Adam Cuker, MD, MS

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Associate Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Assistant Director, Hospital of the University of Pennsylvania Specialized Coagulation Laboratory
Associate Director of Clinical Research, Penn-CHOP Blood Center for Patient Care and Discovery
Clinical Director, Penn Blood Disorders Center , University of Pennsylvania, University of Pennsylvania
Director, Penn Comprehensive Hemophilia and Thrombosis Program
Section Chief of Benign Hematology, Division of Hematology/Oncology, Perelman School of Medicine
Co-director, PGY2 Thrombosis and Hemostasis Pharmacy Residency Program, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Penn Comprehensive Hemophilia and Thrombosis Program
HUP, 3 Dulles
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-8012
Fax: 215-615-6599
BS (Biological Sciences)
Cornell University, 1998.
MD (Medicine)
Yale University, 2003.
MS (Translational Research)
University of Pennsylvania, 2010.
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Description of Clinical Expertise

Clotting disorders, Bleeding disorders, Platelet disorders

Description of Research Expertise

Heparin-induced thrombocytopenia, Immune thrombocytopenia, Thrombosis, Anticoagulation, Platelet disorders, Bleeding disorders

Selected Publications

Cuker A, Rux AH, Hinds JL, Dela Cruz M, Yarovoi SV, Brown IAM, Yang W, Konkle BA, Arepally GM, Watson SP, Cines DB, Sachais BS: Novel diagnostic assays for heparin-induced thrombocytopenia. Blood 121(18): 3727-3732, 2013.

Cuker A, Cines DB: Protamine-induced thrombocytopenia? Blood 121: 2818-2819, 2013

Siegal D, Cuker A: Reversal of novel oral anticoagulants in patients with major bleeding. J Thromb Thrombolysis 35(3): 391-398, 2013

Sood S, Cuker A, Wang C, Metjian A, Chiang E, Soucie J, Konkle B: Similarity in Joint Function Limitation in Type 3 Von Willebrand Disease and Moderate Haemophilia A. Haemophilia 19(4): 595-601, 2013

Tanhehco YC, Cuker A, Rudnick M, Sachais BS: Investigation of a potential protective mechanism against heparin-induced thrombocytopenia in patients on chronic intermittent hemodialysis. Thromb Res 131(3): 244-248, 2013

Cuker A, Gimotty PA, Crowther MA, Warkentin TE: Predictive value of the 4Ts scoring system for heparin-induced thromboctopenia: a systematic review and meta-analysis. Blood 120(20): 4160-4167, 2012

Sachais BS, Litvinov RI, Yarovoi SV, Rauova L, Hinds JL, Rux AH, Arepally GM, Poncz M, Cuker A, Weisel JW, Cines DB: Dynamic antibody binding properties in the pathogenesis of HIT. Blood 120(5): 1137-1142, 2012.

Martinez M, Cuker A, Mills A, Lightfoot R, Fan Y, Tang W, Hazen SL, Ischiropoulos H: Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism. Free Radic Biol Med 53(2): 230-236, 2012.

Cuker A, Cines DB: How I treat heparin-induced thrombocytopenia. Blood 119(10): 2209-2218, 2012

Lakshmanan S, Cuker A: Comtemporary management of primary immune thrombocytopenia (ITP) in adults. J Thromb Haemost 10(10): 1988-1998, 2012

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Last updated: 05/24/2024
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