Andrew H Matthews, MD, MSCE

faculty photo
Assistant Professor of Clinical Medicine (Hematology-Oncology)
Attending, Hospital of the University of Pennsylvania
Director of Inpatient Oncology Operations, Hospital of the University of Pennsylvania
Hematology Oncology Fellowship Assistant Program Director, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Perelman Center for Advanced Medicine
12 South Pavilion
Philadelphia, PA 19104
Education:
BA (Biology, Molecular Biology, Economics, Business and Public Policy)
University of Pennsylvania , 2009.
MD (Medicine)
Sidney Kimmel Medical College, Thomas Jefferson University, 2016.
MSCE
Perelman School of Medicine at the University of Pennsylvania , 2022.
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Selected Publications

Wang X, Gimotty PA, Matthews AH, Mamtani R, Luger SM, Hexner EO, Babushok DV, McCurdy SR, Frey NV, Bruno XJ, Gill S, Martin ME, Paralkar VR, Maillard I, Porter DL, Loren AW, Perl AE, Pratz KW, Getz KD, Lai C.: Evolving racial/ethnic disparities in AML survival in the novel therapy era. Blood Adv 9: 533-544, Feb 2025.

Rowe M, Babushok D, Carroll M, Carulli A, Frey N, Gill S, Hexner E, Hirsh R, Hossain N, Lai C, Loren A, Luger S, Maillard I, McCurdy S, Matthews A, Martin ME, Paralkar VR, Perl A, Porter D, Pratz K, Stadtmauer E, Bruno XJ.: Tumor Lysis Syndrome in Acute Myeloid Leukemia Patients Treated With a Venetoclax Based Regimen. Eur J Haematol Dec 2024.

Takeshi Onoue, Andrew H Matthews, Azin Vakilpour, Yu Kang, Bénédicte Lefebvre, Amanda M Smith, Shannon R McCurdy, Michael G Fradley, Joseph Carver, Jesse Chittams, Marielle Scherrer-Crosbie: Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines. Cardio-Oncology 10(1), Nov 2024 Notes: DOI: 10.1186/s40959-024-00275-5.

Matthew P Connor, Neeharika Prathapa, Noelle V Frey, Saar I Gill, Elizabeth O Hexner, Ximena Jordan Bruno, Catherine E Lai, Alison W Loren, Selina M Luger, Andrew H Matthews, Shannon R McCurdy, Alexander E Perl, David L Porter, Arlene Zeringue, Joseph H Oved, Timothy S Olson, Keith W Pratz, Daria V Babushok: Hypomethylating agents are associated with high rates of hematologic toxicity in patients with secondary myeloid neoplasms developing after acquired aplastic anemia. Haematologica 8(109): 2732-2737, Aug 2024.

Laczko D, Poveda-Rogers C, Matthews AH, Snaith O, Luger S, Bagg A, Caponetti GC, Morrissette JJD, Yang G.: RAD21 mutations in acute myeloid leukemia. Leuk & Lymphoma Mar 2024.

Matthews A, Fenu E, Skuli SJ, Harris JC, Lai C.: Immunohistochemistry-based detection of TP53 mutations in acute myeloid leukemia: a promising high sensitivity diagnostic approach. Leuk & Lymphoma Mar 2024.

Abaza Y, Winer ES, Murthy GSG, Shallis RM, Matthews AH, Badar T, Geramita EM, Kota VK, Swaroop A, Doukas P, Bradshaw D, Helenowski IB, Liu Y, Zhang H, Im A, Litzow MR, Perl AE, Atallah E, Altman JK.: Clinical outcomes of hypomethylating agents plus Venetoclax as frontline treatment in patients 75 years and older with acute myeloid leukemia: Real‐world data from eight US academic centers. Am J Hematol 99(4), Feb 2024.

Matthews AH, Perl AE, Luger SM, Gill SI, Lai C, Porter DL, Skuli S, Bruno XJ, Carroll MP, Freyer CW, Carulli A, Babushok DV, Frey NV, Hexner EO, Martin ME, McCurdy SR, Stadtmauer EA, Loren AW, Paralkar VR, Maillard IP, Pratz KW.: Real-world effectiveness of intensive chemotherapy with 7&3 versus venetoclax and hypomethylating agent in acute myeloid leukemia. Am J Hematol Jun 2023.

Matthews AH, Perl AE, Luger SM, Loren AW, Gill SI, Porter DL, Babushok DV, Maillard I, Carroll MP, Frey NV, Hexner E, Martin ME, McCurdy SR, Stadtmauer EA, Paralkar VR, Jordan Bruno X, Hwang WT, Margolis D, Pratz KW. : Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia. Blood Adv 6(13): 3997-4005, Jul 2022.

Matthews AH, Yui J, Chiang EY, Pishko AM, Cuker A, Cucchiara BL, George D, Sayani F, Mullen MT.: Cerebral Infarction due to Severe ADAMTS-13 Deficiency with Normal Hematological Parameters: A Potential Cause of Cryptogenic Stroke. J Stroke Cerebrovasc Dis. J Stroke Cerebrovasc Dis 31(6): 106431, Jun 2022.

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Last updated: 04/17/2025
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