Kandace L Gollomp, MD
Assistant Professor of Pediatrics (Hematology)
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
Abramson Research Center, Office 316E
3615 Civic Center Blvd
Philadelphia, PA 19147
Abramson Research Center, Office 316E
3615 Civic Center Blvd
Philadelphia, PA 19147
Office: 2154592468
Publications
Education:
BA (English)
Yale University, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2010.
Permanent linkBA (English)
Yale University, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2010.
Description of Clinical Expertise
Pediatric benign hematologyDescription of Research Expertise
My research focuses on therapies that modify neutrophil extracellular traps (NETs) to improve their ability to capture pathogens including viruses and bacteria, while decreasing their ability to induce harm to host tissue. Such treatments may improve outcomes in conditions such as sepsis, sickle cell disease, heparin-induced thrombocytopenia, and anti-phospholipid antibody syndromeSelected Publications
Abby Skidmore, Nate D. Levine, Veronica Bochenek,Manuela Roggiani,Mark Goulian, Kandace Gollomp, Anh T. P. Ngo, PhD1: Platelet factor 4 modulates the bactericidal ability of neutrophil extracellular traps. 65th Annual Meeting of the American Society of Hematology, San Diego, CA December 2023 Notes: Poster, Accepted.Kemar V. Prussien, Andrea H. Roe, Veronica Bochenek, Jessica Wu, Seema Bhatnagar, Sandy Luz, Kandace Gollomp: Socio-economic and Inflammatory Correlates of Plasma Cortisol Among Individuals with Sickle Cell Disease. 65th Annual Meeting of the American Society of Hematology, San Diego, CA December 2023 Notes: Poster, Accepted.
Molly Brakhane, Vittorio Abbonante, Angelo B.A. Laranjeira, Christian Di Buduo, Brooke Sadler, Katrina Ashworth, Tim Kong, Fan He, Mary Fulbright, Dong Chen, Regina Clemens, Elena Pegoraro, Michelle Lambert, Kandace Gollomp, Jorge Di Paola, Alessandra Balduini, Stephen T. Oh: Aberrant Activity of the Calcium Sensor STIM1 Underlies Congenital Platelet Disorders and Myeloproliferative Neoplasms. 65th annual meeting of the American Society of Hematology, San Diego, CA December 2023 Notes: Podium Presentation, Accepted.
Veronica Bochenek, Nate Levine, Anh TP Ngo, Samir Maarouf, Abigail Skidmore, M Anna Kowalska, Caroline Diorio, Zachary Martinez, Mortimer Poncz, Kandace Gollomp: Peptidyl arginine deiminase (PAD) 4 modulates the GI microbiome and baseline inflammation in mice: Implications for sepsis. 65th Annual Meeting of the American Society of Hematology, San Diego, CA December 2023 Notes: Poster, Accepted.
Anh T. P. Ngo, Nate D. Levine,Abby Skidmore,Amrita Sarkar, Veronica Bochenek, Manuela Roggiani, Mark Goulian, Mortimer Poncz, Kandace Gollomp: Platelet factor 4 enhances antimicrobial function of the endothelium and improves outcome in a murine model of sepsis. 65th Annual Meeting of the American Society of Hematology, San Diego, CA December 2023 Notes: Poster, Accepted.
Anh Tp Ngo, Abigail Skidmore, Jenna Oberg, Irene Yarovoi, Amrita Sarkar, Nate Levine, Veronica Bochenek, Guohua Zhao, Lubica Rauova, M Anna Kowalska, Kaitlyn Eckart, Nilam S Mangalmurti, Ann Rux, Douglas B Cines, Mortimer Poncz, Kandace Gollomp: Platelet factor 4 limits neutrophil extracellular trap- and cell-free DNA-induced thrombogenicity and endothelial injury. JCI Insight 8(22), Nov 2023 Notes: DOI: 10.1172/jci.insight.171054.
Matthew R Schuelke, Hamid Bassiri, Edward M Behrens, Scott Canna, Colleen Croy, Amanda DiNofia, Kandace Gollomp, Stephan Grupp, Michele Lambert, Arathi Lambrix, Shannon L Maude, Regina Myers, Haley Newman, Whitney Petrosa, Alix Seif, Kathleen E Sullivan, David T Teachey, Caroline Diorio: Emapalumab for the treatment of refractory cytokine release syndrome in pediatric patients. Blood Advances 7(18): 5603-5607, September 2023.
Anh Ngo, Veronica Bocehenek, Kandace Gollomp: The Immunology of platelet factor 4-Polyanion interactions. Current Opinions in Hematology 30(6): 219-229, Aug 2023.
Anh T. Ngo, Veronica Bochenek, Nate Levine, Amrita Sarkar, Lubica Rauova, M. Anna Kowalska, Mortimer Poncz, Kandace Gollomp: Platelet factor 4 (PF4) enhances bacterial uptake and clearance by the endothelium, contributing to improved outcomes in sepsis. ISTH 2023 Congress, Montreal, Canada June 2023 Notes: Podium Presentation.
Lubica Rauova, Jenna Oberg, Conroy O. Field, Nate Levine, Kandace Gollomp, Gowthami M. Arepally, Douglas B. B. Cines, Taylor Cohen, Mortimer Poncz: Chadox1 Exposure-Induced Neutrophil-Activating Peptide 2 (NAP2) Antibodies: Murine-Based Insights into The Pathogenesis of Thrombosis with Thrombocytopenia Syndrome (TTS). ISTH 2023 Congress, Montreal, Canada June 24-28 2023 Notes: Podium Presentation.