Stephan Kadauke, M.D., Ph.D.
Associate Professor of Clinical Pathology and Laboratory Medicine
Attending Physician, Division of Transfusion Medicine, Children's Hospital of Philadelphia
Faculty Member, Division of Pathology Informatics, Children's Hospital of Philadelphia
Faculty Member, Department of Biomedical Health Informatics
Medical Director, Cell and Gene Therapy Informatics, Children's Hospital of Philadelphia
Associate Director, Cell Based Therapy Laboratory, Children's Hospital of Philadelphia
Department: Pathology and Laboratory Medicine
Contact information
Children's Hospital of Philadelphia
CTRB, Fourth Floor, Room 4022
3501 Civic Center Blvd
Philadelphia, PA 19104
CTRB, Fourth Floor, Room 4022
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-616-9737
Publications
Links
Search PubMed for articles
CHOP Cell and Gene Therapy Informatics Blog
CHOP Cell and Gene Therapy Laboratory
Stephan Kadauke's LinkedIn
Search PubMed for articles
CHOP Cell and Gene Therapy Informatics Blog
CHOP Cell and Gene Therapy Laboratory
Stephan Kadauke's LinkedIn
Education:
BA (Biochemistry, summa cum laude)
Columbia University, 2005.
Ph.D. (Cell and Molecular Biology)
Perelman School of Medicine at the University of Pennsylvania, 2012.
M.D.
Perelman School of Medicine at the University of Pennsylvania, 2014.
Permanent linkBA (Biochemistry, summa cum laude)
Columbia University, 2005.
Ph.D. (Cell and Molecular Biology)
Perelman School of Medicine at the University of Pennsylvania, 2012.
M.D.
Perelman School of Medicine at the University of Pennsylvania, 2014.
Description of Clinical Expertise
Cellular therapy, cGMP, stem cells, bone marrow transplant, chimeric antigen receptor, CAR-T cells, virus-specific cytotoxic T lymphocytes, T/B cell depletion, cell manufacturing, graft manipulation, CliniMACS Prodigy, transfusion medicine, apheresis, red blood cell exchange, plasma exchange, thalassemia, sickle cell disease, thrombosis and hemostasis, coagulation, utilization management, laboratory information systems, healthcare analytics, clinical informatics, pathology informatics, datamart, enterprise data warehouseDescription of Research Expertise
Reproducible research, tidyverse, R, RStudio, R Markdown, Quarto, clinical data science, machine learning, tidymodels, GitHub, gene therapy, erythropoiesis, epigenetics, chromatin, CAR-T cells, immunotherapy, virus-specific cytotoxic T lymphocytes, GMP manufacturingSelected Publications
Gibson N, Al Riyami A, Peedin A, Kadauke S, Grupp S, Olson T, Wang Y: Challenging immunophenotyping of sickle cell patients adversely affects gene therapy product manufacturing – case reports. Cytotherapy May 2025 Notes: Platform presentation at ISCT 2025, New Orleans, LA.Devassy R, Peters AJ, Porter E, Hanna RS, Atkinson M, Vernau L, Machietto R, Giacobbe NJ, Wilson BE Jr, Phillips CA, Blythe A, Phillips J, Potter J, Gray K, Molitoris K, Precourt M, Collier V, Hankins P, Grupp SA, Olson TS, Kadauke S: Implementing the Epic Cell Therapy Module: Lessons from a Comprehensive Digital Transformation. Transplantation and Cellular Therapy 31(2): S91, February 2025 Notes: Platform presentation at ASTCT 2025, Honolulu, HI.
Porter E, Grupp SA, Hanna R, Olson TS, Phillips C, Kadauke S: Predictive Modeling for Bone Marrow Transplant Inpatient Census: A 15- to 60-Day Forecasting Approach. Transplantation and Cellular Therapy 31(2): S526-S527, February 2025 Notes: Poster presentation at ASTCT 2025, Honolulu, HI.
Frangoul H, Wang Y, McManus M, Kadauke S, Grupp SA, Evans M: Unmet Need in Stem Cell Mobilization for Gene Therapy in Patients with Sickle Cell Disease (SCD): A Multicenter Review. Transplantation and Cellular Therapy 31(2): S255, February 2025 Notes: Poster presentation at ASTCT 2025.
Burke R, Atkinson M, Choudhari SS, Collier V, Giacobbe N, Gonnella K, Gray K, Kadauke S, Machietto R, Molitoris K, Olson TS, Phillips J, Potter J, Roth E, Smith K: Cellular Therapy Infusion Flowsheets: Epic Integration. Transplantation and Cellular Therapy 31(2): S462-S463, February 2025 Notes: Poster presentation at ASTCT 2025 in Honolulu, HI.
Lescoat A, Ghosh M, Kadauke S, Khanna D: Innovative cell therapies for systemic sclerosis: available evidence and new perspectives. Expert Review of Clinical Immunology 21(1): 29-43, September 2024.
Wyatt KD, Alexander N, Hills GD, Liang WH, Kadauke S, Volchenboum SL, Mian A, Phillips CA: Making sense of artificial intelligence and large language models—including ChatGPT—in pediatric hematology/oncology. Pediatric Blood & Cancer 71(9): e31143, September 2024.
Kadauke S: Streamlining cell and gene therapy supply chains: using semi-automation and AI for cost reduction. Cell & Gene Therapy Insights 10(7): 929-933, July 2024.
Myers RMM, Devine K, Li Y, Lawrence S, Leahy AB, Liu H, Vernau L, Callahan C, Baniewicz D, Kadauke S, McGuire R, Wertheim GB, Kulikovskaya I, Gonzalez VE, Fraietta JA, DiNofia AM, Hunger SP, Rheingold SR, Aplenc R, June CH, Grupp SA, Wray L, Maude SL: Reinfusion of CD19 CAR T Cells for Relapse Prevention and Treatment in Children with Acute Lymphoblastic Leukemia. Blood Advances 8(9): 2182-2192, May 2024.
McClory SE, Elgarten CW, Quijano KN, Wohlschlaeger A, Hankins P, Wang L, Wang Y, Kadauke S, Monos D, Olson TS, Grupp SA, Ochfeld E, Heimall JR, Bunin NJ: Unrelated and Haploidentical Peripheral Stem Cell Transplant with Tcrαβ/CD19 Depletion for the Treatment of Pediatric Patients with Inborn Errors of Immunity. Transplantation and Cellular Therapy 30(2): S68, February 2024 Notes: Oral Presentation at ASTCT 2024, San Antonio, TX.