Paul J Planet, Ph.D, M.D.

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Assistant Professor of Pediatrics
Chair of Institutional Biosafety Comittee, Children's Hospital of Philadelphia
Co-Director Microbial Archive and Cryocollection, Children's Hospital of Philadelphia
Department: Pediatrics
Graduate Group Affiliations

Contact information
Children's Hospital of Philadelphia
3615 Civic Center Blvd
Abramson 1202A
Philadelphia, PA 19104
Office: 9175140695
BS (Molecular Biophysics & Biochemistry and Anthropology)
Yale University, New Haven, CT, 1996.
Ph.D (Integrated Program for Cellular, Molecular, and Biophysical Studies)
Columbia University College of Physicians & Surgeons, New York, NY , 2003.
Columbia University College of Physicians & Surgeons, New York, NY, 2004.
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Description of Clinical Expertise

Dr. Planet is a pediatric infectious disease specialist. Dr. Planet has specific areas of interest in antibiotic resistant infections (MRSA), respiratory infections, and chronic infections in patients with cystic fibrosis.

Description of Other Expertise

Evolution of SARS-CoV-2

Description of Research Expertise

Paul J. Planet MD, PhD is an Assistant Professor of Pediatrics at the Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania. He is also a senior researcher at the American Museum of Natural History.

Dr. Planet graduated from Yale University with a Bachelors degree in Anthropology and Molecular Biochemistry & Biophysics. He went on to earn his MD and PhD from Columbia University, where he also completed his residency and fellowship training at the Children’s Hospital of New York. His first faculty appointment was in the division of Pediatric Infectious Disease at Columbia University.

Dr. Planet’s research program focuses on the evolution and ecology of infectious disease. His current interests include the evolution and spread of antibiotic resistant strains, particularly community acquired MRSA, and the impact of the pulmonary microbiome in cystic fibrosis. Dr. Planet’s laboratory uses whole genome phylogenetics, high-throughput sequencing, and bioinformatics to generate hypotheses that are then tested with bench-based microbiology and molecular techniques.

Selected Publications

92. Lal A, Moustafa AM, Planet PJ* : Efficient Pangenome Construction through Alignment-Free Residue Pangenome Analysis. bioRxiv July 2022.

Tsukahara K, Johnson B, Klimowich K, Chiotos K, Jensen EA, Planet PJ, Phinizy P, Piccione J: Comparison of tracheal aspirate and bronchoalveolar lavage samples in the microbiological diagnosis of lower respiratory tract infection in pediatric patients. Pediatr Pulmonol July 2022.

Narechania A, Bobo D, Deitz K, Desalle R, Planet PJ, Mathema B : Hill numbers at the edge of a pandemic: rapid SARS-COV2 surveillance without alignments or trees medRxiv June 2022.

Marques AD, Sherrill-Mix S, Everett JK, Reddy S, Hokama P, Roche AM, Hwang Y, Glascock A, Whiteside SA, Graham-Wooten J, Khatib LA, Fitzgerald AS, Moustafa AM, Bianco C, Rajagopal S, Helton J, Deming R, Denu L, Ahmed A, Kitt E, Coffin SE, Newbern C, Mell JC, Planet PJ, Badjatia N, Richards B, Wang ZX, Cannuscio CC, Strelau KM, Jaskowiak-Barr A, Cressman L, Loughrey S, Ganguly A, Feldman MD, Collman RG, Rodino KG, Kelly BJ, Bushman FD: SARS-CoV-2 Variants Associated with Vaccine Breakthrough in the Delaware Valley through Summer 2021. MBio February 2022.

Lubin JB, Green J, Maddux S, Denu L, Duranova T, Lanza M, Wynosky-Dolfi M, Brodsky IE, Planet PJ*, Silverman MA : Arresting microbiome development limits immune system maturation and resistance to infection bioRxiv January 2022.

Handel AS, Muller WJ, Planet PJ : Metagenomic Next-Generation Sequencing (mNGS): SARS-CoV-2 as an Example of the Technology's Potential Pediatric Infectious Disease Applications. J Pediatric Infect Dis Soc December 2021.

Saenkham-Huntsinger P, Hyre AN, Hanson BS, Donati GL, Adams LG, Ryan C, Londoño A, Moustafa AM, Planet PJ, Subashchandrabose S: Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection. mBio 7, September 2021.

Martini CL, Coronado AZ, Melo MCN, Gobbi CN, Lopez ÚS, de Mattos MC, Amorim TT, Botelho AMN, Vasconcelos ATR, Almeida LGP, Planet PJ, Zingali RB, Figueiredo AMS, Ferreira-Carvalho BT: Cellular Growth Arrest and Efflux Pumps Are Associated with Antibiotic Persisters in Streptococcus pyogenes Induced in Biofilm-Like Environments. Front Microbiol. Front Microbiol September 2021.

Zichello J, Gupta P, Scott M, Desai B, Cohen R, Halderman L, Perkins S, Porzecanski A, Planet PJ, Wyner Y, Blaser M, Burk R, Diamond J, Kennett R, Borland J, DeSalle R. : A natural history museum visitor survey of perception, attitude and knowledge (PAK) of microbes and antibiotics. PLoS September 2021.

Moustafa AM, Planet PJ.: Jumping a Moving Train: SARS-CoV-2 Evolution in Real Time. J Pediatric Infect Dis Soc. August 2021.

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Last updated: 11/07/2022
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