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Gregory J. Nadolski, M.D.

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Associate Professor of Radiology at the Hospital of the University of Pennsylvania
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Co-Director, Penn Image Guided Interventions (PIGI) Laboratory
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Active Radiologist, Pennsylvania Hospital
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Active Radiologist, Penn Presbyterian Medical Center
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Attending Radiologist, Hospital of the University of Pennsylvania
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Active Medical Staff, Chester County Hospital 7
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IR Research Oversight Committee Member, University of Pennsylvania
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Member IR/DR Residency Selection Committee, University of Pennsylvania
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IR Representative Center for Surgical Health, University of Pennsylvania
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Department: Radiology
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46 Contact information
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Hospital of the University of Pennsylvania
1f Department of Radiology
15 1 Silverstein
35 3400 Spruce Street
Philadelphia, PA 19104
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2e Office: 215.662.7892
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13 Education:
21 9 B.S. 19 (Biochemistry) c
3e University of Wisconsin, Madison, WI , 2001.
21 9 M.D. 15 (Medicine) c
52 Indiana University School of Medicine, Indianapolis, IN , 2007.
21 7 MS 23 (Translational Research) c
45 University of Pennsylvania, Philadelphia, PA, 2017.
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Description of Clinical Expertise

a8 My research and clinical interests include multimodality therapies for the treatment of hepatocellular carcinoma and liver dominant metastatic cancer.
12c I have initiated or participated in multiple clinical trials at the Hospital of the University of Pennsylvania for treating hepatocellular carcinoma and metastatic cancers to the liver. Several of these trials are multi-modality treatments in collaboration with other medical subspecialties.
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152 My other area of clinical and research interest is lymphatic injury, dysfunction, and malformations. Clinically, I perform thoracic duct embolization to treat chylothorax. I participate in research investigating novel lymphatic interventions to treat chylothorax, chylous ascites, refractory ascites and protein losing enteropathy.
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Description of Research Expertise

10b My clinical and research expertise center on lymphatic interventions and multimodality cancer therapies to treat primary and secondary liver tumors. I also conduct research on diseases of the liver such as treatment of portal hypertension and ascites.
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Selected Publications

dd M Sheng, T Gade, G Nadolski: Management of Hepatic Metastases from Colorectal Cancer. Digestive Disease Interventions (Book). Springer Nature, 2026.

156 Elisabeth R Seyferth 1, Gregory J Nadolski 1, Jeffrey I Mondschein 1, Ryan M Cobb 1, Scott O Trerotola 1: Factors affecting the difficulty of transurethral double J stent removal in patients with renal transplants. Diagnostic and Interventional Radiology November 2025.

27c M Angela Aznar 1, Charly R Good 2, Julie S Barber-Rotenberg 3, Sangya Agarwal 3, Wesley Wilson 3, Alex Watts 4, Zhen Zhang 2, Donna Gonzales 3, Greg Donahue 2, Wei-Ting Hwang 4, Austin K Rennels 3, Andrew J Rech 3, Shunichiro Kuramitsu 3, Hua Huang 5, Karl M Glastad 2, Katherine A Alexander 2, Gabriela Plesa 3, Emily Dowd 3, Andrea Brennan 3, Donald L Siegel 1, Janos Tanyi 6, Andrew Haas 7, Drew A Torigian 8, Gregory Nadolski 8, Vanessa E Gonzalez 3, Elizabeth O Hexner 9, Joseph A Fraietta 10, Julie K Jadlowsky 3, Regina M Young 11, Shelley L Berger 12, Carl H June 13, Mark H O'Hara 14 9d : Clinical and molecular dissection of CAR T cell resistance in pancreatic cancer. Cell Reports Medicine 6(9), September 2025.

175 Alexey Gurevich 1, Gregory J Nadolski 1, Ansar Z Vance 1, Ryan-Assaad El-Ghazal 2, Raphael Cohen 3, Timothy W I Clark 1, Matthew L Hung 4: Tunneled dialysis catheter placement in intensive care unit patients: influence of catheter tip design on clinical performance. CVIR Endovascular September 2025.

196 Hung ML, Jairam A, Carr M, Berman ZT, Taddonio M, Minocha J, Aryafar H, Mondschein JI, Soulen MC, Nadolski GJ, Redmond J. : Transjugular intrahepatic portosystemic shunt creation using intravascular ultrasound vs fluoroscopic guidance: A dual-institution retrospective comparative study. World Journal of Hepatology 17(5), May 2025.

10f Moon HE, Hur S, Moon J, Lee SH, Choi H, Ratnam L, Nadolski G, Itkin M.: Lymphatic Embolization for Primary Genital Lymphorrhea and Chylous Reflux-Related Lower Limb Lymphedema. JVIR 36(5), May 2025.

123 Cornman-Homonoff J, Fortune BE, Kolli KP, Kothary N, Nadolski G, Thornburg BG, Verma S, Madoff DC: Management of Ascites: AJR Expert Panel Narrative Review. AJR Am J Roentgenology April 2025 Notes: epub ahead of print.

171 Gurevich A, Islam A, Wakim J, Yarsky E, Kiefer R, El-Ghazal R, McClung G, Cormode DP, Nadolski GJ, Avritscher R, Hunt SJ, Gade TPF: Comparison of Liquid with Particle Embolics in a Translational Rat Model of Hepatocellular Carcinoma: Histologic and Radiographic Responses. JVIR 36(4), April 2025.

16a K. Rao,S. Kayfan,R. Romano,...G. Nadolski, R. Cobb,S. Hunt,M. Soulen: Premedication with NK-1 Antagonists and COX-2 Inhibitors Improves Same-Day Discharge Rates Following Chemoembolization for Hepatocellular Carcinoma and Neuroendocrine Liver Metastasis. JVIR 36(3S): S109-110, March 2025.

12e J. Kus,G. Nadolski,S. Hunt,...S. Shamimi-Noori,M. Soulen,D. DePietro: Utility of Alpha-Fetoprotein (AFP) Monitoring After Y-90 Radioembolization of Hepatocellular Carcinoma in Non-AFP Producers. JVIR 36(3S): S199-200, March 2025.

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