Stephan Kadauke, M.D., Ph.D.
Assistant Professor of Clinical Pathology and Laboratory Medicine
Attending Physician, Division of Transfusion Medicine, Children's Hospital of Philadelphia
Faculty Member, Division of Pathology Informatics, Children's Hospital of Philadelphia
Faculty Member, Department of Biomedical Health Informatics
Medical Director, Cell and Gene Therapy Informatics, Children's Hospital of Philadelphia
Associate Director, Cell and Gene Therapy Laboratory, Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine
Contact information
Children's Hospital of Philadelphia
CTRB, Third Floor, Room 3016
3501 Civic Center Blvd
Philadelphia, PA 19104
CTRB, Third Floor, Room 3016
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-616-9737
Publications
Links
Search PubMed for articles
CHOP Cell and Gene Therapy Laboratory
Stephan Kadauke's LinkedIn
CHOP Cell and Gene Therapy Informatics Blog
Search PubMed for articles
CHOP Cell and Gene Therapy Laboratory
Stephan Kadauke's LinkedIn
CHOP Cell and Gene Therapy Informatics Blog
Education:
BA (Biochemistry, summa cum laude)
Columbia University, 2005.
Ph.D. (Cell and Molecular Biology)
Perelman School of Medicine at the University of Pennsylvania, 2012.
M.D.
Perelman School of Medicine at the University of Pennsylvania, 2014.
Permanent linkBA (Biochemistry, summa cum laude)
Columbia University, 2005.
Ph.D. (Cell and Molecular Biology)
Perelman School of Medicine at the University of Pennsylvania, 2012.
M.D.
Perelman School of Medicine at the University of Pennsylvania, 2014.
Description of Clinical Expertise
Cellular therapy, cGMP, stem cells, bone marrow transplant, chimeric antigen receptor, CAR-T cells, virus-specific cytotoxic T lymphocytes, T/B cell depletion, cell manufacturing, graft manipulation, CliniMACS Prodigy, transfusion medicine, apheresis, red blood cell exchange, plasma exchange, thalassemia, sickle cell disease, thrombosis and hemostasis, coagulation, utilization management, laboratory information systems, healthcare analytics, clinical informatics, pathology informatics, datamart, enterprise data warehouseDescription of Research Expertise
Reproducible research, tidyverse, R, RStudio, R Markdown, Quarto, clinical data science, machine learning, tidymodels, GitHub, gene therapy, erythropoiesis, epigenetics, chromatin, CAR-T cells, immunotherapy, virus-specific cytotoxic T lymphocytes, GMP manufacturingSelected Publications
Myers RMM, Devine K, Li Y, Lawrence S, Leahy AB, Liu H, Vernau L, Callahan C, Baniewicz D, Kadauke S, McGuire R, Wertheim GB, Kulikovskaya I, Gonzalez VE, Fraietta JA, DiNofia AM, Hunger SP, Rheingold SR, Aplenc R, June CH, Grupp SA, Wray L, Maude SL: Reinfusion of CD19 CAR T Cells for Relapse Prevention and Treatment in Children with Acute Lymphoblastic Leukemia. Blood Advances February 2024.Gibson NM, Elgarten CW, Oved JH, Wray L, Freedman JL, Wang Y, Kadauke S, Hankins P, Nicholas P, Worster E, Kwiatkowski JL, Grupp SA, Bunin NJ, Olson TS: Outcomes of Unrelated Partial T Cell Depleted Stem Cell Transplantation for Patients with Hemoglobinopathies. Transplantation and Cellular Therapy 30(2): S301-S302, February 2024 Notes: Poster Presentation at ASTCT 2024, San Antonio, TX.
Hanna R, Porter E, Romero S, Wildenhain P, Beasley W, Kadauke S: REDCapTidieR: Extracting complex REDCap databases into tidy tables. Journal of Open Source Software February 2024.
Elgarten CW, Heidemann S, Freedman JL, Grupp SA, Hankins P, Kadauke S, Li Y, McGlynn B, Olson TS, Wang Y, Wray L, Wang L, Seif AE, Bunin NJ: Pilot Study of Unrelated Donor (URD) Peripheral Stem Cell Transplant (PSCT) with CD45RA-Depleted Addback Following TCRab/CD19 Depletion in Pediatric Patients with Hematologic Malignancies. Transplantation and Cellular Therapy 30(2): S9-S10, February 2024 Notes: Oral Presentation at ASTCT 2024, San Antonio, TX.
McClory SE, Elgarten CW, Quijano KN, Wohlschlaeger A, Hankins P, Wang L, Wang Y, Kadauke S, Monos D, Olson TS, Grupp SA, Ochfeld E, Heimall JR, Bunin NJ: Unrelated and Haploidentical Peripheral Stem Cell Transplant with Tcrαβ/CD19 Depletion for the Treatment of Pediatric Patients with Inborn Errors of Immunity. Transplantation and Cellular Therapy 30(2): S68, February 2024 Notes: Oral Presentation at ASTCT 2024, San Antonio, TX.
Devassy R, Collier V, Hankins P, Hanna RS, Porter E, Peters AJ, Grupp SA, Kadauke S: Rapid Onboarding of FACT-Compliant Electronic Record Systems. Transplantation and Cellular Therapy 30(2): S442, February 2024 Notes: Poster presentation at ASTCT 2024, San Antonio, TX.
Ingeno L, Thompson A, Grupp SA, Kwiatkowski J, Kadauke S: First Two Gene Therapies for Sickle Cell Disease Supported by CHOP Clinical Research. CHOP Cornerstone Blog January 2024 Notes: https://www.research.chop.edu/cornerstone-blog/first-two-gene-therapies-for-sickle-cell-disease-supported-by-chop-clinical-research.
Scott M, Grupp SA, Kadauke S: How Gene Therapy is Offering Hope -- Once Again. The Pulse (NPR/WHYY) November 2023 Notes: https://www.npr.org/2023/11/24/1200586452/the-pulse-catchup-draft-11-24-2023.
Scott M, Grupp SA, Kadauke S: CHOP’s on-site production could lower high cost of gene therapies. WHYY November 2023 Notes: https://whyy.org/segments/chops-on-site-production-could-lower-high-cost-of-gene-therapies/
Macdonald G, Kadauke S: Increasing Access to Cell Therapies. Genetic Engineering & Biotechnology News October 2023 Notes: https://www.genengnews.com/topics/bioprocessing/bedside-gmp-in-a-box-to-increase-cell-therapy-access/