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Frances S. Shofer, PhD

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Adjunct Professor of Emergency Medicine
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Director of Epidemiology & Biostatistics, Department of Emergency Medicine 34 University of Pennsylvania School of Medicine
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Department: Emergency Medicine
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46 Contact information
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Department of Emergency Medicine
22 University of Pennsylvania
25 Ground Floor, Ravdin Building
3a 3400 Spruce Street
Philadelphia, PA 19104-4283
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32 Fax: 215-573-2701
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18 Publications
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13 Education:
21 7 BA 19 (Biochemistry) c
33 University of Pennsylvania, 1977.
21 8 PhD 19 (Epidemiology) c
33 University of Pennsylvania, 1983.
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Selected Publications

100 Killeen D, Shofer F, Panebianco N, Baraniecki-Zwil G, Kramer J.: A Retrospective Analysis of Soft Tissue Point-of-Care Ultrasound (POCUS) in Primary Care. J Am Board Fam Med Jan 2026.

149 Batson I, Ihenatu C, Shofer F, Magda M, Abboud ME, Conlon L, Tsao S, Mamtani M.: Simulation Curriculum Improves Emergency Medicine Resident Preparedness for the New American Board of Emergency Medicine Certifying Exam. West J Emerg Med 27: 39-43, Jan 2026.

11c Wang H, Tian Z, Shofer FS, Qin L, Zhang Y.: Modest Effects of Age on Inflammatory Markers and Histological Features in the Murine Intervertebral Disc Injury Model. Am J Phys Med Rehabil 104: 1127-1132, Dec 2025.

187 Greenwood JC, Ratnayake C, Shabbir M, Opitz S, Jang DH, Choi WJ, Panebianco NL, Shofer FS, Augoustides JGT, Bakker J, Wald JW, Abella BS.: Timing of inotropic support is associated with mortality in patients with acute decompensated heart failure-associated cardiogenic shock. Intensive Care Med Exp 13: 111, Oct 2025.

18e Abramoff B, Dillingham T, Rybicki AK, Shofer F, McGinley E, Verma SS, Kuns MC, Barry JT, Pezzin LE.: Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program to Improve the Functioning of Persons Suffering from Post-acute Sequelae of SARS-CoV-2 infection (PASC): A Randomized Controlled Trial. Res Sq Aug 2025.

13c Tian Z, Chen K, Shofer FS, Chenna SS, Sandroni DZ, Qin L, Zhang Y.: TNFAIP8/TIPE2 inactivation modulates extracellular matrix organization gene expression and preserves the intervertebral disc structure in mice. Genes Dis 13: 101835, Aug 2025.

17e Agarwal AK, Ebert JP, Xiong R, Ali ZS, Lee D, Shofer F, Gitelman Y, Do D, Spencer EA, Grenader EM, Li F, Harhay MO, Delgado MK.: Peer and Patient Feedback to Increase Adherence to Postoperative Opioid Prescribing Guidelines: A Stepped-Wedge Cluster Randomized Clinical Trial. JAMA Surg 160: 866-874, Aug 2025.

179 Nguemeni Tiako MJ, Engel-Rebitzer E, Friedman A, Shofer F, Dolan A, Hess EP, Perrone J, Schapira MM, Meisel ZF.: Racial Disparities in Unmet Pain Treatment Preference, Pain Treatment Satisfaction and Subsequent Opioid Misuse: A Secondary Analysis of a National Multisite RCT. J Gen Intern Med Jun 2025.

112 Kao SH, Stumpf KG, Gaudio HA, Greenwood JC, Shin SS, Shofer FS, Jang DH.: The application of cell-free DNA methylation patterns in critical illnesses: A protocol paper. PLoS One 20: e0321626, May 2025.

197 Kramer JA, Shepherd C, Hess-Homeier D, Ochroch J, Mehta S, Baraniecki-Zwil G, Shofer FS, Elkassabany N, Hussain S, Panebianco N.: New Kids on the Block: Development and Assessment of a Multispecialty Fascia Iliaca Block Protocol and Training Program for Geriatric Hip Fracture in the Emergency Department. Cureus 17: e80560, Mar 2025.

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