Selected Publications

Dowd S, Sharo C, Abdulmalik O, Elmer J.: Optimizing the lyophilization of Lumbricus terrestris erythrocruorin. Artif Cells Nanomed Biotechnol 52(1): 291-299, Dec 2024.

Osheiza Abdulmalik, Kandace Gollomp, Veronica Bochenek, Conroy O Field, Mariana Macias, Benita Balogun, Salma Roland, Martin K Safo, Yan Zhang, Akua Donkor, Abdelsattar Omar, Moustafa El-Araby, David R. Light, Clark Brown, Andrew N Fleischman: A Novel Direct Hemoglobin S Polymerization Inhibitor for the Treatment of Sickle Cell Disease – In Vivo Efficacy of Ilx-002 in Humanized Mice. Blood. 66th ASH Annual Meeting and Exposition. San Diego, CA. Podium 144((Supplement 1)): 173, November 2024.

Elizabeth A. Traxler, Chad Komar, Megan Saari, Quynn Hotan, A Josephine Thrasher, Eugene Khandros, Kunhua Qin, Osheiza Abdulmalik, Claire Shao, Qingzhou Chen, Andy J. Minn, Cheryl A. Keller, Junwei Shi, Gerd A. Blobel: A Novel Genome-Scale CRISPR-Cas12a Screen Identifies Ptpa As a Fetal Hemoglobin Regulator Via BCL11A. Blood.66th ASH Annual Meeting and Exposition. San Diego, CA. Podium. 144 ((Supplement 1)): 412, November 2024.

Riley JS, Berkowitz CL, Luks VL, Dave A, Cyril-Olutayo MC, Pogoriler J, Flake AW, Abdulmalik O, Peranteau WH.: Immune modulation permits tolerance and engraftment in a murine model of late-gestation transplantation. Blood Adv 8: 4523-4538, Sep 2024.

Chappell ME, Breda L, Tricoli L, Guerra A, Jarocha DJ, Castruccio Castracani C, Papp TE, Tanaka N, Hamilton N, Triebwasser MP, Ghiaccio V, Fedorky M, Gollomp K, Bochenek V, Roche AM, Everett JK, Cook EJ, Bushman FD, Teawtrakul N, Glentis S, Kattamis A Prof, Mui BL, Tam YK, Weissman D, Abdulmalik O, Parhiz H, Rivella S.: Use of HSC Targeted LNP to Generate a Mouse Model of Lethal α-Thalassemia and Treatment via Lentiviral Gene Therapy. Blood 144: 1633-1645, Jul 2024.

Pagare PP, McGinn M, Ghatge MS, Shekhar V, Alhashimi RT, Daniel Pierce B, Abdulmalik O, Zhang Y, Safo MK.: The antisickling agent, 5-hydroxymethyl-2-furfural: Other potential pharmacological applications. Med Res Rev 44(6): 2707-2729, Jun 2024.

Osheiza Abdulmalik, Andrew N Fleischman, David R Light, Benita Balogun, Mojisola Cyril-Olutayo, Moustafa El-Araby, Abdelsattar Omar, Martin K Saf0: ILX-002 – A Direct HbS Polymerization Inhibitor for the Treatment of Sickle Cell Disease. Journal of Sickle Cell Disease. 18th Annual Sickle Cell Disease Research and Educational Symposium and 47th National Sickle Cell Disease Scientific Meeting. Fort Lauderdale, FL. Poster Presentation 1(Issue Supplement_1), June 2024.

Pavani G, Klein JG, Nations CC, Sussman JH, Tan K, An HH, Abdulmalik O, Thom CS, Gearhart PA, Willett CM, Maguire JA, Chou ST, French DL, Gadue P.: Modeling primitive and definitive erythropoiesis with induced pluripotent stem cells. Blood Adv 8: 1449-1463, Mar 2024.

Marissa Locke Rottinghaus: A road to survival: Cutting-edge genetic therapies offer greater promise for a sickle cell cure. ASBMB Today: The Member Magazine Of The American society for biochemistry and molecular biology https://www.asbmb.org/asbmb-today/science/011724/a-road-to-survival January 2024 Notes: Article on genetic therapies for sickle cell disease where work from our group was featured.

Marissa Locke Rottinghaus: The perfect storm. ASBMB Today: The Member Magazine Of The American society for biochemistry and molecular biology https://www.asbmb.org/asbmb-today/science/120623/the-perfect-storm December 2023 Notes: Article on the impact of some of the work our group has done, and relevance to work done by 2023 Nobel laureates Katalin Karikó and Drew Weissman, who were also featured.