David A Pegues, MD

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Ground Founders Building, Hospital of the University of Pennsylvania, 3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-614-1614
Fax: 215-662-7971
BA (Biology)
University of Chicago, 1982.
University of Chicago Pritzker School of Medicine, 1986.
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Description of Clinical Expertise

Transplant infectious diseases, healthcare-associated infections including catheter-associated urinary tract infections, Salmonellosis

Description of Research Expertise

Dr. Pegues’ current research interests include include developing clinical decision support tools to improve testing stewardship and to reduce inappropriate device utilization; evaluating novel technologies and implementation strategies to reduce environmental microbial contamination and infection risk; and the prevention and control of device-associated infections in high-risk patient populations, including dialysis, oncology, and solid organ transplant.

Selected Publications

Escobar DJ, Pegues DA: How nurses can educate the “thoughtless person playing with penicillin” Jt Comm J Qual Patient Saf 46: 605-7, Nov 2020.

Fang FC, Benson CA, del Rio C, Edwards KM, Fowler VG, Fredricks DN, Limaye AP, Murray BE, Nagie S, Pappas PG, Patel R, Paterson DL, Pegues DA, Petri WA, Schooley RT: COVID-19—Lessons Learned and questions remaining. Clin Infect Dis 20 Oct 26;ciaa1654. doi: 10.1093/cid/ciaa1654. Online ahead of print. Oct 2020.

Read TD, Jacko NF, Petit RA, Pegues DA, David MZ: Genomic clustering of methicillin-resistant Staphylococcus aureus (MRSA) causing bloodstream infection in hospitalized adults, 2018-2019. IDWeek 2020 Oct 2020.

Anesi GL, Meyer NJ, Reilly JP, Schweickert WD, Mikkelsen ME, Myers EV, Dickinson ET, Kelly MP, Pegues DA, Fishman NO. : Preparedness tested: Severe cerebral malaria presenting as a high-risk person under investigation for Ebola virus disease at a U.S. hospital. . Disaster Med Public Health Prep 8: 1-6, May 2020.

Ziegler M, Pegues D, Landsburg D, Gaynes S, Desphy-Carter A, Omorogbe J, Gilmar C, Tolomeo P, Gorman T, Palmer M, Harker C, Lautenbach E, Han J: Enhanced environmental cleaning to reduce rates of Clostridioides difficile infection on oncology units. 6th Decennial International Conference on Healthcare Associated Infections, Atlanta, GA Mar 2020.

Zeigler M, Landsburg D, Pegues D, Bilker W, Gilmar C, Kucharczuk C, Gorman T, Bink K, Moore, A, Stadtmauer E, Fitzpatrick R, Mangan P, Kraus K, Han J: Fluoroquinolone prophylaxis is highly effective for the prevention of central line-associated bloodstream infections in autologous stem cell transplant patients. Biol Blood Marrow Transplant 25: 1004-10, Dec 2019.

Burns J, Mersinger K, Saw S, Morgan S, Athans V, Dutcher L, Pegues D, Degnan K, Binkley S, Hamilton K: Characterization of antibiotic superutilizers in the inpatient setting. IDWeek 2019, Washington, DC Oct 2019.

Dutcher L, Degnan K, Lautenbach E, Pegues D, David M, Cluzet V, Cressman L, Bilker W, Tolomeo P, Hamilton KW: Improving outpatient antimicrobial prescribing for respiratory tract infections IDWeek 2019, Washington, DC Oct 2019.

Ziegler M, Han JH, Landsburg D, Pegues D, Reesey E, Gilmar C, Gorman T, Bink K, Moore A, Kelly BJ: Impact of levofloxacin for the prophylaxis of bloodstream infection on the gut microbiome in patients with hematologic malignancy Open Forum Infect Dis 6: ofz252, May 2019.

Zeigler M, Freyer C, Landsburg D, Pegues D, Hirsch R, Kucharczuk C, Gilmar C, Gorman T, Palmer M, Harker C, Lightheart E, Han J: Reducing C. difficile risk: guiding appropriate acid suppression in Hematology-Oncology. SHEA Spring 2019 Conference, Boston, MA Apr 2019.

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Last updated: 11/16/2020
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