Mario Cristancho, M.D.

Associate Professor of Clinical Psychiatry
Clinician, Neuromodulation Service (TMS, Vagus Nerve Stimulation, ECT, and Deep Brain Stimulation), Dept. of Psychiatry, University of Penn., Philadelphia,PA
Attending Physician, Pennsylvania Hospital, Department of Psychiatry, Philadelphia,PA
Attending Physician, Hospital of the University of Pennsylvania, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Clinician, Comprehensive Consultation Service Mood Disorders Treatment Center, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Attending Physician, Department of Family Medicine and Community Health, University of Pennsylvania, Perelman School of Medicine. Philadelphia, PA
Medical Director, Electroconvulsive Therapy service., Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Medical Director, Transcranial magnetic stimulation and neuromodulation program, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Chief of Interventional Psychiatry, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia,PA
Department: Psychiatry
Contact information
3535 Market Street
Mezzanine
Philadelphia, PA 19104
Mezzanine
Philadelphia, PA 19104
Office: 215-746-7181
Fax: 215-746-4116
Fax: 215-746-4116
Education:
M.D.
Universidad Industrial de Santander (UIS), Colombia , 2005.
Permanent linkM.D.
Universidad Industrial de Santander (UIS), Colombia , 2005.
Selected Publications
Zachary P Rosenthal, Joseph B. Majeski, Ala Somarowthu, Davin K Quinn, Britta E. Lindquist, Mary E. Putt, Antoneta Karaj, Chris G Favilla, Wesley B. Baker, Golkoo Hosseini, Jenny P Rodriguez, Mario A Cristancho, Yvette I Sheline, C. William Shuttleworth11, Christopher C. Abbott, Arjun G Yodh, Ethan M Goldberg: Electroconvulsive therapy generates a post-ictal wave of spreading depolarization in mice and humans Nature Communications 2025 Notes: Accepted for publication.Zheng J, Sheline Y, Cristancho M et al. : Vagus Nerve Stimulation for Treatment-Resistant Depression. Poster presented at The Dwight l. Evans, MD Penn Psychiatry Research Day. Philadelphia, PA April 2025.
Connolly Gibbons, M.B., Tyler, J., Crits-Christoph, P., Cristancho, M., Galbraith, J., Chiu, R., Duong, L.A., Oquendo, M.A., Calloway, Amber: A Multifaceted Outpatient Treatment Model Designed to Optimize Treatment Outcomes and Access to Care Poster presented at The Dwight l. Evans, MD Penn Psychiatry Research Day. Philadelphia, PA April 2025.
Nicholas T. Trapp, Anthony Purgianto, Joseph J. Taylor, Manpreet K. Singh, Lindsay M. Oberman, Brian J. Mickey, Nagy A. Youssef, Daniela Solzbacher, Benjamin Zebley, Laura Y. Cabrera, Susan Conroy, Mario Cristancho, Jackson R. Richards, Michael J. Flood, Tracy Barbour, Daniel M. Blumberger, Stephan F. Taylor, David Feifel, Irving M. Reti, Shawn M. McClintock, Sarah H. Lisanby, Mustafa M. Husain: Consensus Review and Considerations on TMS to Treat Depression. Poster presented at the 6th International Brain Stimulation Conference, Kobe Japan February 2025.
Nicholas T. Trapp, Anthony Purgianto, Joseph J. Taylor, Manpreet K. Singh, Lindsay M. Oberman, Brian J. Mickey, Nagy A. Youssef, Daniela Solzbacher, Benjamin Zebley, Laura Y. Cabrera, Susan Conroy, Mario Cristancho, Jackson R. Richards, Michael J. Flood, Tracy Barbour, Daniel M. Blumberger, Stephan F. Taylor, David Feifel, Irving M. Reti, Shawn M. McClintock, Sarah H. Lisanby, Mustafa M. Husain: Consensus review and considerations on TMS to treat depression: A comprehensive update endorsed by the National Network of Depression Centers, the Clinical TMS Society, and the International Federation of Clinical Neurophysiology. Clinical Neurophysiology 170, February 2025.
Romain J Duprat 1, Kristin A Linn 2, Theodore D Satterthwaite 3, Yvette I Sheline 4, Ximo Liang 1, Gabriela Bagdon 1, Matthew W Flounders 1, Heather Robinson 1, Michael Platt 5, Joseph Kable 6, Hannah Long 1, Morgan Scully 1, Joseph A Deluisi 1, Michael Thase 7, Mario Cristancho 7, Julie Grier 1, Camille Blaine 1, Almaris Figueroa-González 1, Desmond J Oathes 8: Resting fMRI-guided TMS evokes subgenual anterior cingulate response in depression. Neuroimage December 2024.
Pecsok MK, Mordy A, Cristancho MA, Oathes D, Roalf DR.: The Glutamatergic Effects of Clinical Repetitive Transcranial Magnetic Stimulation in Depressed Populations: A Preliminary Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies. Psychopathology July 2024.
Cristancho M, Fava M, Ingelfinger J, Nikayin S, Sanacora G. : Depression - Advanced Treatments for Treatment-Resistant Depression. The New England Journal of Medicine. May 2024.
Zandi P, Morreale M, Reti I, Maixner D, McDonald W, Patel P, Achtyes E, Bhati M, Carr B, Conroy S, Cristancho M, Dubin M, Francis A, Glazer K, Ingram W, Khurshid K, McClintock S, Pinjari O, Reeves K, Rodriguez N, Sampson S, Seiner S, Selek S, Sheline Y, Smetana R, Soda T, Trapp N, Wright J, Hussain M, Weiner R: National Network of Depression centers' Recommendations on Harmonizing Clinical Documentation of Electroconvulsive Therapy. The Journal of ECT March 2022.
Hitti,FL.,Cristancho,MA.,Yang,A., O'Reardon JP., Bhati MT., Baltuch,GH: Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment Resistant Depression: A Decade of Clinical Follow-up The Journal of Clinical Psychiatry October 2021.