Mario Cristancho, M.D.
Associate Professor of Clinical Psychiatry
Clinician, Neuromodulation Service (TMS, Vagus Nerve Stimulation, ECT, and Deep Brain Stimulation), Dept. of Psychiatry, University of Penn., Philadelphia,PA
Attending Physician, Pennsylvania Hospital, Department of Psychiatry, Philadelphia,PA
Attending Physician, Hospital of the University of Pennsylvania, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Clinician, Comprehensive Consultation Service Mood Disorders Treatment Center, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Medical Director, Electroconvulsive Therapy service., Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Medical Director, Transcranial magnetic stimulation and neuromodulation program, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Chief of Interventional Psychiatry, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Department: Psychiatry
Contact information
3535 Market Street
Mezzanine
Philadelphia, PA 19104
Mezzanine
Philadelphia, PA 19104
Office: 215-746-7181
Fax: 215-746-4116
Fax: 215-746-4116
Education:
M.D.
Universidad Industrial de Santander (UIS), Colombia , 2005.
Permanent linkM.D.
Universidad Industrial de Santander (UIS), Colombia , 2005.
Selected Publications
Young-Hoon Nho, Liming Qiu, Robert L. Seilheimer, Gustavo Campos, Andrew Chang, Zhengjia Wang, John F. Magnotti, Michael S. Beauchamp, Daniel A.N. Barbosa, Andreas Horn, Nolan R. Williams, Lily A. Brown, Taneeta M. Ganguly, Mario Cristancho, Bijan Pesaran, Desmond J. Oathes, Kai J. Miller, Katherine W. Scangos, Casey H. Halpern, : Human orbitofrontal neural activity is linked to obsessive-compulsive behavioral dynamics. Cell February 2026 Notes: Accepted for publication.Robert L. Seilheimer, Liming Qiu, Giovanna Rocchio, Young-Hoon Nho, Gustavo Campos, Andreas Horn, Camarin E. Rolle, Vivek P. Buch, T. Mindy Ganguly, Mario Cristancho, Desmond J. Oathes, Lily Brown, Bijan Pesaran, Andrew D. Krystal, Eddie F. Chang, Moses A. Lee, Kai J. Miller, Daniel A.N. Barbosa, Nolan R. Williams, Casey H. Halpern, Katherine W. Scangos: Stereo-encephalography-guided multi-lead deep brain stimulation for treatment-refractory obsessive-compulsive disorder - Study design and individualized surgical targeting approach. Journal of Affective Disorders 2026.
Zachary P Rosenthal, Joseph B. Majeski, Ala Somarowthu, Davin K Quinn, Britta E. Lindquist, Mary E. Putt, Antoneta Karaj, Chris G Favilla, Wesley B. Baker, Golkoo Hosseini, Jenny P Rodriguez, Mario A Cristancho, Yvette I Sheline, C. William Shuttleworth11, Christopher C. Abbott, Arjun G Yodh, Ethan M Goldberg: Electroconvulsive therapy generates a post-ictal wave of spreading depolarization in mice and humans Nature Communications 2025
Choi W, Nho YH, Qiu L, Chang A, Campos G, Seilheimer RL, Wilent WB, Bakalov D, Firdous N, Kerr M, Joshi D, Maze G, Topalovic U, Batista D, Suthana N, Amaro A, Hayes MR, Cajigas I, Cristancho M, Allison KC, Pesaran B, Scangos KW, Gold JI, Wadden TA, Halpern CH. : Brain activity associated with breakthrough food preoccupation in an individual on tirzepatide. Nature Medicine November 2025.
Zheng J, Sheline Y, Cristancho M et al. : Vagus Nerve Stimulation for Treatment-Resistant Depression. Poster presented at The Dwight l. Evans, MD Penn Psychiatry Research Day. Philadelphia, PA April 2025.
Connolly Gibbons, M.B., Tyler, J., Crits-Christoph, P., Cristancho, M., Galbraith, J., Chiu, R., Duong, L.A., Oquendo, M.A., Calloway, Amber: A Multifaceted Outpatient Treatment Model Designed to Optimize Treatment Outcomes and Access to Care Poster presented at The Dwight l. Evans, MD Penn Psychiatry Research Day. Philadelphia, PA April 2025.
Nicholas T. Trapp, Anthony Purgianto, Joseph J. Taylor, Manpreet K. Singh, Lindsay M. Oberman, Brian J. Mickey, Nagy A. Youssef, Daniela Solzbacher, Benjamin Zebley, Laura Y. Cabrera, Susan Conroy, Mario Cristancho, Jackson R. Richards, Michael J. Flood, Tracy Barbour, Daniel M. Blumberger, Stephan F. Taylor, David Feifel, Irving M. Reti, Shawn M. McClintock, Sarah H. Lisanby, Mustafa M. Husain: Consensus Review and Considerations on TMS to Treat Depression. Poster presented at the 6th International Brain Stimulation Conference, Kobe Japan February 2025.
Nicholas T. Trapp, Anthony Purgianto, Joseph J. Taylor, Manpreet K. Singh, Lindsay M. Oberman, Brian J. Mickey, Nagy A. Youssef, Daniela Solzbacher, Benjamin Zebley, Laura Y. Cabrera, Susan Conroy, Mario Cristancho, Jackson R. Richards, Michael J. Flood, Tracy Barbour, Daniel M. Blumberger, Stephan F. Taylor, David Feifel, Irving M. Reti, Shawn M. McClintock, Sarah H. Lisanby, Mustafa M. Husain: Consensus review and considerations on TMS to treat depression: A comprehensive update endorsed by the National Network of Depression Centers, the Clinical TMS Society, and the International Federation of Clinical Neurophysiology. Clinical Neurophysiology 170, February 2025.
Tyler, J., Connolly Gibbons, M. B., Crits-Christoph, P., Cristancho, M., Galbraith, J., Chiu, R. Y., Duong, L. A., & Oquendo, M. A.: A multifaceted outpatient treatment model for mood and anxiety disorders designed to optimize both treatment outcomes and access to care. Annual Convention of the Association for Behavioral and Cognitive Therapies. New Orleans, LA, United States. 2025.
Romain J Duprat 1, Kristin A Linn 2, Theodore D Satterthwaite 3, Yvette I Sheline 4, Ximo Liang 1, Gabriela Bagdon 1, Matthew W Flounders 1, Heather Robinson 1, Michael Platt 5, Joseph Kable 6, Hannah Long 1, Morgan Scully 1, Joseph A Deluisi 1, Michael Thase 7, Mario Cristancho 7, Julie Grier 1, Camille Blaine 1, Almaris Figueroa-González 1, Desmond J Oathes 8: Resting fMRI-guided TMS evokes subgenual anterior cingulate response in depression. Neuroimage December 2024.