvania

Multiple clinical trials in the above areas are available to patients at the University of Pennsylvania

Selected Publications

Peng G; Taylor-Cousar JL; Lee M; Keller A; West NE; Kazmerski TM; Goralski JL; Aitken ML; Roe AH; Hadjiliadis D; Uluer A; Flume PA; Mody S; Bray LA; Jain R: Association between unplanned pregnancies and maternal exacerbations in cystic fibrosis. J Cyst Fibros. 22(5):796-803, 2023 Sep. 2023.

Basile, Melissa J. Dhingra, Lara DiFiglia, Stephanie Polo, Jennifer Portenoy, Russell Wang, Janice Walker, Patricia Middour-Oxler, Brandi Linnemann, Rachel W. Kier, Catherine Friedman, Deborah Berdella, Maria Abdullah, Robert Yonker, Lael M. Markovitz, Martha Hadjiliadis, Denis Shiffman, Melissa Fischer, Francine Pollinger, Sophie Hardcastle, Margot Chaudhary, Nivedita Georgiopoulos, Anna M.: Development of a Cystic Fibrosis Primary Palliative Care Intervention: Qualitative Analysis of Patient and Family Caregiver Preferences. JOURNAL OF PATIENT EXPERIENCE 2023.

Flatt, Anneliese J Sheikh, Saba Peleckis, Amy J Alvarado, Paola Hadjiliadis, Denis Stefanovski, Darko Gallop, Robert J Rubenstein, Ronald C Kelly, Andrea Rickels, Michael R: Preservation of beta-cell function in pancreatic insufficient cystic fibrosis with highly effective CFTR modulator therapy. The Journal of clinical endocrinology and metabolism -Jul-28 2023.

O'Dea AL; Feng R; Glaser LJ; Kubrak C; Rubenstein RC; Dorgan DJ; Hadjiliadis D; Kawut SM; Hong G: The Clinical Association between Aspergillus fumigatus and Respiratory Outcomes in Adolescents and Adults with Cystic Fibrosis. Annals of the American Thoracic Society. 20(7):984-992, 2023 07. 2023.

Hong G; Daniel SG; Lee JJ; Bittinger K; Glaser L; Mattei LM; Dorgan DJ; Hadjiliadis D; Kawut SM; Collman RG: Distinct community structures of the fungal microbiome and respiratory health in adults with cystic fibrosis. J Cyst Fibros. 22(4):636-643, 2023 07. 2023.

Kazmerski TM; Stransky OM; Lavage DR; Taylor-Cousar JL; Sawicki GS; Ladores SL; Godfrey EM; Aitken ML; Fields A; Sufian S; Jain M; Barto TL; Billings J; Hadjiliadis D; Jain R: Sexual and reproductive health experiences and care of adult women with cystic fibrosis. Journal of Cystic Fibrosis. 22(2):223-233, 2023 03. 2023.

Roe AH; Koelper N; McAllister A; Barnhart KT; Schreiber CA; Hadjiliadis D: Cervical mucus quality in females with and without cystic fibrosis. J Cyst Fibros. 22(5):804-805, 2023 Sep. 2023.

Nyirjesy, SC; Peleckis, AJ; Eiel, JN; Gallagher, K; Doliba, A; Tami, A; Flatt, AJ; De Leon, DD; Hadjiliadis, D; Sheikh, S; Stefanovski, D; Gallop, R; D'Alessio, DA; Rubenstein, RC; Kelly, A; Rickels, MR: Effects of GLP-1 and GIP on Islet Function in Glucose Intolerant, Pancreatic Insufficient Cystic Fibrosis. Diabetes July 2022.

Lee IK; Jacome DA; Cho JK; Tu V; Young AJ; Dominguez T; Northrup JD; Etersque JM; Lee HS; Ruff A; Aklilu O; Bittinger K; Glaser LJ; Dorgan D; Hadjiliadis D; Kohli RM; Mach RH; Mankoff DA; Doot RK; Sellmyer MA: Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim. Journal of Clinical Investigation. 132(18), 2022 09 15. 2022.

Kelly, Andrea, Sheikh, Saba, Stefanovski, Darko, Peleckis C R N P, Amy J, Nyirjesy, Sarah C, Eiel, Jack N, Sidhaye, Aniket, Localio, Russell, Gallop, Robert, De Leon, Diva D, Hadjiliadis, Denis, Rubenstein, Ronald C, Rickels, Michael R: Randomized, Controlled Trial Of Sitagliptin And Islet Function In Cystic Fibrosis With Abnormal Glucose Tolerance. The Journal Of Clinical Endocrinology And Metabolism 106(9): 2617-2634, Aug 2021 Notes: epub before print, May 2021.

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Last updated: 12/07/2023
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