Paul J Planet, Ph.D, M.D.

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
The Children's Hospital of Philadelphia
3615 Civic Center Blvd
Abramson 1202A
Philadelphia, PA 19104
Office: 9175140695
Education:
BS (Molecular Biophysics & Biochemistry and Anthropology)
Yale University, New Haven, CT, 1996.
Ph.D (Integrated Program for Cellular, Molecular, and Biophysical Studies)
Columbia University College of Physicians & Surgeons, New York, NY , 2003.
MD
Columbia University College of Physicians & Surgeons, New York, NY, 2004.
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Description of Clinical Expertise

Dr. Planet is a pediatric infectious disease specialist. Dr. Planet has specific areas of interest in antibiotic resistant infections (MRSA), respiratory infections, and chronic infections in patients with cystic fibrosis.

Description of Research Expertise

Paul J. Planet MD, PhD is an Assistant Professor of Pediatrics at the Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania. He is also a senior researcher at the American Museum of Natural History.

Dr. Planet graduated from Yale University with a Bachelors degree in Anthropology and Molecular Biochemistry & Biophysics. He went on to earn his MD and PhD from Columbia University, where he also completed his residency and fellowship training at the Children’s Hospital of New York. His first faculty appointment was in the division of Pediatric Infectious Disease at Columbia University.

Dr. Planet’s research program focuses on the evolution and ecology of infectious disease. His current interests include the evolution and spread of antibiotic resistant strains, particularly community acquired MRSA, and the impact of the pulmonary microbiome in cystic fibrosis. Dr. Planet’s laboratory uses whole genome phylogenetics, high-throughput sequencing, and bioinformatics to generate hypotheses that are then tested with bench-based microbiology and molecular techniques.

Selected Publications

Peignier A, Planet PJ, Parker D : Differential induction of type I and III interferons by Staphylococcus aureus. Infect Immun July 2020.

Moustafa AM, Lal A and Planet PJ: Comparative genomics in infectious disease. Curr Opin Microbiol April 2020.

Cuthbertson L, Walker AW, Oliver AE, Rogers GB, Rivett DW, Hampton TH, Ashare A, Elborn JS, De Soyza A, Carroll MP, Hoffman LR, Lanyon C, Moskowitz SM, O’toole GA, Parkhill J, Planet PJ, Teneback CC, Tunney MM, Zuckerman JB, Bruce KD, Van Der Gast CJ : Lung Function And Microbiota Diversity In Cystic Fibrosis. Microbiome April 2020.

70. Rios R, Reyes J, Carvajal LP, Rincon S, Panesso D, Echeverri AM, Dinh A, Kolokotronis SO, Narechania A, Tran TT, Munita JM, Murray BE, Planet PJ, Arias CA, Diaz L : Genomic Epidemiology of Vancomycin-Resistant Enterococcus faecium (VREfm) in Latin America: Revisiting The Global VRE Population Structure. Sci Rep March 2020.

Moustafa AM, Planet PJ: WhatsGNU: a tool for identifying proteomic novelty. Genome Biology March 2020.

Bouso, Jennifer M; Yendur, Ozge; Hysinger, Erik; Planet, Paul J; Haas, Andrew; Goldfarb, Samuel; Piccione, Joseph.: Endobronchial Ultrasound-guided Biopsy Is Feasible, Safe, and Improves Diagnostic Yields in Immunocompromised Children. Am J Respir Crit Care Med February 2020.

Khan A, Davlieva M, Panesso D, Rincon S, Miller WR, Diaz L, Reyes J, Cruz MR, Pemberton O, Nguyen AH, Siegel SD, Planet PJ, Narechania A, Latorre M, Rios R, Singh KV, Ton-That H, Garsin DA, Tran TT, Shamoo Y, Arias CA : Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis. Proc Natl Acad Sci U S A December 2019.

Bouso, Jennifer M; Planet, Paul J.: Complete nontuberculous mycobacteria whole genomes using an optimized DNA extraction protocol for long-read sequencing. BMC Genomics 30(20), October 2019.

Hlavaty SI, Chang YM, Orth RP, Goulian M, Planet PJ, Thamm DH, Punt JA, Garden OA: Bacterial Killing Activity of Polymorphonuclear Myeloid-Derived Suppressor Cells Isolated From Tumor-Bearing Dogs. Frontiers Immunology October 2019.

Acker KP, Wong Fok Lung T, West E, Craft J, Narechania A, Smith H, O'Brien K, Moustafa AM, Lauren C, Planet PJ, Prince A: Strains of Staphylococcus aureus that Colonize and Infect Skin Harbor Mutations in Metabolic Gene. iScience September 2019.

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Last updated: 08/23/2020
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