1e
19
1
49
2
2
18
1b
1d
18
37
52
1d
2 29
1d
25
Matthew J. O'Connor, M.D.
88
52
Professor of Clinical Pediatrics (Cardiology)
28
6f
3
61
Attending Physician, Children's Hospital of Philadelphia
b7
Section Chief, Heart Function, Heart Transplant, and Mechanical Circulatory Support Program, Children's Hospital of Philadelphia
11
Department: Pediatrics
4
1
b
1d
46
Contact information
51
4
3
3
3
2
4
b
1f
51
Children's Hospital of Philadelphia
1e Division of Cardiology
39 3401 Civic Center Blvd
Philadelphia, PA 19104
26
1e Division of Cardiology
39 3401 Civic Center Blvd
Philadelphia, PA 19104
2e
Office: 267-426-2882
30
8f
30
Email:
oconnorm@email.chop.edu
12
oconnorm@email.chop.edu
13
Education:
21 9 B.S. 16 (Chemistry) c
35 College of William and Mary , 2000.
21 9 M.D. c
2f University of Virginia, 2004.
21 9 M.L. c
44 University of Pennsylvania Carey Law School, 2023.
c
3
3
3
3
8d
Permanent link21 9 B.S. 16 (Chemistry) c
35 College of William and Mary , 2000.
21 9 M.D. c
2f University of Virginia, 2004.
21 9 M.L. c
44 University of Pennsylvania Carey Law School, 2023.
c
2 29
21
1e
1d
24
2b
29
27
23
10e Edelson JB, O'Connor MJ, Zhang X, Tomlinson AZ, Rossano JW.: Expedited organ placement is rare in pediatric heart transplantation: a UNOS registry analysis. Circ Heart Fail Page: e013435, Jan 2026.
25d Moon J, Greiten L, VanderPluym C, Peng DM, Butto A, Butts R, Auerbach SR, Su J, Zinn M, Khan S, Byrnes J, Lorts A, Amdani S, Absi M, Dykes J, Joong A, Bearl D, Law S, Nandi D, Wilkens S, Engelhardt K, May L, Vaughn G, Parent JJ, Friedland-Little J, Mokshagundam D, Conway J, Spinner J, Aljohani O, Bleiweis M, Shezad MF, O'Connor MJ: Contemporary outcomes of mechanical circulatory support using paracorporeal continuous flow pump in children: A report from the ACTION learning network. J Heart Lung Transplant 45: 89-100, Jan 2026.
150 Lynch A, Shezad MF, Kroslowitz B, Jeewa A, Dykes J, Law S, O'Connor M, Butts R, Joong A, Lorts A, Amdani S, VanderPluym C.: Multicenter registry analysis of bivalirudin for primary anticoagulation in pediatric Heartmate3 recipients: ACTION analysis. ASAIO J 2026.
14f Kauffman H, Convery MJ, Matsubara D, Miller KE, O'Connor MJ, Quartermain MD, Banerjee A.: Fully automated evaluation of left ventricular global longitudinal strain in normal hearts: an assessment of accuracy in the pediatric population. Pediatr Cardiol Nov 2025.
16e Edelson JB, Schneider L, O'Malley S, Somogie J, Huang J, Li ZN, Boyle C, O'Connor MJ, Paridon S, Lin KY, Rossano JW, Lane-Fall M, Cousino MK: Design and rationale of the MIGHTEE study: motivational interviewing and group heart transplant exercise and education. JHLT Open 11: 100421, Nov 2025.
132 Liversedge M, Wang J, Boustany M, Sharova A, Lin KY, O'Connor MJ, Danziger-Isakov L, Ryan TD, Downes KJ, Otto WR.: Epidemiology of invasive fungal disease in pediatric heart transplant recipients. J Pediatric Infect Dis Soc Nov 2025.
192 Catalano MA, Shin M, Toubat O, Rastogi R, Beqaj H, Iyengar A, Smood BF, Toomey N, Edelson JB, Rossano JW, O'Connor MJ, Ahmed H, Gaynor JW, Maeda K, Mavroudis CD: Listing for pediatric donation after circulatory death heart transplantation is associated with improved waitlist outcomes. J Am Heart Assoc 14: e041633, October 2025.
1dc Edelson JB, Amdani S, Rosenthal DN, Kroslowitz B, Morray B, Law S, Joong A, Wilkens S, Peng DM, Ploutz M, Murray J, Lantz J, Esch JJ, Iqbal M, Lancaster T, VanderPluym C, Jeewa A, Shugh S, Absi M, Shezad M, O'Connor MJ, Lorts A, Tume S: Multi-institutional outcomes of Impella use in pediatric patients: A brief communication from the ACTION Network. J Heart Lung Transplant 44: 1668-1671, October 2025.
1be O'Connor MJ, Vu C, Zhang X, Bennett L, Ahmed H, Edwards JJ, Lin KY, Li Y, Maeda K, Marcellus B, Monos D, Rossano JW, Wittlieb-Weber CA, Edelson JB.: Allosensitization status predicts excess mortality in pediatric congenital heart disease transplant recipients in the current era: an analysis of the United Network for Organ Sharing database. JHLT Open 10: 100406, Oct 2025.
2c
7
1d
1f
Selected Publications
1d8 Montgomery CM, Rastogi R, Dewitt A, Kozyak BW, Ha L, Weiss F, Eichner JR, Ahmed H, Tang J, Maeda K, Chaudhary AA, Lane-Fall M, Rosenthal T, Gardner MM, Li ZN, Rossano J, O'Connor MJ, Wittlieb-Weber C, Edelson JB: Implementing a programmatic approach to identify and promote ventricular recovery in pediatric patients supported with ventricular assist devices. J Am Heart Assoc 15: e045453, Feb 2026.10e Edelson JB, O'Connor MJ, Zhang X, Tomlinson AZ, Rossano JW.: Expedited organ placement is rare in pediatric heart transplantation: a UNOS registry analysis. Circ Heart Fail Page: e013435, Jan 2026.
25d Moon J, Greiten L, VanderPluym C, Peng DM, Butto A, Butts R, Auerbach SR, Su J, Zinn M, Khan S, Byrnes J, Lorts A, Amdani S, Absi M, Dykes J, Joong A, Bearl D, Law S, Nandi D, Wilkens S, Engelhardt K, May L, Vaughn G, Parent JJ, Friedland-Little J, Mokshagundam D, Conway J, Spinner J, Aljohani O, Bleiweis M, Shezad MF, O'Connor MJ: Contemporary outcomes of mechanical circulatory support using paracorporeal continuous flow pump in children: A report from the ACTION learning network. J Heart Lung Transplant 45: 89-100, Jan 2026.
150 Lynch A, Shezad MF, Kroslowitz B, Jeewa A, Dykes J, Law S, O'Connor M, Butts R, Joong A, Lorts A, Amdani S, VanderPluym C.: Multicenter registry analysis of bivalirudin for primary anticoagulation in pediatric Heartmate3 recipients: ACTION analysis. ASAIO J 2026.
14f Kauffman H, Convery MJ, Matsubara D, Miller KE, O'Connor MJ, Quartermain MD, Banerjee A.: Fully automated evaluation of left ventricular global longitudinal strain in normal hearts: an assessment of accuracy in the pediatric population. Pediatr Cardiol Nov 2025.
16e Edelson JB, Schneider L, O'Malley S, Somogie J, Huang J, Li ZN, Boyle C, O'Connor MJ, Paridon S, Lin KY, Rossano JW, Lane-Fall M, Cousino MK: Design and rationale of the MIGHTEE study: motivational interviewing and group heart transplant exercise and education. JHLT Open 11: 100421, Nov 2025.
132 Liversedge M, Wang J, Boustany M, Sharova A, Lin KY, O'Connor MJ, Danziger-Isakov L, Ryan TD, Downes KJ, Otto WR.: Epidemiology of invasive fungal disease in pediatric heart transplant recipients. J Pediatric Infect Dis Soc Nov 2025.
192 Catalano MA, Shin M, Toubat O, Rastogi R, Beqaj H, Iyengar A, Smood BF, Toomey N, Edelson JB, Rossano JW, O'Connor MJ, Ahmed H, Gaynor JW, Maeda K, Mavroudis CD: Listing for pediatric donation after circulatory death heart transplantation is associated with improved waitlist outcomes. J Am Heart Assoc 14: e041633, October 2025.
1dc Edelson JB, Amdani S, Rosenthal DN, Kroslowitz B, Morray B, Law S, Joong A, Wilkens S, Peng DM, Ploutz M, Murray J, Lantz J, Esch JJ, Iqbal M, Lancaster T, VanderPluym C, Jeewa A, Shugh S, Absi M, Shezad M, O'Connor MJ, Lorts A, Tume S: Multi-institutional outcomes of Impella use in pediatric patients: A brief communication from the ACTION Network. J Heart Lung Transplant 44: 1668-1671, October 2025.
1be O'Connor MJ, Vu C, Zhang X, Bennett L, Ahmed H, Edwards JJ, Lin KY, Li Y, Maeda K, Marcellus B, Monos D, Rossano JW, Wittlieb-Weber CA, Edelson JB.: Allosensitization status predicts excess mortality in pediatric congenital heart disease transplant recipients in the current era: an analysis of the United Network for Organ Sharing database. JHLT Open 10: 100406, Oct 2025.
2c