Tejvir S. Khurana, MD, PhD.
Tejvir S. Khurana, MD, PhD.
Professor of Physiology
Department: Physiology
Graduate Group Affiliations
Contact information
Department of Physiology,
University of Pennsylvania,
A600 Richards Building,
3700 Hamilton Walk,
Philadelphia, PA 19004
University of Pennsylvania,
A600 Richards Building,
3700 Hamilton Walk,
Philadelphia, PA 19004
Office: (215) 898-4116
Fax: (215) 573 5851
Fax: (215) 573 5851
Email:
tsk@mail.med.upenn.edu
tsk@mail.med.upenn.edu
Education:
MBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
Permanent linkMBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
Description of Research Expertise
muscle, muscular disease, muscular dystrophy, therapeutics, gene therapy, extraocular muscle, transcriptome, proteome, genomics, sports medicine, athletic doping, hypoxia, altitude, respiratory, neuromuscular junctions, synapses.Description of Clinical Expertise
High altitude medicineSelected Publications
Pan TC, Zhang RZ, Arita M, Bogdanovich S, Adams SM, Gara SK, Wagener R, Khurana TS, Birk DE,Chu ML: A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16. J Biol Chem Page: 10293-10307, 2014.Mosqueira M, Baby SM, Lahiri S, Khurana TS.: Ventilatory Chemosensory Drive Is Blunted in the mdx Mouse Model of Duchenne Muscular Dystrophy (DMD). PLoS One 8(7):e69567, 2013.
Arsenault PR, Pei F, Lee R, Kerestes H, Percy MJ, Keith B, Simon MC, Lappin TR, Khurana TS, Lee FS: A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism. J Biol Chem 288: 33571-33584, 2013.
Gerhart-Hines Z, Feng D, Emmett MJ, Everett LJ, Loro E, Briggs ER, Bugge A, Hou C, Ferrara C, Seale P, Pryma DA, Khurana TS, Lazar MA: The nuclear receptor Rev-erbα controls circadian thermogenic plasticity. Nature 503: 410-413, 2013.
Krajacic P, Pistilli EE, Tanis JE, Khurana TS, Lamitina ST: FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice. Biol Open 2: 1245-1252, 2013.
Tan Q, Kerestes H, Percy MJ, Pietrofesa R, Chen L, Khurana TS, Christofidou-Solomidou M, Lappin TR, Lee FS: Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation. J Biol Chem 288: 17134-17144, 2013.
Pan TC, Zhang RZ, Markova D, Arita M, Zhang Y, Bogdanovich S, Khurana TS, Bönnemann CG, Birk DE, Chu ML: COL6A3 protein deficiency in mice leads to muscle and tendon defects similar to human collagen VI congenital muscular dystrophy. J Biol Chem 288: 14320-14331, 2013.
Mosqueira M, Willmann G, Zeiger U, Khurana TS: Expression profiling reveals novel hypoxic biomarkers in peripheral blood of adult mice exposed to chronic hypoxia. PLoS One 7(5): e37497, 2012.
Moorwood C, Soni N, Patel G, Wilton SD, Khurana TS: A Cell-Based High-Throughput Screening Assay for Posttranscriptional Utrophin Upregulation. J Biomol Screen 2012.
Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T*: Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy. Am. J.Path. 178: 1287-1297, 2011.