John T. Farrar, M.D., Ph.D.

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Professor of Epidemiology in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Member, University of Pennsylvania Cancer Center, Philadelphia, PA
Clinical Associate, Department of Neurology, University of Pennsylvania, Philadelphia PA
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA
Co-Director, Biostatistics Analysis Center, Biostatistical and Epidemiology Consulting Center, Center for Clinical Epidemiology and Biostatistics
Co-Director, Master of Science in Clinical Epidemiology Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
Department: Biostatistics and Epidemiology

Contact information
Room 816, Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
Office: 215-898-5802
Fax: 215-573-5315
ScB. (Biology, Computer Science minor)
Brown University, 1976.
The University of Rochester School of Medicine, 1981.
M.S.C.E. (Center for Clinical Epidemiology and Biostatistics)
The University of Pennsylvania, 2000.
Ph.D. (Graduate Group - Biostatistics and Epidemiology)
The University of Pennsylvania School of Medicine, 2004.
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Description of Research Expertise

Research related to pain including the use of new pain medications, brain function in people with pain, complementary and alternative therapies, and new methodologies for understanding how patients report their pain in clinical trials. Current research includes ongoing studies of acupuncture for the treatment of pain in osteo-arthritis patients and chronic fatigue in cancer patients, brain imaging of patients with pain, and studies of cancer treatment related pain.

Description of Clinical Expertise

Focuses on all aspects of pain and symptom therapy in cancer patients as a member of the Symptom and Palliative Care Team and as a collaborator in the development of a multi-disciplinary program for the evaluation and treatment of patients with pain.

Selected Publications

Hohenschurz-Schmidt DJ, Cherkin D, Rice ASC, Dworkin RH, Turk DC, McDermott MP, Bair MJ, DeBar LL, Edwards RR, Farrar JT, Kerns RD, Markman JD, Rowbotham MC, Sherman KJ, Wasan AD, Cowan P, Desjardins P, Ferguson M, Freeman R, Gewandter JS, Gilron I, Grol-Prokopczyk H, Hertz SH, Iyengar S, Kamp C, Karp BI, Kleykamp BA, Loeser JD, Mackey S, Malamut R, McNicol E, Patel KV, Sandbrink F, Schmader K, Simon L, Steiner DJ, Veasley C, Vollert J: Research Objectives and General Considerations for Pragmatic Clinical Trials of Pain Treatments: IMMPACT Statement. Pain 164(7): 1457-1472, July 2023.

Stephens-Shields AJ, Lai HH, Landis JR, Kreder K, Rodriguez LV, Naliboff BD, Afari N, Sutcliffe S, Moldwin R, Griffith JW, Clemens JQ, Bradley CS, Quallich S, Gupta P, Harte SE, Farrar JT: Clinically Important Differences for Pain and Urinary Symptoms in Urological Chronic Pelvic Pain Syndrome: A MAPP Network Study. Journal of Urology 209(6): 1132-1140, June 2023.

Aamodt WW, Bilker WB, Willis AW, Farrar JT: Sociodemographic and Geographic Disparities in End-of-Life Health Care Intensity Among Medicare Beneficiaries With Parkinson Disease. Neurology: Clinical Practice 13(4), May 2023.

Colloca L, Dworkin RH, Farrar JT, Tive L, Yang J, Viktrup L, Dasic G, West CR, Whalen E, Brown MT, Gilbert SA, Verburg KM: Predicting Treatment Responses in Patients With Osteoarthritis: Results From Two Phase III Tanezumab Randomized Clinical Trials. Clinical Pharmacology & Therapeutics 113(4): 878-886, April 2023.

Coyne KS, Barsdorf AI, Mazière JY, Pierson RF, Lanza ST, Farrar JT, Gelfand CHJ, Porter LN, Schnoll SH, Butler SF: Identification of prescription opioid misuse and abuse behaviors and risk factors in chronic pain patients using the Prescription Opioid Misuse and Abuse Questionnaire (POMAQ). Current Medical Research and Opinion 39(3): 441–450, March 2023.

Coyne KS, Schnoll SH, Butler SF, Barsdorf AI, Currie BM, Mazière JY, Pierson RF, Porter LN, Franks CMJ Jr, Farrar JT.: Clinical Scoring Algorithm for the Prescription Opioid Misuse and Abuse Questionnaire (POMAQ). Current Medical Research and Opinion May 2022 Notes: doi: 10.1080/03007995.2022.2065139. Epub ahead of print.

Langford DJ, Lou R, Sheen S, Amtmann D, Colloca L, Edwards RR, Farrar JT, Katz NP, McDermott MP, Reeve BB, Wasan AD, Turk DC, Dworkin RH, Gewandter JS.: Expectations for Improvement: A Neglected but Potentially Important Covariate or Moderator for Chronic Pain Clinical Trials. Pain 24(4): 575-581, April 2022.

Aoyagi K, Liew JW, Farrar JT, Wang N, Carlesso L, Kumar D, Frey Law L, Lewis CE, Nevitt M, Neogi T.: Does Weight-Bearing Versus Non-Weight-Bearing Pain Reflect Different Pain Mechanisms in Knee Osteoarthritis?: The Multicenter Osteoarthritis Study (MOST). Osteoarthritis Cartilage 30(4): 545-550, Apr 2022.

Farrar JT, Bilker WB, Cochetti PT, Argoff CE, Haythornthwaite J, Katz NP, Gilron I: Evaluating the Stability of Opioid efficacy over 12 months in patients with chronic noncancer pain who initially demonstrate benefit from extended release oxycodone or hydrocodone: harmonization of Food and Drug Administration patient-level drug safety study data. Pain 163(1): 47-57, Jan 2022.

Giordano NA, Richmond TS, Farrar JT, 'Trip' Buckenmaier Iii CC, Gallagher RM, Polomano RC.: Differential Pain Presentations Observed across Post-Traumatic Stress Disorder Symptom Trajectories after Combat Injury. Pain Medicine 22(11): 2638-2647, Nov 2021.

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Last updated: 08/02/2023
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